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Author: John Hardy

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  • All-time downloads: 17,916 (rank: 2,361 out of 336,478)
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    • bioinformatics: 1,060 (rank: 8,967 (tie) out of 28,921)
    • genetics: 7,346 (rank: 1,912 out of 32,490)
    • genomics: 2,302 (rank: 7,227 (tie) out of 37,022)
    • molecular biology: 231 (rank: 11,865 (tie) out of 16,774)
    • neuroscience: 6,977 (rank: 1,061 out of 56,756)

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Preprints

Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions

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G2P: Using machine learning to understand and predict genes causing rare neurological disorders

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Genetic variability in response to Aβ deposition influences Alzheimer's risk

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Genomics implicates adaptive and innate immunity in Alzheimer's and Parkinson's diseases

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Parkinson disease age of onset GWAS: defining heritability, genetic loci and a-synuclein mechanisms

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Personalized genetic assessment of age associated Alzheimers disease risk

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Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson's disease heritability

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Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

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A genome-wide genetic pleiotropy approach identified shared loci between multiple system atrophy and inflammatory bowel disease

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Integration of eQTL and Parkinson's disease GWAS data implicates 11 disease genes

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Genetic modifiers of risk and age at onset in GBA associated Parkinson disease and Lewy body dementia

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An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of a-synuclein

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Immune-related genetic enrichment in frontotemporal dementia

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Incomplete annotation of disease-associated genes is limiting our understanding of Mendelian and complex neurogenetic disorders

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Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at Chr16q11.2 and on the MAPT H1 allele.

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Heritability and genetic variance of dementia with Lewy bodies

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Gene based Analysis in HRC Imputed Genome Wide Association Data Identifies Three Novel Genes for Alzheimer's Disease

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Common variation at the LRRK2 locus is associated with survival in the primary tauopathy progressive supranuclear palsy

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The Parkinsons Disease Mendelian Randomization Research Portal

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A locked immunometabolic switch underlies TREM2 R47H loss of function in human iPSC--derived microglia

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Sequence of cognitive changes associated with development of Alzheimer's disease in Down syndrome - data driven analysis

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A comprehensive assessment of benign genetic variability for neurodegenerative disorders

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Regulatory sites for known and novel splicing in human basal ganglia are enriched for disease-relevant information

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Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene-dose-sensitive AD-suppressor in human brain

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Parkinsons disease determinants, prediction and gene-environment interactions in the UK Biobank

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ERASE: Extended Randomization for assessment of annotation enrichment in ASE datasets

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Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome

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Transcriptomic analysis of dystonia-associated genes reveals functional convergence within specific cell types and shared neurobiology with psychiatric disorders

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