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Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 67,118 bioRxiv papers from 295,271 authors.

Author: George M Church

Rankings

  • All-time downloads: 153,163 (rank: 33 out of 295,131)
  • Categories:
    • biochemistry: 2,819 (rank: 179 out of 11,610)
    • bioengineering: 5,480 (rank: 46 out of 7,476)
    • bioinformatics: 1,475 (rank: 5,446 (tie) out of 25,701)
    • cell biology: 20,404 (rank: 1 out of 19,926)
    • evolutionary biology: 792 (rank: 4,579 (tie) out of 16,096)
    • genetics: 2,014 (rank: 6,391 (tie) out of 29,432)
    • genomics: 30,269 (rank: 189 out of 33,598)
    • immunology: 7,966 (rank: 56 (tie) out of 13,871)
    • molecular biology: 11,611 (rank: 30 out of 14,193)
    • neuroscience: 6,782 (rank: 809 (tie) out of 49,431)
    • synthetic biology: 62,184 (rank: 1 out of 2,923)
    • systems biology: 1,367 (rank: 1,355 out of 8,899)

Downloads per author, site-wide

Preprints

Vibrio natriegens, a new genomic powerhouse

genomics more details view paper
  • Downloaded 15,404 times
  • Download rankings, all-time:
    • Site-wide: 48 out of 67,044
    • In genomics: 12 out of 4,558
  • Year to date:
    • Site-wide: 328 out of 67,044
  • Since beginning of last month:
    • Site-wide: 1,304 out of 67,044

Inter-homologue repair in fertilized human eggs?

cell biology more details view paper
  • Downloaded 9,968 times
  • Download rankings, all-time:
    • Site-wide: 118 out of 67,044
    • In cell biology: 4 out of 3,248
  • Year to date:
    • Site-wide: 11,184 out of 67,044
  • Since beginning of last month:
    • Site-wide: 7,981 out of 67,044

Reversal of ageing- and injury-induced vision loss by Tet-dependent epigenetic reprogramming

molecular biology more details view paper
  • Downloaded 8,777 times
  • Download rankings, all-time:
    • Site-wide: 153 out of 67,044
    • In molecular biology: 5 out of 2,139
  • Year to date:
    • Site-wide: 31 out of 67,044
  • Since beginning of last month:
    • Site-wide: 59 out of 67,044

Unified rational protein engineering with sequence-only deep representation learning

synthetic biology more details view paper
  • Downloaded 6,580 times
  • Download rankings, all-time:
    • Site-wide: 268 out of 67,044
    • In synthetic biology: 6 out of 638
  • Year to date:
    • Site-wide: 60 out of 67,044
  • Since beginning of last month:
    • Site-wide: 257 out of 67,044

Tumor-infiltrating immune repertoires captured by single-cell barcoding in emulsion

immunology more details view paper
  • Downloaded 6,173 times
  • Download rankings, all-time:
    • Site-wide: 304 out of 67,044
    • In immunology: 4 out of 1,706
  • Year to date:
    • Site-wide: 4,259 out of 67,044
  • Since beginning of last month:
    • Site-wide: 5,936 out of 67,044

Conneconomics: The Economics of Dense, Large-Scale, High-Resolution Neural Connectomics

neuroscience more details view paper
  • Downloaded 6,117 times
  • Download rankings, all-time:
    • Site-wide: 309 out of 67,044
    • In neuroscience: 45 out of 12,017
  • Year to date:
    • Site-wide: 5,470 out of 67,044
  • Since beginning of last month:
    • Site-wide: 6,006 out of 67,044

Rapidly evolving homing CRISPR barcodes

synthetic biology more details view paper
  • Downloaded 5,846 times
  • Download rankings, all-time:
    • Site-wide: 333 out of 67,044
    • In synthetic biology: 7 out of 638
  • Year to date:
    • Site-wide: 17,809 out of 67,044
  • Since beginning of last month:
    • Site-wide: 22,074 out of 67,044

