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Author: Manolis Kellis

Rankings

  • All-time downloads: 83,925 (rank: 1,581 (tie) )
  • Categories:
    • bioinformatics: 10,922 (rank: 658 (tie) )
    • cancer biology: 4,922 (rank: 606 (tie) )
    • cell biology: 1,796 (rank: 3,458 (tie) )
    • developmental biology: 1,094 (rank: 3,370 (tie) )
    • epidemiology: 618 (rank: 12,865 (tie) )
    • evolutionary biology: 501 (rank: 13,328 (tie) )
    • genetic and genomic medicine: 397 (rank: 4,711 (tie) )
    • genetics: 9,988 (rank: 1,689 )
    • genomics: 40,620 (rank: 189 )
    • infectious diseases: 3,870 (rank: 8,867 (tie) )
    • molecular biology: 2,677 (rank: 1,471 )
    • neuroscience: 497 (rank: 43,070 (tie) )
    • psychiatry and clinical psychology: 2,582 (rank: 205 (tie) )
    • synthetic biology: 1,634 (rank: 904 (tie) )
    • systems biology: 1,807 (rank: 2,263 (tie) )

Downloads per author, site-wide

Preprints

Discovery and characterization of coding and non-coding driver mutations in more than 2,500 whole cancer genomes

genomics more details view paper
  • Downloaded 5,458 times
  • Download rankings, all-time:
    • Site-wide: 1,760
    • In genomics: 168
  • Year to date:
    • Site-wide: 20,076
  • Since beginning of last month:
    • Site-wide: 21,377

Local genetic effects on gene expression across 44 human tissues

genomics more details view paper
  • Downloaded 4,452 times
  • Download rankings, all-time:
    • Site-wide: 2,333
    • In genomics: 257
  • Year to date:
    • Site-wide: 55,410
  • Since beginning of last month:
    • Site-wide: 48,145

High-resolution genome-wide functional dissection of transcriptional regulatory regions in human

genomics more details view paper
  • Downloaded 3,911 times
  • Download rankings, all-time:
    • Site-wide: 2,810
    • In genomics: 319
  • Year to date:
    • Site-wide: 68,739
  • Since beginning of last month:
    • Site-wide: 57,577

Mathematical analysis of Cordoba calcifediol trial suggests strong role for Vitamin D in reducing ICU admissions of hospitalized COVID-19 patients

infectious diseases more details view paper
  • Downloaded 3,870 times
  • Download rankings, all-time:
    • Site-wide: 2,857
    • In infectious diseases: 569
  • Year to date:
    • Site-wide: 427
  • Since beginning of last month:
    • Site-wide: 488

Thousands of novel unannotated proteins expand the MHC I immunopeptidome in cancer

cancer biology more details view paper
  • Downloaded 3,754 times
  • Download rankings, all-time:
    • Site-wide: 2,990
    • In cancer biology: 43
  • Year to date:
    • Site-wide: 2,009
  • Since beginning of last month:
    • Site-wide: 1,764

Phylogenetic Identification and Functional Characterization of Orthologs and Paralogs across Human, Mouse, Fly, and Worm

genomics more details view paper
  • Downloaded 3,536 times
  • Download rankings, all-time:
    • Site-wide: 3,255
    • In genomics: 367
  • Year to date:
    • Site-wide: 13,543
  • Since beginning of last month:
    • Site-wide: 14,607

Integrative analysis of 10,000 epigenomic maps across 800 samples for regulatory genomics and disease dissection

genomics more details view paper
  • Downloaded 3,369 times
  • Download rankings, all-time:
    • Site-wide: 3,493
    • In genomics: 392
  • Year to date:
    • Site-wide: 2,284
  • Since beginning of last month:
    • Site-wide: 4,528

A Bayesian approach to mediation analysis predicts 206 causal target genes in Alzheimer's disease

genetics more details view paper
  • Downloaded 3,361 times
  • Download rankings, all-time:
    • Site-wide: 3,511
    • In genetics: 137
  • Year to date:
    • Site-wide: 18,110
  • Since beginning of last month:
    • Site-wide: 16,164

Distant regulatory effects of genetic variation in multiple human tissues

genomics more details view paper
  • Downloaded 2,768 times
  • Download rankings, all-time:
    • Site-wide: 4,609
    • In genomics: 514
  • Year to date:
    • Site-wide: 64,297
  • Since beginning of last month:
    • Site-wide: 61,970

