Author: Manolis Kellis
- ORCiD: http://orcid.org/0000-0001-7113-9630
- Most recently observed institution: Broad Institute of MIT and Harvard
Rankings
- All-time downloads: 75,466 (rank: 1,718 )
- Categories:
- bioinformatics: 10,663 (rank: 616 )
- cancer biology: 4,280 (rank: 679 )
- cell biology: 1,732 (rank: 3,172 (tie) )
- developmental biology: 1,011 (rank: 3,226 (tie) )
- epidemiology: 609 (rank: 11,116 (tie) )
- evolutionary biology: 479 (rank: 12,950 (tie) )
- genetics: 9,767 (rank: 1,664 )
- genomics: 36,703 (rank: 214 )
- infectious diseases: 1,984 (rank: 11,828 (tie) )
- molecular biology: 2,623 (rank: 1,322 )
- neuroscience: 461 (rank: 42,034 (tie) )
- psychiatry and clinical psychology: 1,960 (rank: 205 (tie) )
- synthetic biology: 1,436 (rank: 971 (tie) )
- systems biology: 1,758 (rank: 2,136 (tie) )
Downloads per author, site-wide
Preprints
Discovery and characterization of coding and non-coding driver mutations in more than 2,500 whole cancer genomes
genomics more details view paper- Downloaded 5,361 times
- Download rankings, all-time:
- Site-wide: 1,580
- In genomics: 161
- Year to date:
- Site-wide: 11,884
- Since beginning of last month:
- Site-wide: 10,265
Local genetic effects on gene expression across 44 human tissues
genomics more details view paper- Downloaded 4,411 times
- Download rankings, all-time:
- Site-wide: 2,069
- In genomics: 240
- Year to date:
- Site-wide: 85,324
- Since beginning of last month:
- Site-wide: 31,531
High-resolution genome-wide functional dissection of transcriptional regulatory regions in human
genomics more details view paper- Downloaded 3,882 times
- Download rankings, all-time:
- Site-wide: 2,485
- In genomics: 300
- Year to date:
- Site-wide: 66,843
- Since beginning of last month:
- Site-wide: 70,400
Phylogenetic Identification and Functional Characterization of Orthologs and Paralogs across Human, Mouse, Fly, and Worm
genomics more details view paper- Downloaded 3,401 times
- Download rankings, all-time:
- Site-wide: 3,028
- In genomics: 365
- Year to date:
- Site-wide: 8,745
- Since beginning of last month:
- Site-wide: 11,170
A Bayesian approach to mediation analysis predicts 206 causal target genes in Alzheimer's disease
genetics more details view paper- Downloaded 3,258 times
- Download rankings, all-time:
- Site-wide: 3,232
- In genetics: 138
- Year to date:
- Site-wide: 9,365
- Since beginning of last month:
- Site-wide: 11,405
Thousands of novel unannotated proteins expand the MHC I immunopeptidome in cancer
cancer biology more details view paper- Downloaded 3,187 times
- Download rankings, all-time:
- Site-wide: 3,336
- In cancer biology: 52
- Year to date:
- Site-wide: 2,621
- Since beginning of last month:
- Site-wide: 2,606
Integrative analysis of 10,000 epigenomic maps across 800 samples for regulatory genomics and disease dissection
genomics more details view paper- Downloaded 2,846 times
- Download rankings, all-time:
- Site-wide: 3,891
- In genomics: 463
- Year to date:
- Site-wide: 3,432
- Since beginning of last month:
- Site-wide: 4,114
Distant regulatory effects of genetic variation in multiple human tissues
genomics more details view paper- Downloaded 2,736 times
- Download rankings, all-time:
- Site-wide: 4,107
- In genomics: 489
- Year to date:
- Site-wide: 67,612
- Since beginning of last month:
- Site-wide: 38,118
Simultaneous profiling of DNA methylation and chromatin architecture in mixed populations and in single cells
genomics more details view paper- Downloaded 2,390 times
- Download rankings, all-time:
- Site-wide: 5,047
- In genomics: 614
- Year to date:
- Site-wide: 24,303
- Since beginning of last month:
- Site-wide: 40,424
DECODE-ing sparsity patterns in single-cell RNA-seq
bioinformatics more details view paper- Downloaded 2,223 times
