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Author: Richard M. Murray

Rankings

  • All-time downloads: 53,511 (rank: 2,335 )
  • Categories:
    • bioengineering: 3,318 (rank: 388 )
    • evolutionary biology: 2,620 (rank: 1,504 (tie) )
    • synthetic biology: 41,809 (rank: 3 )
    • systems biology: 5,764 (rank: 518 )

Downloads per author, site-wide

Preprints

Resource usage and gene circuit performance characterization in a cell-free ?breadboard?

synthetic biology more details view paper
  • Downloaded 4,027 times
  • Download rankings, all-time:
    • Site-wide: 2,352
    • In synthetic biology: 21
  • Year to date:
    • Site-wide: 5,779
  • Since beginning of last month:
    • Site-wide: 34,229

Development of prokaryotic cell-free systems for synthetic biology

synthetic biology more details view paper
  • Downloaded 2,951 times
  • Download rankings, all-time:
    • Site-wide: 3,698
    • In synthetic biology: 36
  • Year to date:
    • Site-wide: 24,724
  • Since beginning of last month:
    • Site-wide: 62,003

A Scalable Formulation for Engineering Combination Therapies for Evolutionary Dynamics of Disease

evolutionary biology more details view paper
  • Downloaded 1,822 times
  • Download rankings, all-time:
    • Site-wide: 7,487
    • In evolutionary biology: 231
  • Year to date:
    • Site-wide: 100,490
  • Since beginning of last month:
    • Site-wide: 79,626

An analytical approach to bistable biological circuit discrimination using real algebraic geometry

systems biology more details view paper
  • Downloaded 1,762 times
  • Download rankings, all-time:
    • Site-wide: 7,875
    • In systems biology: 144
  • Year to date:
    • Site-wide: 50,658
  • Since beginning of last month:
    • Site-wide: 38,949

Design Space Exploration of the Violacein Pathway in Escherichia coli Based Transcription Translation Cell-Free System (TX-TL)

synthetic biology more details view paper
  • Downloaded 1,597 times
  • Download rankings, all-time:
    • Site-wide: 9,191
    • In synthetic biology: 97
  • Year to date:
    • Site-wide: 25,408
  • Since beginning of last month:
    • Site-wide: 32,992

Control of bacterial population density with population feedback and molecular sequestration

synthetic biology more details view paper
  • Downloaded 1,443 times
  • Download rankings, all-time:
    • Site-wide: 10,666
    • In synthetic biology: 115
  • Year to date:
    • Site-wide: 44,312
  • Since beginning of last month:
    • Site-wide: 32,804

Prototyping 1,4-butanediol (BDO) biosynthesis pathway in a cell-free transcription-translation (TX-TL) system

synthetic biology more details view paper
  • Downloaded 1,417 times
  • Download rankings, all-time:
    • Site-wide: 10,964
    • In synthetic biology: 120
  • Year to date:
    • Site-wide: 57,479
  • Since beginning of last month:
    • Site-wide: 48,146

Proof of concept continuous event logging in living cells

synthetic biology more details view paper
  • Downloaded 1,392 times
  • Download rankings, all-time:
    • Site-wide: 11,274
    • In synthetic biology: 128
  • Year to date:
    • Site-wide: 47,280
  • Since beginning of last month:
    • Site-wide: 35,008

Design and implementation of a synthetic biomolecular concentration tracker

synthetic biology more details view paper
  • Downloaded 1,337 times
  • Download rankings, all-time:
    • Site-wide: 11,985
    • In synthetic biology: 143
  • Year to date:
    • Site-wide: 16,984
  • Since beginning of last month:
    • Site-wide: 70,255

Hard Limits And Performance Tradeoffs In A Class Of Sequestration Feedback Systems

systems biology more details view paper
  • Downloaded 1,332 times
  • Download rankings, all-time:
    • Site-wide: 12,045
    • In systems biology: 244
  • Year to date:
    • Site-wide: 43,350
  • Since beginning of last month:
    • Site-wide: 61,501

Synthetic logic circuits using RNA aptamer against T7 RNA polymerase

synthetic biology more details view paper
  • Downloaded 1,310 times
  • Download rankings, all-time:
    • Site-wide: 12,353
    • In synthetic biology: 149
  • Year to date:
    • Site-wide: 82,137
  • Since beginning of last month:
    • Site-wide: 67,020

Fast and flexible simulation and parameter estimation for synthetic biology using bioscrape

synthetic biology more details view paper
  • Downloaded 1,227 times
  • Download rankings, all-time:
    • Site-wide: 13,617
    • In synthetic biology: 167
  • Year to date:
    • Site-wide: 10,353
  • Since beginning of last month:
    • Site-wide: 28,595

