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Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 60,240 bioRxiv papers from 267,843 authors.

Author: George M Church

Rankings

  • All-time downloads: 141,611 (rank: 34 out of 268,131)
  • Categories:
    • biochemistry: 2,731 (rank: 150 out of 10,286)
    • bioengineering: 5,398 (rank: 46 out of 6,537)
    • cell biology: 19,628 (rank: 1 out of 17,625)
    • evolutionary biology: 775 (rank: 4,175 (tie) out of 14,815)
    • genetics: 1,987 (rank: 5,905 (tie) out of 27,088)
    • genomics: 28,906 (rank: 189 out of 31,268)
    • immunology: 7,772 (rank: 53 (tie) out of 11,908)
    • molecular biology: 8,646 (rank: 31 out of 12,089)
    • neuroscience: 6,635 (rank: 699 (tie) out of 44,118)
    • synthetic biology: 57,809 (rank: 1 out of 2,652)
    • systems biology: 1,324 (rank: 1,180 (tie) out of 8,158)

Downloads per author, site-wide

Preprints

Vibrio natriegens, a new genomic powerhouse

genomics more details view paper
  • Downloaded 14,818 times
  • Download rankings, all-time:
    • Site-wide: 44 out of 60,323
    • In genomics: 12 out of 4,185
  • Year to date:
    • Site-wide: 367 out of 60,323
  • Since beginning of last month:
    • Site-wide: 730 out of 60,323

Inter-homologue repair in fertilized human eggs?

cell biology more details view paper
  • Downloaded 9,853 times
  • Download rankings, all-time:
    • Site-wide: 105 out of 60,323
    • In cell biology: 4 out of 2,870
  • Year to date:
    • Site-wide: 14,010 out of 60,323
  • Since beginning of last month:
    • Site-wide: 17,799 out of 60,323

Tumor-infiltrating immune repertoires captured by single-cell barcoding in emulsion

immunology more details view paper
  • Downloaded 6,071 times
  • Download rankings, all-time:
    • Site-wide: 271 out of 60,323
    • In immunology: 4 out of 1,481
  • Year to date:
    • Site-wide: 3,915 out of 60,323
  • Since beginning of last month:
    • Site-wide: 8,947 out of 60,323

Conneconomics: The Economics of Dense, Large-Scale, High-Resolution Neural Connectomics

neuroscience more details view paper
  • Downloaded 5,986 times
  • Download rankings, all-time:
    • Site-wide: 281 out of 60,323
    • In neuroscience: 41 out of 10,669
  • Year to date:
    • Site-wide: 5,871 out of 60,323
  • Since beginning of last month:
    • Site-wide: 13,301 out of 60,323

Reversal of ageing- and injury-induced vision loss by Tet-dependent epigenetic reprogramming

molecular biology more details view paper
  • Downloaded 5,859 times
  • Download rankings, all-time:
    • Site-wide: 293 out of 60,323
    • In molecular biology: 6 out of 1,864
  • Year to date:
    • Site-wide: 46 out of 60,323
  • Since beginning of last month:
    • Site-wide: 3 out of 60,323

Rapidly evolving homing CRISPR barcodes

synthetic biology more details view paper
  • Downloaded 5,796 times
  • Download rankings, all-time:
    • Site-wide: 304 out of 60,323
    • In synthetic biology: 6 out of 576
  • Year to date:
    • Site-wide: 16,842 out of 60,323
  • Since beginning of last month:
    • Site-wide: 24,653 out of 60,323

Extensive sequencing of seven human genomes to characterize benchmark reference materials

genomics more details view paper
  • Downloaded 5,736 times
  • Download rankings, all-time:
    • Site-wide: 309 out of 60,323
    • In genomics: 83 out of 4,185
  • Year to date:
    • Site-wide: 16,762 out of 60,323
  • Since beginning of last month:
    • Site-wide: 16,534 out of 60,323

Highly-efficient Cas9-mediated transcriptional programming

synthetic biology more details view paper
  • Downloaded 5,521 times
  • Download rankings, all-time:
    • Site-wide: 329 out of 60,323
    • In synthetic biology: 7 out of 576
  • Year to date:
    • Site-wide: 15,274 out of 60,323
  • Since beginning of last month:
    • Site-wide: 11,484 out of 60,323