Extensive sequencing of seven human genomes to characterize benchmark reference materials

genomics more details view paper
  • Downloaded 5,789 times
  • Download rankings, all-time:
    • Site-wide: 342 out of 67,044
    • In genomics: 87 out of 4,558
  • Year to date:
    • Site-wide: 17,444 out of 67,044
  • Since beginning of last month:
    • Site-wide: 22,487 out of 67,044

Highly-efficient Cas9-mediated transcriptional programming

synthetic biology more details view paper
  • Downloaded 5,563 times
  • Download rankings, all-time:
    • Site-wide: 361 out of 67,044
    • In synthetic biology: 8 out of 638
  • Year to date:
    • Site-wide: 17,047 out of 67,044
  • Since beginning of last month:
    • Site-wide: 42,167 out of 67,044

Enabling large-scale genome editing by reducing DNA nicking

synthetic biology more details view paper
  • Downloaded 5,192 times
  • Download rankings, all-time:
    • Site-wide: 406 out of 67,044
    • In synthetic biology: 9 out of 638
  • Year to date:
    • Site-wide: 86 out of 67,044
  • Since beginning of last month:
    • Site-wide: 1,809 out of 67,044

Daisy-chain gene drives for the alteration of local populations

synthetic biology more details view paper
  • Downloaded 5,055 times
  • Download rankings, all-time:
    • Site-wide: 425 out of 67,044
    • In synthetic biology: 11 out of 638
  • Year to date:
    • Site-wide: 2,656 out of 67,044
  • Since beginning of last month:
    • Site-wide: 14,371 out of 67,044

Toward machine-guided design of proteins

synthetic biology more details view paper
  • Downloaded 4,953 times
  • Download rankings, all-time:
    • Site-wide: 439 out of 67,044
    • In synthetic biology: 12 out of 638
  • Year to date:
    • Site-wide: 375 out of 67,044
  • Since beginning of last month:
    • Site-wide: 1,317 out of 67,044

Highly multiplexed in situ protein imaging with signal amplification by Immuno-SABER

cell biology more details view paper
  • Downloaded 4,881 times
  • Download rankings, all-time:
    • Site-wide: 454 out of 67,044
    • In cell biology: 9 out of 3,248
  • Year to date:
    • Site-wide: 126 out of 67,044
  • Since beginning of last month:
    • Site-wide: 4,427 out of 67,044

CasFinder: Flexible algorithm for identifying specific Cas9 targets in genomes

genomics more details view paper
  • Downloaded 4,499 times
  • Download rankings, all-time:
    • Site-wide: 537 out of 67,044
    • In genomics: 142 out of 4,558
  • Year to date:
    • Site-wide: 6,988 out of 67,044
  • Since beginning of last month:
    • Site-wide: 5,912 out of 67,044

Enzymatic DNA synthesis for digital information storage

synthetic biology more details view paper
  • Downloaded 4,275 times
  • Download rankings, all-time:
    • Site-wide: 601 out of 67,044
    • In synthetic biology: 13 out of 638
  • Year to date:
    • Site-wide: 658 out of 67,044
  • Since beginning of last month:
    • Site-wide: 5,875 out of 67,044

Barcoded oligonucleotides ligated on RNA amplified for multiplex and parallel in-situ analyses

cell biology more details view paper
  • Downloaded 4,003 times
  • Download rankings, all-time:
    • Site-wide: 678 out of 67,044
    • In cell biology: 23 out of 3,248
  • Year to date:
    • Site-wide: 1,002 out of 67,044
  • Since beginning of last month:
    • Site-wide: 2,710 out of 67,044

Current CRISPR gene drive systems are likely to be highly invasive in wild populations

synthetic biology more details view paper
  • Downloaded 3,731 times
  • Download rankings, all-time:
    • Site-wide: 780 out of 67,044
    • In synthetic biology: 16 out of 638
  • Year to date:
    • Site-wide: 15,444 out of 67,044
  • Since beginning of last month:
    • Site-wide: 27,239 out of 67,044