The Effect of Compositional Context on Synthetic Gene Networks

synthetic biology more details view paper
  • Downloaded 1,203 times
  • Download rankings, all-time:
    • Site-wide: 14,044
    • In synthetic biology: 179
  • Year to date:
    • Site-wide: 100,555
  • Since beginning of last month:
    • Site-wide: 89,120

A cell-free framework for biological systems engineering

synthetic biology more details view paper
  • Downloaded 1,153 times
  • Download rankings, all-time:
    • Site-wide: 14,943
    • In synthetic biology: 189
  • Year to date:
    • Site-wide: 86,654
  • Since beginning of last month:
    • Site-wide: 84,658

Synthetic mammalian signaling circuits for robust cell population control

synthetic biology more details view paper
  • Downloaded 1,121 times
  • Download rankings, all-time:
    • Site-wide: 15,583
    • In synthetic biology: 200
  • Year to date:
    • Site-wide: 4,831
  • Since beginning of last month:
    • Site-wide: 2,039

Design of a Toolbox of RNA Thermometers

synthetic biology more details view paper
  • Downloaded 1,032 times
  • Download rankings, all-time:
    • Site-wide: 17,675
    • In synthetic biology: 227
  • Year to date:
    • Site-wide: 91,300
  • Since beginning of last month:
    • Site-wide: 86,951

A population-based temporal logic gate for timing and recording chemical events

synthetic biology more details view paper
  • Downloaded 968 times
  • Download rankings, all-time:
    • Site-wide: 19,437
    • In synthetic biology: 252
  • Year to date:
    • Site-wide: 96,409
  • Since beginning of last month:
    • Site-wide: 56,019

Characterizing and Prototyping Genetic Networks with Cell-Free Transcription-Translation Reactions

synthetic biology more details view paper
  • Downloaded 908 times
  • Download rankings, all-time:
    • Site-wide: 21,292
    • In synthetic biology: 280
  • Year to date:
    • Site-wide: 45,623
  • Since beginning of last month:
    • Site-wide: 105,706

Engineering Transcriptional Regulator Effector Specificity using Computational Design and In Vitro Rapid Prototyping: Developing a Vanillin Sensor

synthetic biology more details view paper
  • Downloaded 898 times
  • Download rankings, all-time:
    • Site-wide: 21,672
    • In synthetic biology: 284
  • Year to date:
    • Site-wide: 92,421
  • Since beginning of last month:
    • Site-wide: 71,352

Modeling Dynamic Transcriptional Circuits with CRISPRi

synthetic biology more details view paper
  • Downloaded 849 times
  • Download rankings, all-time:
    • Site-wide: 23,494
    • In synthetic biology: 305
  • Year to date:
    • Site-wide: 56,275
  • Since beginning of last month:
    • Site-wide: 81,109

System-level studies of a cell-free transcription-translation platform for metabolic engineering

bioengineering more details view paper
  • Downloaded 833 times
  • Download rankings, all-time:
    • Site-wide: 24,145
    • In bioengineering: 401
  • Year to date:
    • Site-wide: 94,406
  • Since beginning of last month:
    • Site-wide: 54,871

Population diversification in a yeast metabolic program promotes anticipation of environmental shifts

systems biology more details view paper
  • Downloaded 826 times
  • Download rankings, all-time:
    • Site-wide: 24,420
    • In systems biology: 534
  • Year to date:
    • Site-wide: 99,731
  • Since beginning of last month:
    • Site-wide: 121,617

Control of density and composition in an engineered two-member bacterial community

synthetic biology more details view paper
  • Downloaded 785 times
  • Download rankings, all-time:
    • Site-wide: 26,192
    • In synthetic biology: 345
  • Year to date:
    • Site-wide: 56,419
  • Since beginning of last month:
    • Site-wide: 29,982

Designing Robustness to Temperature in a Feedforward Loop Circuit

synthetic biology more details view paper
  • Downloaded 777 times
  • Download rankings, all-time:
    • Site-wide: 26,580
    • In synthetic biology: 348
  • Year to date:
    • Site-wide: 44,255
  • Since beginning of last month:
    • Site-wide: 77,875

Expressing Biologically Active Membrane Proteins in a Cell-Free Transcription-Translation Platform

bioengineering more details view paper
  • Downloaded 762 times
  • Download rankings, all-time:
    • Site-wide: 27,311
    • In bioengineering: 464
  • Year to date:
    • Site-wide: 70,275
  • Since beginning of last month:
    • Site-wide: 83,758

Length and time scales of cell-cell signaling circuits in agar

synthetic biology more details view paper
  • Downloaded 753 times
  • Download rankings, all-time:
    • Site-wide: 27,813
    • In synthetic biology: 364
  • Year to date:
    • Site-wide: 54,062
  • Since beginning of last month:
    • Site-wide: 105,780