Daisy-chain gene drives for the alteration of local populations

synthetic biology more details view paper
  • Downloaded 4,985 times
  • Download rankings, all-time:
    • Site-wide: 384 out of 60,323
    • In synthetic biology: 8 out of 576
  • Year to date:
    • Site-wide: 2,116 out of 60,323
  • Since beginning of last month:
    • Site-wide: 8,106 out of 60,323

Enabling large-scale genome editing by reducing DNA nicking

synthetic biology more details view paper
  • Downloaded 4,886 times
  • Download rankings, all-time:
    • Site-wide: 399 out of 60,323
    • In synthetic biology: 9 out of 576
  • Year to date:
    • Site-wide: 59 out of 60,323
  • Since beginning of last month:
    • Site-wide: 2,394 out of 60,323

Unified rational protein engineering with sequence-only deep representation learning

synthetic biology more details view paper
  • Downloaded 4,674 times
  • Download rankings, all-time:
    • Site-wide: 440 out of 60,323
    • In synthetic biology: 10 out of 576
  • Year to date:
    • Site-wide: 66 out of 60,323
  • Since beginning of last month:
    • Site-wide: 92 out of 60,323

Highly multiplexed in situ protein imaging with signal amplification by Immuno-SABER

cell biology more details view paper
  • Downloaded 4,584 times
  • Download rankings, all-time:
    • Site-wide: 454 out of 60,323
    • In cell biology: 10 out of 2,870
  • Year to date:
    • Site-wide: 98 out of 60,323
  • Since beginning of last month:
    • Site-wide: 363 out of 60,323

Toward machine-guided design of proteins

synthetic biology more details view paper
  • Downloaded 4,534 times
  • Download rankings, all-time:
    • Site-wide: 462 out of 60,323
    • In synthetic biology: 11 out of 576
  • Year to date:
    • Site-wide: 354 out of 60,323
  • Since beginning of last month:
    • Site-wide: 604 out of 60,323

CasFinder: Flexible algorithm for identifying specific Cas9 targets in genomes

genomics more details view paper
  • Downloaded 4,391 times
  • Download rankings, all-time:
    • Site-wide: 504 out of 60,323
    • In genomics: 133 out of 4,185
  • Year to date:
    • Site-wide: 7,341 out of 60,323
  • Since beginning of last month:
    • Site-wide: 9,291 out of 60,323

Enzymatic DNA synthesis for digital information storage

synthetic biology more details view paper
  • Downloaded 4,100 times
  • Download rankings, all-time:
    • Site-wide: 576 out of 60,323
    • In synthetic biology: 12 out of 576
  • Year to date:
    • Site-wide: 526 out of 60,323
  • Since beginning of last month:
    • Site-wide: 3,727 out of 60,323

Barcoded oligonucleotides ligated on RNA amplified for multiplex and parallel in-situ analyses

cell biology more details view paper
  • Downloaded 3,751 times
  • Download rankings, all-time:
    • Site-wide: 689 out of 60,323
    • In cell biology: 21 out of 2,870
  • Year to date:
    • Site-wide: 982 out of 60,323
  • Since beginning of last month:
    • Site-wide: 1,407 out of 60,323

Current CRISPR gene drive systems are likely to be highly invasive in wild populations

synthetic biology more details view paper
  • Downloaded 3,686 times
  • Download rankings, all-time:
    • Site-wide: 711 out of 60,323
    • In synthetic biology: 15 out of 576
  • Year to date:
    • Site-wide: 13,907 out of 60,323
  • Since beginning of last month:
    • Site-wide: 20,390 out of 60,323

A homing CRISPR mouse resource for barcoding and lineage tracing

synthetic biology more details view paper
  • Downloaded 2,986 times
  • Download rankings, all-time:
    • Site-wide: 1,046 out of 60,323
    • In synthetic biology: 21 out of 576
  • Year to date:
    • Site-wide: 8,183 out of 60,323
  • Since beginning of last month:
    • Site-wide: 15,197 out of 60,323

Rapid Sequential In Situ Multiplexing With DNA-Exchange-Imaging

bioengineering more details view paper
  • Downloaded 2,984 times
  • Download rankings, all-time:
    • Site-wide: 1,049 out of 60,323
    • In bioengineering: 14 out of 1,175
  • Year to date:
    • Site-wide: 23,114 out of 60,323
  • Since beginning of last month:
    • Site-wide: 24,436 out of 60,323