A homing CRISPR mouse resource for barcoding and lineage tracing

synthetic biology more details view paper
  • Downloaded 3,040 times
  • Download rankings, all-time:
    • Site-wide: 1,150 out of 67,044
    • In synthetic biology: 22 out of 638
  • Year to date:
    • Site-wide: 9,454 out of 67,044
  • Since beginning of last month:
    • Site-wide: 15,680 out of 67,044

Rapid Sequential In Situ Multiplexing With DNA-Exchange-Imaging

bioengineering more details view paper
  • Downloaded 3,013 times
  • Download rankings, all-time:
    • Site-wide: 1,169 out of 67,044
    • In bioengineering: 15 out of 1,345
  • Year to date:
    • Site-wide: 26,469 out of 67,044
  • Since beginning of last month:
    • Site-wide: 37,613 out of 67,044

Evolutionary dynamics of CRISPR gene drives

synthetic biology more details view paper
  • Downloaded 2,520 times
  • Download rankings, all-time:
    • Site-wide: 1,599 out of 67,044
    • In synthetic biology: 28 out of 638
  • Year to date:
    • Site-wide: 34,547 out of 67,044
  • Since beginning of last month:
    • Site-wide: 59,597 out of 67,044

Precise Cas9 targeting enables genomic mutation prevention

synthetic biology more details view paper
  • Downloaded 2,447 times
  • Download rankings, all-time:
    • Site-wide: 1,697 out of 67,044
    • In synthetic biology: 29 out of 638
  • Year to date:
    • Site-wide: 39,106 out of 67,044
  • Since beginning of last month:
    • Site-wide: 52,264 out of 67,044

Assembly of Radically Recoded E. coli Genome Segments

synthetic biology more details view paper
  • Downloaded 2,390 times
  • Download rankings, all-time:
    • Site-wide: 1,773 out of 67,044
    • In synthetic biology: 33 out of 638
  • Year to date:
    • Site-wide: 17,976 out of 67,044
  • Since beginning of last month:
    • Site-wide: 32,146 out of 67,044

Recombineering in Vibrio natriegens

synthetic biology more details view paper
  • Downloaded 2,145 times
  • Download rankings, all-time:
    • Site-wide: 2,149 out of 67,044
    • In synthetic biology: 39 out of 638
  • Year to date:
    • Site-wide: 5,887 out of 67,044
  • Since beginning of last month:
    • Site-wide: 16,241 out of 67,044

The experimental design and data interpretation in ‘Unexpected mutations after CRISPR Cas9 editing in vivo’ by Schaefer et al. are insufficient to support the conclusions drawn by the authors

genetics more details view paper
  • Downloaded 2,014 times
  • Download rankings, all-time:
    • Site-wide: 2,403 out of 67,044
    • In genetics: 223 out of 3,773
  • Year to date:
    • Site-wide: 35,478 out of 67,044
  • Since beginning of last month:
    • Site-wide: 38,860 out of 67,044

Single-cell sequencing reveals αβ chain pairing shapes the T cell repertoire

immunology more details view paper
  • Downloaded 1,793 times
  • Download rankings, all-time:
    • Site-wide: 2,905 out of 67,044
    • In immunology: 39 out of 1,706
  • Year to date:
    • Site-wide: 8,037 out of 67,044
  • Since beginning of last month:
    • Site-wide: 8,911 out of 67,044

High-throughput creation and functional profiling of eukaryotic DNA sequence variant libraries using CRISPR/Cas9

bioengineering more details view paper
  • Downloaded 1,600 times
  • Download rankings, all-time:
    • Site-wide: 3,527 out of 67,044
    • In bioengineering: 58 out of 1,345
  • Year to date:
    • Site-wide: 24,153 out of 67,044
  • Since beginning of last month:
    • Site-wide: 21,800 out of 67,044