- Download rankings, all-time:
- Site-wide: 5,622
- In bioinformatics: 680
- Year to date:
- Site-wide: 59,990
- Since beginning of last month:
- Site-wide: 70,380
Deep-coverage whole genome sequences and blood lipids among 16,324 individuals
genomics more details view paper- Downloaded 2,083 times
- Download rankings, all-time:
- Site-wide: 6,159
- In genomics: 724
- Year to date:
- Site-wide: 99,017
- Since beginning of last month:
- Site-wide: 117,644
SARS-CoV-2 gene content and COVID-19 mutation impact by comparing 44 Sarbecovirus genomes
genomics more details view paper- Downloaded 2,048 times
- Download rankings, all-time:
- Site-wide: 6,318
- In genomics: 742
- Year to date:
- Site-wide: 5,670
- Since beginning of last month:
- Site-wide: 4,981
A probabilistic framework to dissect functional cell-type-specific regulatory elements and risk loci underlying the genetics of complex traits
bioinformatics more details view paper- Downloaded 2,022 times
- Download rankings, all-time:
- Site-wide: 6,442
- In bioinformatics: 793
- Year to date:
- Site-wide: 48,473
- Since beginning of last month:
- Site-wide: 49,769
Mathematical analysis of Cordoba calcifediol trial suggests strong role for Vitamin D in reducing ICU admissions of hospitalized COVID-19 patients
infectious diseases more details view paper- Downloaded 1,984 times
- Download rankings, all-time:
- Site-wide: 6,605
- In infectious diseases: 872
- Year to date:
- Site-wide: 672
- Since beginning of last month:
- Site-wide: 300
Single-cell dissection of schizophrenia reveals neurodevelopmental-synaptic axis and transcriptional resilience
psychiatry and clinical psychology more details view paper- Downloaded 1,960 times
- Download rankings, all-time:
- Site-wide: 6,741
- In psychiatry and clinical psychology: 18
- Year to date:
- Site-wide: 1,930
- Since beginning of last month:
- Site-wide: 537
mRNA structure dynamics identifies the embryonic RNA regulome
molecular biology more details view paper- Downloaded 1,902 times
- Download rankings, all-time:
- Site-wide: 7,050
- In molecular biology: 170
- Year to date:
- Site-wide: 45,020
- Since beginning of last month:
- Site-wide: 56,112
Modeling prediction error improves power of transcriptome-wide association studies
genetics more details view paper- Downloaded 1,822 times
- Download rankings, all-time:
- Site-wide: 7,488
- In genetics: 372
- Year to date:
- Site-wide: 25,719
- Since beginning of last month:
- Site-wide: 33,551
A multiresolution framework to characterize single-cell state landscapes
genomics more details view paper- Downloaded 1,815 times
- Download rankings, all-time:
- Site-wide: 7,533
- In genomics: 857
- Year to date:
- Site-wide: 18,568
- Since beginning of last month:
- Site-wide: 30,165
Best practices for genome-wide RNA structure analysis: combination of mutational profiles and drop-off information
bioinformatics more details view paper- Downloaded 1,801 times
- Download rankings, all-time:
- Site-wide: 7,616
- In bioinformatics: 967
- Year to date:
- Site-wide: 21,872
- Since beginning of last month:
- Site-wide: 13,189
Multi-tissue polygenic models for transcriptome-wide association studies
genetics more details view paper- Downloaded 1,778 times
- Download rankings, all-time:
- Site-wide: 7,770
- In genetics: 385
- Year to date:
- Site-wide: 91,609
- Since beginning of last month:
- Site-wide: 68,262
Single-cell interactomes of the human brain reveal cell-type specific convergence of brain disorders
systems biology more details view paper- Downloaded 1,758 times
- Download rankings, all-time:
- Site-wide: 7,902
- In systems biology: 146
- Year to date:
- Site-wide: 74,915
- Since beginning of last month:
- Site-wide: 26,195