Single-cell dissection of schizophrenia reveals neurodevelopmental-synaptic axis and transcriptional resilience

psychiatry and clinical psychology more details view paper
  • Downloaded 2,582 times
  • Download rankings, all-time:
    • Site-wide: 5,091
    • In psychiatry and clinical psychology: 15
  • Year to date:
    • Site-wide: 1,719
  • Since beginning of last month:
    • Site-wide: 1,816

Simultaneous profiling of DNA methylation and chromatin architecture in mixed populations and in single cells

genomics more details view paper
  • Downloaded 2,438 times
  • Download rankings, all-time:
    • Site-wide: 5,574
    • In genomics: 639
  • Year to date:
    • Site-wide: 40,734
  • Since beginning of last month:
    • Site-wide: 37,693

SARS-CoV-2 gene content and COVID-19 mutation impact by comparing 44 Sarbecovirus genomes

genomics more details view paper
  • Downloaded 2,357 times
  • Download rankings, all-time:
    • Site-wide: 5,840
    • In genomics: 662
  • Year to date:
    • Site-wide: 4,692
  • Since beginning of last month:
    • Site-wide: 5,760

DECODE-ing sparsity patterns in single-cell RNA-seq

bioinformatics more details view paper
  • Downloaded 2,245 times
  • Download rankings, all-time:
    • Site-wide: 6,279
    • In bioinformatics: 730
  • Year to date:
    • Site-wide: 80,558
  • Since beginning of last month:
    • Site-wide: 86,036

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

genomics more details view paper
  • Downloaded 2,092 times
  • Download rankings, all-time:
    • Site-wide: 6,949
    • In genomics: 769
  • Year to date:
    • Site-wide: 126,309
  • Since beginning of last month:
    • Site-wide: 110,068

A probabilistic framework to dissect functional cell-type-specific regulatory elements and risk loci underlying the genetics of complex traits

bioinformatics more details view paper
  • Downloaded 2,037 times
  • Download rankings, all-time:
    • Site-wide: 7,217
    • In bioinformatics: 858
  • Year to date:
    • Site-wide: 94,488
  • Since beginning of last month:
    • Site-wide: 128,933

mRNA structure dynamics identifies the embryonic RNA regulome

molecular biology more details view paper
  • Downloaded 1,927 times
  • Download rankings, all-time:
    • Site-wide: 7,860
    • In molecular biology: 196
  • Year to date:
    • Site-wide: 69,968
  • Since beginning of last month:
    • Site-wide: 56,768

Best practices for genome-wide RNA structure analysis: combination of mutational profiles and drop-off information

bioinformatics more details view paper
  • Downloaded 1,877 times
  • Download rankings, all-time:
    • Site-wide: 8,193
    • In bioinformatics: 993
  • Year to date:
    • Site-wide: 27,715
  • Since beginning of last month:
    • Site-wide: 19,162

A multiresolution framework to characterize single-cell state landscapes

genomics more details view paper
  • Downloaded 1,872 times
  • Download rankings, all-time:
    • Site-wide: 8,217
    • In genomics: 899
  • Year to date:
    • Site-wide: 34,181
  • Since beginning of last month:
    • Site-wide: 44,873

Modeling prediction error improves power of transcriptome-wide association studies

genetics more details view paper
  • Downloaded 1,856 times
  • Download rankings, all-time:
    • Site-wide: 8,323
    • In genetics: 391
  • Year to date:
    • Site-wide: 52,390
  • Since beginning of last month:
    • Site-wide: 61,725

Single-cell interactomes of the human brain reveal cell-type specific convergence of brain disorders

systems biology more details view paper
  • Downloaded 1,807 times
  • Download rankings, all-time:
    • Site-wide: 8,674
    • In systems biology: 157
  • Year to date:
    • Site-wide: 47,054
  • Since beginning of last month:
    • Site-wide: 37,735

Multi-tissue polygenic models for transcriptome-wide association studies

genetics more details view paper
  • Downloaded 1,800 times
  • Download rankings, all-time:
    • Site-wide: 8,712
    • In genetics: 410
  • Year to date:
    • Site-wide: 86,187
  • Since beginning of last month:
    • Site-wide: 91,045

Convergence of dispersed regulatory mutations predicts driver genes in prostate cancer

genomics more details view paper
  • Downloaded 1,798 times
  • Download rankings, all-time:
    • Site-wide: 8,719
    • In genomics: 951
  • Year to date:
    • Site-wide: 24,683
  • Since beginning of last month:
    • Site-wide: 26,216