Efficient in situ barcode sequencing using padlock probe-based BaristaSeq

molecular biology more details view paper
  • Downloaded 1,593 times
  • Download rankings, all-time:
    • Site-wide: 3,549 out of 67,044
    • In molecular biology: 101 out of 2,139
  • Year to date:
    • Site-wide: 18,930 out of 67,044
  • Since beginning of last month:
    • Site-wide: 61,133 out of 67,044

Multiplexed imaging using same species primary antibodies with signal amplification

cell biology more details view paper
  • Downloaded 1,552 times
  • Download rankings, all-time:
    • Site-wide: 3,716 out of 67,044
    • In cell biology: 103 out of 3,248
  • Year to date:
    • Site-wide: 5,583 out of 67,044
  • Since beginning of last month:
    • Site-wide: 20,715 out of 67,044

Efficient chromosome-scale haplotype-resolved assembly of human genomes

bioinformatics more details view paper
  • Downloaded 1,475 times
  • Download rankings, all-time:
    • Site-wide: 4,073 out of 67,044
    • In bioinformatics: 803 out of 6,614
  • Year to date:
    • Site-wide: 955 out of 67,044
  • Since beginning of last month:
    • Site-wide: 233 out of 67,044

A systematic comparison of error correction enzymes by next-generation sequencing

synthetic biology more details view paper
  • Downloaded 1,365 times
  • Download rankings, all-time:
    • Site-wide: 4,622 out of 67,044
    • In synthetic biology: 68 out of 638
  • Year to date:
    • Site-wide: 23,620 out of 67,044
  • Since beginning of last month:
    • Site-wide: 23,577 out of 67,044

Concerning RNA-Guided Gene Drives for the Alteration of Wild Populations

synthetic biology more details view paper
  • Downloaded 1,309 times
  • Download rankings, all-time:
    • Site-wide: 4,932 out of 67,044
    • In synthetic biology: 71 out of 638
  • Year to date:
    • Site-wide: 48,104 out of 67,044
  • Since beginning of last month:
    • Site-wide: 56,031 out of 67,044

Reprogramming protein kinase substrate specificity through synthetic mutations

biochemistry more details view paper
  • Downloaded 1,248 times
  • Download rankings, all-time:
    • Site-wide: 5,340 out of 67,044
    • In biochemistry: 102 out of 1,974
  • Year to date:
    • Site-wide: 27,951 out of 67,044
  • Since beginning of last month:
    • Site-wide: 23,834 out of 67,044

Enhanced bacterial immunity and mammalian genome editing via RNA polymerase-mediated dislodging of Cas9 from double strand DNA breaks.

molecular biology more details view paper
  • Downloaded 1,241 times
  • Download rankings, all-time:
    • Site-wide: 5,395 out of 67,044
    • In molecular biology: 166 out of 2,139
  • Year to date:
    • Site-wide: 21,112 out of 67,044
  • Since beginning of last month:
    • Site-wide: 46,982 out of 67,044

The whale shark genome reveals how genomic and physiological properties scale with body size

genomics more details view paper
  • Downloaded 1,197 times
  • Download rankings, all-time:
    • Site-wide: 5,716 out of 67,044
    • In genomics: 968 out of 4,558
  • Year to date:
    • Site-wide: 4,193 out of 67,044
  • Since beginning of last month:
    • Site-wide: 18,890 out of 67,044

Engineering post-translational proofreading to discriminate non-standard amino acids

synthetic biology more details view paper
  • Downloaded 1,101 times
  • Download rankings, all-time:
    • Site-wide: 6,592 out of 67,044
    • In synthetic biology: 100 out of 638
  • Year to date:
    • Site-wide: 36,118 out of 67,044
  • Since beginning of last month:
    • Site-wide: 60,485 out of 67,044