Conserved epigenetic regulatory logic infers genes governing cell identity
cell biology more details view paper- Downloaded 1,732 times
- Download rankings, all-time:
- Site-wide: 8,099
- In cell biology: 199
- Year to date:
- Site-wide: 36,761
- Since beginning of last month:
- Site-wide: 16,175
Convergence of dispersed regulatory mutations predicts driver genes in prostate cancer
genomics more details view paper- Downloaded 1,718 times
- Download rankings, all-time:
- Site-wide: 8,198
- In genomics: 946
- Year to date:
- Site-wide: 13,938
- Since beginning of last month:
- Site-wide: 57,526
Nearly all new protein-coding predictions in the CHESS database are not protein-coding
genomics more details view paper- Downloaded 1,659 times
- Download rankings, all-time:
- Site-wide: 8,680
- In genomics: 1,007
- Year to date:
- Site-wide: 40,315
- Since beginning of last month:
- Site-wide: 29,141
Genome-wide regulatory model from MPRA data predicts functional regions, eQTLs, and GWAS hits
bioinformatics more details view paper- Downloaded 1,598 times
- Download rankings, all-time:
- Site-wide: 9,182
- In bioinformatics: 1,153
- Year to date:
- Site-wide: 48,715
- Since beginning of last month:
- Site-wide: 93,265
High-Throughput 5′ UTR Engineering for Enhanced Protein Production in Non-Viral Gene Therapies
synthetic biology more details view paper- Downloaded 1,436 times
- Download rankings, all-time:
- Site-wide: 10,736
- In synthetic biology: 116
- Year to date:
- Site-wide: 29,962
- Since beginning of last month:
- Site-wide: 7,422
Functional enrichments of disease variants across thousands of independent loci in eight diseases
genetics more details view paper- Downloaded 1,246 times
- Download rankings, all-time:
- Site-wide: 13,335
- In genetics: 689
- Year to date:
- Site-wide: 55,228
- Since beginning of last month:
- Site-wide: 96,288
A gene expression atlas of embryonic neurogenesis in Drosophila reveals complex spatiotemporal regulation of lncRNAs.
developmental biology more details view paper- Downloaded 1,011 times
- Download rankings, all-time:
- Site-wide: 18,267
- In developmental biology: 321
- Year to date:
- Site-wide: 47,777
- Since beginning of last month:
- Site-wide: 35,165
Predicting trait regulators by identifying co-localization of DNA binding and GWAS variants in regulatory regions
bioinformatics more details view paper- Downloaded 908 times
- Download rankings, all-time:
- Site-wide: 21,312
- In bioinformatics: 2,602
- Year to date:
- Site-wide: 69,529
- Since beginning of last month:
- Site-wide: 76,233
Evidence of a recombination rate valley in human regulatory domains
genomics more details view paper- Downloaded 898 times
- Download rankings, all-time:
- Site-wide: 21,665
- In genomics: 2,183
- Year to date:
- Site-wide: 92,879
- Since beginning of last month:
- Site-wide: 78,214
A causal inference framework for estimating genetic variance and pleiotropy from GWAS summary data
bioinformatics more details view paper- Downloaded 871 times
- Download rankings, all-time:
- Site-wide: 22,661
- In bioinformatics: 2,760
- Year to date:
- Site-wide: 28,845
- Since beginning of last month:
- Site-wide: 61,415
Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries
genomics more details view paper- Downloaded 731 times
- Download rankings, all-time:
- Site-wide: 28,970
- In genomics: 2,676
- Year to date:
- Site-wide: 58,621
- Since beginning of last month:
- Site-wide: 115,808
Genus-wide characterization of bumblebee genomes reveals variation associated with key ecological and behavioral traits of pollinators
genomics more details view paper- Downloaded 724 times
- Download rankings, all-time:
- Site-wide: 29,313
- In genomics: 2,708
- Year to date:
- Site-wide: 18,376
- Since beginning of last month:
- Site-wide: 17,554