Conserved epigenetic regulatory logic infers genes governing cell identity

cell biology more details view paper
  • Downloaded 1,796 times
  • Download rankings, all-time:
    • Site-wide: 8,738
    • In cell biology: 214
  • Year to date:
    • Site-wide: 34,221
  • Since beginning of last month:
    • Site-wide: 48,412

Nearly all new protein-coding predictions in the CHESS database are not protein-coding

genomics more details view paper
  • Downloaded 1,750 times
  • Download rankings, all-time:
    • Site-wide: 9,104
    • In genomics: 998
  • Year to date:
    • Site-wide: 25,059
  • Since beginning of last month:
    • Site-wide: 42,915

High-Throughput 5′ UTR Engineering for Enhanced Protein Production in Non-Viral Gene Therapies

synthetic biology more details view paper
  • Downloaded 1,634 times
  • Download rankings, all-time:
    • Site-wide: 10,072
    • In synthetic biology: 107
  • Year to date:
    • Site-wide: 9,836
  • Since beginning of last month:
    • Site-wide: 6,739

Genome-wide regulatory model from MPRA data predicts functional regions, eQTLs, and GWAS hits

bioinformatics more details view paper
  • Downloaded 1,633 times
  • Download rankings, all-time:
    • Site-wide: 10,076
    • In bioinformatics: 1,221
  • Year to date:
    • Site-wide: 57,083
  • Since beginning of last month:
    • Site-wide: 42,452

Single-cell deconvolution of 3,000 post-mortem brain samples for eQTL and GWAS dissection in mental disorders

genomics more details view paper
  • Downloaded 1,563 times
  • Download rankings, all-time:
    • Site-wide: 10,735
    • In genomics: 1,169
  • Year to date:
    • Site-wide: 606
  • Since beginning of last month:
    • Site-wide: 1,773

Functional enrichments of disease variants across thousands of independent loci in eight diseases

genetics more details view paper
  • Downloaded 1,260 times
  • Download rankings, all-time:
    • Site-wide: 14,848
    • In genetics: 735
  • Year to date:
    • Site-wide: 99,391
  • Since beginning of last month:
    • Site-wide: 91,415

A gene expression atlas of embryonic neurogenesis in Drosophila reveals complex spatiotemporal regulation of lncRNAs.

developmental biology more details view paper
  • Downloaded 1,094 times
  • Download rankings, all-time:
    • Site-wide: 18,311
    • In developmental biology: 314
  • Year to date:
    • Site-wide: 27,844
  • Since beginning of last month:
    • Site-wide: 26,093

Predicting trait regulators by identifying co-localization of DNA binding and GWAS variants in regulatory regions

bioinformatics more details view paper
  • Downloaded 935 times
  • Download rankings, all-time:
    • Site-wide: 23,006
    • In bioinformatics: 2,718
  • Year to date:
    • Site-wide: 71,858
  • Since beginning of last month:
    • Site-wide: 74,820

Evidence of a recombination rate valley in human regulatory domains

genomics more details view paper
  • Downloaded 921 times
  • Download rankings, all-time:
    • Site-wide: 23,528
    • In genomics: 2,276
  • Year to date:
    • Site-wide: 84,860
  • Since beginning of last month:
    • Site-wide: 109,747

A causal inference framework for estimating genetic variance and pleiotropy from GWAS summary data

bioinformatics more details view paper
  • Downloaded 919 times
  • Download rankings, all-time:
    • Site-wide: 23,622
    • In bioinformatics: 2,794
  • Year to date:
    • Site-wide: 41,731
  • Since beginning of last month:
    • Site-wide: 57,224

Genus-wide characterization of bumblebee genomes reveals variation associated with key ecological and behavioral traits of pollinators

genomics more details view paper
  • Downloaded 800 times
  • Download rankings, all-time:
    • Site-wide: 28,702
    • In genomics: 2,641
  • Year to date:
    • Site-wide: 27,081
  • Since beginning of last month:
    • Site-wide: 28,703

Structural variant selection for high-altitude adaptation using single-molecule long-read sequencing

genomics more details view paper
  • Downloaded 795 times
  • Download rankings, all-time:
    • Site-wide: 28,944
    • In genomics: 2,652
  • Year to date:
    • Site-wide: 1,455
  • Since beginning of last month:
    • Site-wide: 401

Evolutionary dynamics of abundant stop codon readthrough in Anopheles and Drosophila

molecular biology more details view paper
  • Downloaded 750 times
  • Download rankings, all-time:
    • Site-wide: 31,426
    • In molecular biology: 886
  • Year to date:
    • Site-wide: 75,157
  • Since beginning of last month:
    • Site-wide: 49,451