Establishing a cell-free Vibrio natriegens expression system

synthetic biology more details view paper
  • Downloaded 1,100 times
  • Download rankings, all-time:
    • Site-wide: 6,614 out of 67,044
    • In synthetic biology: 101 out of 638
  • Year to date:
    • Site-wide: 11,920 out of 67,044
  • Since beginning of last month:
    • Site-wide: 32,596 out of 67,044

Circularization of genes and chromosome by CRISPR in human cells

genomics more details view paper
  • Downloaded 1,094 times
  • Download rankings, all-time:
    • Site-wide: 6,666 out of 67,044
    • In genomics: 1,091 out of 4,558
  • Year to date:
    • Site-wide: 25,089 out of 67,044
  • Since beginning of last month:
    • Site-wide: 38,726 out of 67,044

Optimizing complex phenotypes through model-guided multiplex genome engineering

synthetic biology more details view paper
  • Downloaded 1,084 times
  • Download rankings, all-time:
    • Site-wide: 6,793 out of 67,044
    • In synthetic biology: 103 out of 638
  • Year to date:
    • Site-wide: 48,190 out of 67,044
  • Since beginning of last month:
    • Site-wide: 64,400 out of 67,044

Biosensor libraries harness large classes of binding domains for allosteric transcription regulators

synthetic biology more details view paper
  • Downloaded 992 times
  • Download rankings, all-time:
    • Site-wide: 7,809 out of 67,044
    • In synthetic biology: 124 out of 638
  • Year to date:
    • Site-wide: 43,019 out of 67,044
  • Since beginning of last month:
    • Site-wide: 41,101 out of 67,044

Systemic post-translational control of bacterial metabolism regulates adaptation in dynamic environments

systems biology more details view paper
  • Downloaded 941 times
  • Download rankings, all-time:
    • Site-wide: 8,525 out of 67,044
    • In systems biology: 238 out of 1,863
  • Year to date:
    • Site-wide: 16,191 out of 67,044
  • Since beginning of last month:
    • Site-wide: 33,758 out of 67,044

Dissecting limiting factors of the Protein synthesis Using Recombinant Elements (PURE) system

bioengineering more details view paper
  • Downloaded 867 times
  • Download rankings, all-time:
    • Site-wide: 9,676 out of 67,044
    • In bioengineering: 166 out of 1,345
  • Year to date:
    • Site-wide: 64,871 out of 67,044
  • Since beginning of last month:
    • Site-wide: 56,795 out of 67,044

Long-term adaptive evolution of genomically recoded Escherichia coli

evolutionary biology more details view paper
  • Downloaded 792 times
  • Download rankings, all-time:
    • Site-wide: 11,123 out of 67,044
    • In evolutionary biology: 741 out of 4,461
  • Year to date:
    • Site-wide: 56,788 out of 67,044
  • Since beginning of last month:
    • Site-wide: 59,791 out of 67,044

Significant abundance of cis configurations of mutations in diploid human genomes

genomics more details view paper
  • Downloaded 739 times
  • Download rankings, all-time:
    • Site-wide: 12,309 out of 67,044
    • In genomics: 1,717 out of 4,558
  • Year to date:
    • Site-wide: 13,985 out of 67,044
  • Since beginning of last month:
    • Site-wide: 21,068 out of 67,044

Genetic design automation for autonomous formation of multicellular shapes from a single cell progenitor

synthetic biology more details view paper
  • Downloaded 735 times
  • Download rankings, all-time:
    • Site-wide: 12,406 out of 67,044
    • In synthetic biology: 206 out of 638
  • Year to date:
    • Site-wide: 3,317 out of 67,044
  • Since beginning of last month:
    • Site-wide: 1,045 out of 67,044

Ethnically relevant consensus Korean reference genome towards personal reference genomes

genomics more details view paper
  • Downloaded 708 times
  • Download rankings, all-time:
    • Site-wide: 13,120 out of 67,044
    • In genomics: 1,794 out of 4,558
  • Year to date:
    • Site-wide: 53,493 out of 67,044
  • Since beginning of last month:
    • Site-wide: 40,854 out of 67,044