Evolutionary dynamics of CRISPR gene drives

synthetic biology more details view paper
  • Downloaded 2,497 times
  • Download rankings, all-time:
    • Site-wide: 1,430 out of 60,323
    • In synthetic biology: 26 out of 576
  • Year to date:
    • Site-wide: 30,153 out of 60,323
  • Since beginning of last month:
    • Site-wide: 33,491 out of 60,323

Precise Cas9 targeting enables genomic mutation prevention

synthetic biology more details view paper
  • Downloaded 2,429 times
  • Download rankings, all-time:
    • Site-wide: 1,526 out of 60,323
    • In synthetic biology: 27 out of 576
  • Year to date:
    • Site-wide: 33,309 out of 60,323
  • Since beginning of last month:
    • Site-wide: 35,497 out of 60,323

Assembly of Radically Recoded E. coli Genome Segments

synthetic biology more details view paper
  • Downloaded 2,349 times
  • Download rankings, all-time:
    • Site-wide: 1,625 out of 60,323
    • In synthetic biology: 29 out of 576
  • Year to date:
    • Site-wide: 16,111 out of 60,323
  • Since beginning of last month:
    • Site-wide: 24,282 out of 60,323

Recombineering in Vibrio natriegens

synthetic biology more details view paper
  • Downloaded 2,074 times
  • Download rankings, all-time:
    • Site-wide: 2,001 out of 60,323
    • In synthetic biology: 37 out of 576
  • Year to date:
    • Site-wide: 5,131 out of 60,323
  • Since beginning of last month:
    • Site-wide: 8,733 out of 60,323

The experimental design and data interpretation in ‘Unexpected mutations after CRISPR Cas9 editing in vivo’ by Schaefer et al. are insufficient to support the conclusions drawn by the authors

genetics more details view paper
  • Downloaded 1,987 times
  • Download rankings, all-time:
    • Site-wide: 2,187 out of 60,323
    • In genetics: 213 out of 3,443
  • Year to date:
    • Site-wide: 31,974 out of 60,323
  • Since beginning of last month:
    • Site-wide: 36,711 out of 60,323

Single-cell sequencing reveals αβ chain pairing shapes the T cell repertoire

immunology more details view paper
  • Downloaded 1,701 times
  • Download rankings, all-time:
    • Site-wide: 2,847 out of 60,323
    • In immunology: 32 out of 1,481
  • Year to date:
    • Site-wide: 8,115 out of 60,323
  • Since beginning of last month:
    • Site-wide: 6,154 out of 60,323

Efficient in situ barcode sequencing using padlock probe-based BaristaSeq

molecular biology more details view paper
  • Downloaded 1,560 times
  • Download rankings, all-time:
    • Site-wide: 3,275 out of 60,323
    • In molecular biology: 93 out of 1,864
  • Year to date:
    • Site-wide: 16,291 out of 60,323
  • Since beginning of last month:
    • Site-wide: 15,267 out of 60,323

High-throughput creation and functional profiling of eukaryotic DNA sequence variant libraries using CRISPR/Cas9

bioengineering more details view paper
  • Downloaded 1,556 times
  • Download rankings, all-time:
    • Site-wide: 3,289 out of 60,323
    • In bioengineering: 54 out of 1,175
  • Year to date:
    • Site-wide: 23,106 out of 60,323
  • Since beginning of last month:
    • Site-wide: 25,450 out of 60,323

Multiplexed imaging using same species primary antibodies with signal amplification

cell biology more details view paper
  • Downloaded 1,440 times
  • Download rankings, all-time:
    • Site-wide: 3,765 out of 60,323
    • In cell biology: 104 out of 2,870
  • Year to date:
    • Site-wide: 5,615 out of 60,323
  • Since beginning of last month:
    • Site-wide: 9,904 out of 60,323

A systematic comparison of error correction enzymes by next-generation sequencing

synthetic biology more details view paper
  • Downloaded 1,315 times
  • Download rankings, all-time:
    • Site-wide: 4,360 out of 60,323
    • In synthetic biology: 65 out of 576
  • Year to date:
    • Site-wide: 23,638 out of 60,323
  • Since beginning of last month:
    • Site-wide: 17,581 out of 60,323