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

genomics more details view paper
  • Downloaded 740 times
  • Download rankings, all-time:
    • Site-wide: 32,014
    • In genomics: 2,845
  • Year to date:
    • Site-wide: 113,953
  • Since beginning of last month:
    • Site-wide: 129,579

RiVIERA-beta: Joint Bayesian inference of risk variants and tissue-specific epigenomic enrichments across multiple complex human diseases

bioinformatics more details view paper
  • Downloaded 706 times
  • Download rankings, all-time:
    • Site-wide: 34,107
    • In bioinformatics: 3,813
  • Year to date:
    • Site-wide: 123,307
  • Since beginning of last month:
    • Site-wide: 105,255

Plasma-derived exosomal analysis and deconvolution enables prediction and tracking of melanoma checkpoint blockade response

cancer biology more details view paper
  • Downloaded 633 times
  • Download rankings, all-time:
    • Site-wide: 39,500
    • In cancer biology: 1,068
  • Year to date:
    • Site-wide: 32,649
  • Since beginning of last month:
    • Site-wide: 26,603

Integrative construction of regulatory region networks in 127 human reference epigenomes by matrix factorization

epidemiology more details view paper
  • Downloaded 618 times
  • Download rankings, all-time:
    • Site-wide: 40,592
    • In epidemiology: 1,935
  • Year to date:
    • Site-wide: 127,661
  • Since beginning of last month:
    • Site-wide: 124,775

Analysis of Genetically Regulated Gene Expression identifies a trauma type specific PTSD gene, SNRNP35

genetics more details view paper
  • Downloaded 615 times
  • Download rankings, all-time:
    • Site-wide: 40,847
    • In genetics: 1,944
  • Year to date:
    • Site-wide: 112,976
  • Since beginning of last month:
    • Site-wide: 81,748

Evidence for secondary-variant genetic burden and non-random distribution across biological modules in a recessive ciliopathy

genetics more details view paper
  • Downloaded 592 times
  • Download rankings, all-time:
    • Site-wide: 42,918
    • In genetics: 2,020
  • Year to date:
    • Site-wide: 67,156
  • Since beginning of last month:
    • Site-wide: 52,061

Correlating predicted epigenetic marks with expression data to find interactions between SNPs and genes

bioinformatics more details view paper
  • Downloaded 570 times
  • Download rankings, all-time:
    • Site-wide: 45,004
    • In bioinformatics: 4,762
  • Year to date:
    • Site-wide: 79,351
  • Since beginning of last month:
    • Site-wide: 79,543

Pan-cancer screen for mutations in non-coding elements with conservation and cancer specificity reveals correlations with expression and survival

cancer biology more details view paper
  • Downloaded 535 times
  • Download rankings, all-time:
    • Site-wide: 48,559
    • In cancer biology: 1,361
  • Year to date:
    • Site-wide: 133,131
  • Since beginning of last month:
    • Site-wide: 128,439

Various localized epigenetic marks predict expression across 54 samples and reveal underlying chromatin state enrichments

genetics more details view paper
  • Downloaded 504 times
  • Download rankings, all-time:
    • Site-wide: 52,130
    • In genetics: 2,433
  • Year to date:
    • Site-wide: 131,181
  • Since beginning of last month:
    • Site-wide: 126,431

Elucidation of Codon Usage Signatures across the Domains of Life

evolutionary biology more details view paper
  • Downloaded 501 times
  • Download rankings, all-time:
    • Site-wide: 52,435
    • In evolutionary biology: 2,855
  • Year to date:
    • Site-wide: 88,627
  • Since beginning of last month:
    • Site-wide: 85,269

Exome-wide age-of-onset analysis reveals exonic variants in ERN1, TACR3 and SPPL2C associated with Alzheimer's disease

neuroscience more details view paper
  • Downloaded 497 times
  • Download rankings, all-time:
    • Site-wide: 52,907
    • In neuroscience: 7,826
  • Year to date:
    • Site-wide: 59,552
  • Since beginning of last month:
    • Site-wide: 59,206

Counterfactual inference for single-cell gene expression analysis

genetic and genomic medicine more details view paper
  • Downloaded 397 times
  • Download rankings, all-time:
    • Site-wide: 66,930
    • In genetic and genomic medicine: 218
  • Year to date:
    • Site-wide: 3,859
  • Since beginning of last month:
    • Site-wide: 10,385

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