Spatial Information in Large-Scale Neural Recordings

neuroscience more details view paper
  • Downloaded 665 times
  • Download rankings, all-time:
    • Site-wide: 14,274 out of 67,044
    • In neuroscience: 2,365 out of 12,017
  • Year to date:
    • Site-wide: 61,013 out of 67,044
  • Since beginning of last month:
    • Site-wide: 36,990 out of 67,044

Cushing's Syndrome mutant PKAL205R exhibits altered substrate specificity

biochemistry more details view paper
  • Downloaded 616 times
  • Download rankings, all-time:
    • Site-wide: 15,938 out of 67,044
    • In biochemistry: 336 out of 1,974
  • Year to date:
    • Site-wide: 49,892 out of 67,044
  • Since beginning of last month:
    • Site-wide: 51,093 out of 67,044

Toward D-Peptide Biosynthesis: Elongation Factor P Enables Ribosomal Incorporation Of Consecutive D-Amino Acids

biochemistry more details view paper
  • Downloaded 609 times
  • Download rankings, all-time:
    • Site-wide: 16,176 out of 67,044
    • In biochemistry: 342 out of 1,974
  • Year to date:
    • Site-wide: 43,138 out of 67,044
  • Since beginning of last month:
    • Site-wide: 46,335 out of 67,044

Millstone: Software for Multiplex Microbial Genome Analysis and Engineering

synthetic biology more details view paper
  • Downloaded 568 times
  • Download rankings, all-time:
    • Site-wide: 17,812 out of 67,044
    • In synthetic biology: 295 out of 638
  • Year to date:
    • Site-wide: 49,954 out of 67,044
  • Since beginning of last month:
    • Site-wide: 49,073 out of 67,044

Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli

genomics more details view paper
  • Downloaded 462 times
  • Download rankings, all-time:
    • Site-wide: 23,066 out of 67,044
    • In genomics: 2,546 out of 4,558
  • Year to date:
    • Site-wide: 57,623 out of 67,044
  • Since beginning of last month:
    • Site-wide: 32,926 out of 67,044

Simulating serial-target antibacterial drug synergies using flux balance analysis

systems biology more details view paper
  • Downloaded 426 times
  • Download rankings, all-time:
    • Site-wide: 25,354 out of 67,044
    • In systems biology: 762 out of 1,863
  • Year to date:
    • Site-wide: 64,823 out of 67,044
  • Since beginning of last month:
    • Site-wide: 62,744 out of 67,044

Citizen-Centered, Auditable, and Privacy-Preserving Population Genomics

genomics more details view paper
  • Downloaded 377 times
  • Download rankings, all-time:
    • Site-wide: 28,871 out of 67,044
    • In genomics: 2,935 out of 4,558
  • Year to date:
    • Site-wide: 10,133 out of 67,044
  • Since beginning of last month:
    • Site-wide: 3,749 out of 67,044

Physiological Assembly Of Functionally Active 30S Ribosomal Subunits From In Vitro Synthesized Parts

biochemistry more details view paper
  • Downloaded 346 times
  • Download rankings, all-time:
    • Site-wide: 31,552 out of 67,044
    • In biochemistry: 802 out of 1,974
  • Year to date:
    • Site-wide: 56,778 out of 67,044
  • Since beginning of last month:
    • Site-wide: 46,611 out of 67,044

Towards Practical and Robust DNA-based Data Archiving by Codec System Named 'Yin-Yang'

synthetic biology more details view paper
  • Downloaded 193 times
  • Download rankings, all-time:
    • Site-wide: 48,990 out of 67,044
    • In synthetic biology: 582 out of 638
  • Year to date:
    • Site-wide: 26,046 out of 67,044
  • Since beginning of last month:
    • Site-wide: 841 out of 67,044

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