Evolutionary dynamics of abundant stop codon readthrough in Anopheles and Drosophila
molecular biology more details view paper- Downloaded 721 times
- Download rankings, all-time:
- Site-wide: 29,543
- In molecular biology: 839
- Year to date:
- Site-wide: 116,926
- Since beginning of last month:
- Site-wide: 36,931
RiVIERA-beta: Joint Bayesian inference of risk variants and tissue-specific epigenomic enrichments across multiple complex human diseases
bioinformatics more details view paper- Downloaded 695 times
- Download rankings, all-time:
- Site-wide: 30,979
- In bioinformatics: 3,573
- Year to date:
- Site-wide: 112,995
- Since beginning of last month:
- Site-wide: 110,859
Integrative construction of regulatory region networks in 127 human reference epigenomes by matrix factorization
epidemiology more details view paper- Downloaded 609 times
- Download rankings, all-time:
- Site-wide: 36,887
- In epidemiology: 1,726
- Year to date:
- Site-wide: 111,409
- Since beginning of last month:
- Site-wide: 121,386
Analysis of Genetically Regulated Gene Expression identifies a trauma type specific PTSD gene, SNRNP35
genetics more details view paper- Downloaded 603 times
- Download rankings, all-time:
- Site-wide: 37,327
- In genetics: 1,856
- Year to date:
- Site-wide: 93,766
- Since beginning of last month:
- Site-wide: 101,691
Evidence for secondary-variant genetic burden and non-random distribution across biological modules in a recessive ciliopathy
genetics more details view paper- Downloaded 564 times
- Download rankings, all-time:
- Site-wide: 40,623
- In genetics: 1,982
- Year to date:
- Site-wide: 47,839
- Since beginning of last month:
- Site-wide: 77,096
Plasma-derived exosomal analysis and deconvolution enables prediction and tracking of melanoma checkpoint blockade response
cancer biology more details view paper- Downloaded 563 times
- Download rankings, all-time:
- Site-wide: 40,744
- In cancer biology: 1,135
- Year to date:
- Site-wide: 43,390
- Since beginning of last month:
- Site-wide: 47,531
Correlating predicted epigenetic marks with expression data to find interactions between SNPs and genes
bioinformatics more details view paper- Downloaded 545 times
- Download rankings, all-time:
- Site-wide: 42,458
- In bioinformatics: 4,604
- Year to date:
- Site-wide: 87,444
- Since beginning of last month:
- Site-wide: 53,858
Pan-cancer screen for mutations in non-coding elements with conservation and cancer specificity reveals correlations with expression and survival
cancer biology more details view paper- Downloaded 530 times
- Download rankings, all-time:
- Site-wide: 43,938
- In cancer biology: 1,228
- Year to date:
- Site-wide: 118,855
- Since beginning of last month:
- Site-wide: 119,787
Various localized epigenetic marks predict expression across 54 samples and reveal underlying chromatin state enrichments
genetics more details view paper- Downloaded 496 times
- Download rankings, all-time:
- Site-wide: 47,456
- In genetics: 2,310
- Year to date:
- Site-wide: None
- Since beginning of last month:
- Site-wide: 113,267
Elucidation of Codon Usage Signatures across the Domains of Life
evolutionary biology more details view paper- Downloaded 479 times
- Download rankings, all-time:
- Site-wide: 49,421
- In evolutionary biology: 2,800
- Year to date:
- Site-wide: 100,850
- Since beginning of last month:
- Site-wide: 121,200
Exome-wide age-of-onset analysis reveals exonic variants in ERN1, TACR3 and SPPL2C associated with Alzheimer's disease
neuroscience more details view paper- Downloaded 461 times
- Download rankings, all-time:
- Site-wide: 51,645
- In neuroscience: 7,821
- Year to date:
- Site-wide: 74,272
- Since beginning of last month:
- Site-wide: 76,665
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