Concerning RNA-Guided Gene Drives for the Alteration of Wild Populations

synthetic biology more details view paper
  • Downloaded 1,294 times
  • Download rankings, all-time:
    • Site-wide: 4,488 out of 60,323
    • In synthetic biology: 67 out of 576
  • Year to date:
    • Site-wide: 41,280 out of 60,323
  • Since beginning of last month:
    • Site-wide: 46,769 out of 60,323

Enhanced bacterial immunity and mammalian genome editing via RNA polymerase-mediated dislodging of Cas9 from double strand DNA breaks.

molecular biology more details view paper
  • Downloaded 1,227 times
  • Download rankings, all-time:
    • Site-wide: 4,861 out of 60,323
    • In molecular biology: 143 out of 1,864
  • Year to date:
    • Site-wide: 16,269 out of 60,323
  • Since beginning of last month:
    • Site-wide: 28,885 out of 60,323

Reprogramming protein kinase substrate specificity through synthetic mutations

biochemistry more details view paper
  • Downloaded 1,216 times
  • Download rankings, all-time:
    • Site-wide: 4,932 out of 60,323
    • In biochemistry: 92 out of 1,748
  • Year to date:
    • Site-wide: 25,241 out of 60,323
  • Since beginning of last month:
    • Site-wide: 14,293 out of 60,323

The whale shark genome reveals how genomic and physiological properties scale with body size

genomics more details view paper
  • Downloaded 1,100 times
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    • Site-wide: 5,858 out of 60,323
    • In genomics: 982 out of 4,185
  • Year to date:
    • Site-wide: 3,785 out of 60,323
  • Since beginning of last month:
    • Site-wide: 3,745 out of 60,323

Engineering post-translational proofreading to discriminate non-standard amino acids

synthetic biology more details view paper
  • Downloaded 1,087 times
  • Download rankings, all-time:
    • Site-wide: 5,984 out of 60,323
    • In synthetic biology: 93 out of 576
  • Year to date:
    • Site-wide: 29,632 out of 60,323
  • Since beginning of last month:
    • Site-wide: 30,578 out of 60,323

Circularization of genes and chromosome by CRISPR in human cells

genomics more details view paper
  • Downloaded 1,073 times
  • Download rankings, all-time:
    • Site-wide: 6,119 out of 60,323
    • In genomics: 1,022 out of 4,185
  • Year to date:
    • Site-wide: 20,608 out of 60,323
  • Since beginning of last month:
    • Site-wide: 37,944 out of 60,323

Optimizing complex phenotypes through model-guided multiplex genome engineering

synthetic biology more details view paper
  • Downloaded 1,065 times
  • Download rankings, all-time:
    • Site-wide: 6,199 out of 60,323
    • In synthetic biology: 95 out of 576
  • Year to date:
    • Site-wide: 42,932 out of 60,323
  • Since beginning of last month:
    • Site-wide: 55,223 out of 60,323

Establishing a cell-free Vibrio natriegens expression system

synthetic biology more details view paper
  • Downloaded 1,011 times
  • Download rankings, all-time:
    • Site-wide: 6,736 out of 60,323
    • In synthetic biology: 104 out of 576
  • Year to date:
    • Site-wide: 13,099 out of 60,323
  • Since beginning of last month:
    • Site-wide: 20,082 out of 60,323

Biosensor libraries harness large classes of binding domains for allosteric transcription regulators

synthetic biology more details view paper
  • Downloaded 968 times
  • Download rankings, all-time:
    • Site-wide: 7,198 out of 60,323
    • In synthetic biology: 114 out of 576
  • Year to date:
    • Site-wide: 39,080 out of 60,323
  • Since beginning of last month:
    • Site-wide: 47,238 out of 60,323

Systemic post-translational control of bacterial metabolism regulates adaptation in dynamic environments

systems biology more details view paper
  • Downloaded 909 times
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    • Site-wide: 7,953 out of 60,323
    • In systems biology: 220 out of 1,713
  • Year to date:
    • Site-wide: 13,572 out of 60,323
  • Since beginning of last month:
    • Site-wide: 10,517 out of 60,323

Dissecting limiting factors of the Protein synthesis Using Recombinant Elements (PURE) system

bioengineering more details view paper
  • Downloaded 858 times
  • Download rankings, all-time:
    • Site-wide: 8,703 out of 60,323
    • In bioengineering: 148 out of 1,175
  • Year to date:
    • Site-wide: 57,867 out of 60,323
  • Since beginning of last month:
    • Site-wide: 52,126 out of 60,323

Long-term adaptive evolution of genomically recoded Escherichia coli

evolutionary biology more details view paper
  • Downloaded 775 times
  • Download rankings, all-time:
    • Site-wide: 10,170 out of 60,323
    • In evolutionary biology: 687 out of 4,114
  • Year to date:
    • Site-wide: 51,299 out of 60,323
  • Since beginning of last month:
    • Site-wide: 45,585 out of 60,323

Ethnically relevant consensus Korean reference genome towards personal reference genomes

genomics more details view paper
  • Downloaded 691 times
  • Download rankings, all-time:
    • Site-wide: 12,010 out of 60,323
    • In genomics: 1,673 out of 4,185
  • Year to date:
    • Site-wide: 47,867 out of 60,323
  • Since beginning of last month:
    • Site-wide: 52,806 out of 60,323

Significant abundance of cis configurations of mutations in diploid human genomes

genomics more details view paper
  • Downloaded 655 times
  • Download rankings, all-time:
    • Site-wide: 12,925 out of 60,323
    • In genomics: 1,770 out of 4,185
  • Year to date:
    • Site-wide: 15,556 out of 60,323
  • Since beginning of last month:
    • Site-wide: 13,287 out of 60,323

Spatial Information in Large-Scale Neural Recordings

neuroscience more details view paper
  • Downloaded 649 times
  • Download rankings, all-time:
    • Site-wide: 13,090 out of 60,323
    • In neuroscience: 2,109 out of 10,669
  • Year to date:
    • Site-wide: 55,535 out of 60,323
  • Since beginning of last month:
    • Site-wide: 57,379 out of 60,323

Cushing's Syndrome mutant PKAL205R exhibits altered substrate specificity

biochemistry more details view paper
  • Downloaded 599 times
  • Download rankings, all-time:
    • Site-wide: 14,604 out of 60,323
    • In biochemistry: 295 out of 1,748
  • Year to date:
    • Site-wide: 44,066 out of 60,323
  • Since beginning of last month:
    • Site-wide: 38,702 out of 60,323

Toward D-Peptide Biosynthesis: Elongation Factor P Enables Ribosomal Incorporation Of Consecutive D-Amino Acids

biochemistry more details view paper
  • Downloaded 588 times
  • Download rankings, all-time:
    • Site-wide: 14,999 out of 60,323
    • In biochemistry: 305 out of 1,748
  • Year to date:
    • Site-wide: 38,311 out of 60,323
  • Since beginning of last month:
    • Site-wide: 38,334 out of 60,323

Millstone: Software for Multiplex Microbial Genome Analysis and Engineering

synthetic biology more details view paper
  • Downloaded 552 times
  • Download rankings, all-time:
    • Site-wide: 16,285 out of 60,323
    • In synthetic biology: 265 out of 576
  • Year to date:
    • Site-wide: 43,681 out of 60,323
  • Since beginning of last month:
    • Site-wide: 42,682 out of 60,323

Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli

genomics more details view paper
  • Downloaded 442 times
  • Download rankings, all-time:
    • Site-wide: 21,406 out of 60,323
    • In genomics: 2,407 out of 4,185
  • Year to date:
    • Site-wide: 53,097 out of 60,323
  • Since beginning of last month:
    • Site-wide: 56,800 out of 60,323

Simulating serial-target antibacterial drug synergies using flux balance analysis

systems biology more details view paper
  • Downloaded 415 times
  • Download rankings, all-time:
    • Site-wide: 22,950 out of 60,323
    • In systems biology: 701 out of 1,713
  • Year to date:
    • Site-wide: 58,235 out of 60,323
  • Since beginning of last month:
    • Site-wide: 57,606 out of 60,323

Physiological Assembly Of Functionally Active 30S Ribosomal Subunits From In Vitro Synthesized Parts

biochemistry more details view paper
  • Downloaded 328 times
  • Download rankings, all-time:
    • Site-wide: 29,150 out of 60,323
    • In biochemistry: 723 out of 1,748
  • Year to date:
    • Site-wide: 51,585 out of 60,323
  • Since beginning of last month:
    • Site-wide: 42,160 out of 60,323

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