Role of interaction network topology in controlling microbial population in consortia

synthetic biology more details view paper
  • Downloaded 740 times
  • Download rankings, all-time:
    • Site-wide: 28,494
    • In synthetic biology: 372
  • Year to date:
    • Site-wide: 91,562
  • Since beginning of last month:
    • Site-wide: 76,726

Negative autoregulation matches production and demand in synthetic transcriptional networks

synthetic biology more details view paper
  • Downloaded 711 times
  • Download rankings, all-time:
    • Site-wide: 30,083
    • In synthetic biology: 395
  • Year to date:
    • Site-wide: 110,050
  • Since beginning of last month:
    • Site-wide: 67,378

Cell-free and in vivo characterization of Lux, Las, and Rpa quorum activation systems in E. coli

synthetic biology more details view paper
  • Downloaded 687 times
  • Download rankings, all-time:
    • Site-wide: 31,449
    • In synthetic biology: 415
  • Year to date:
    • Site-wide: 108,743
  • Since beginning of last month:
    • Site-wide: 106,073

Population regulation in microbial consortia using dual feedback control

synthetic biology more details view paper
  • Downloaded 686 times
  • Download rankings, all-time:
    • Site-wide: 31,553
    • In synthetic biology: 417
  • Year to date:
    • Site-wide: 87,316
  • Since beginning of last month:
    • Site-wide: 103,429

Single day construction of multi-gene circuits with 3G assembly

bioengineering more details view paper
  • Downloaded 671 times
  • Download rankings, all-time:
    • Site-wide: 32,534
    • In bioengineering: 571
  • Year to date:
    • Site-wide: 62,550
  • Since beginning of last month:
    • Site-wide: 92,075

Modeling predicts that CRISPR-based activators, unlike CRISPR-based repressors, scale well with increasing gRNA competition and dCas9 bottlenecking

synthetic biology more details view paper
  • Downloaded 644 times
  • Download rankings, all-time:
    • Site-wide: 34,323
    • In synthetic biology: 447
  • Year to date:
    • Site-wide: 85,502
  • Since beginning of last month:
    • Site-wide: 82,894

Finding analytic stationary solutions to the chemical master equation by gluing state spaces at one or two states recursively

systems biology more details view paper
  • Downloaded 629 times
  • Download rankings, all-time:
    • Site-wide: 35,417
    • In systems biology: 834
  • Year to date:
    • Site-wide: 48,821
  • Since beginning of last month:
    • Site-wide: 73,145

Long-distance communication in synthetic bacterial consortia through active signal propagation

synthetic biology more details view paper
  • Downloaded 622 times
  • Download rankings, all-time:
    • Site-wide: 35,945
    • In synthetic biology: 464
  • Year to date:
    • Site-wide: 13,362
  • Since beginning of last month:
    • Site-wide: 52,979

Tunable integrase-mediated differentiation facilitates improved output of burdensome functions in E. coli

synthetic biology more details view paper
  • Downloaded 590 times
  • Download rankings, all-time:
    • Site-wide: 38,379
    • In synthetic biology: 490
  • Year to date:
    • Site-wide: 35,065
  • Since beginning of last month:
    • Site-wide: 33,824

Repressing Integrase attachment site operation with CRISPR-Cas9 in E. coli

synthetic biology more details view paper
  • Downloaded 585 times
  • Download rankings, all-time:
    • Site-wide: 38,859
    • In synthetic biology: 495
  • Year to date:
    • Site-wide: 117,825
  • Since beginning of last month:
    • Site-wide: 120,030

Design Guidelines For Sequestration Feedback Networks

synthetic biology more details view paper
  • Downloaded 571 times
  • Download rankings, all-time:
    • Site-wide: 40,061
    • In synthetic biology: 510
  • Year to date:
    • Site-wide: 117,492
  • Since beginning of last month:
    • Site-wide: 83,196

Synthesizing Combination Therapies for Evolutionary Dynamics of Disease for Nonlinear Pharmacodynamics

evolutionary biology more details view paper
  • Downloaded 562 times
  • Download rankings, all-time:
    • Site-wide: 40,831
    • In evolutionary biology: 2,226
  • Year to date:
    • Site-wide: 72,890
  • Since beginning of last month:
    • Site-wide: 86,691

Context Dependence of Biological Circuits

synthetic biology more details view paper
  • Downloaded 559 times
  • Download rankings, all-time:
    • Site-wide: 41,139
    • In synthetic biology: 518
  • Year to date:
    • Site-wide: 53,342
  • Since beginning of last month:
    • Site-wide: 53,228

Prototyping And Implementation Of A Novel Feedforward Loop In A Cell-Free Transcription-Translation System And Cells

bioengineering more details view paper
  • Downloaded 553 times
  • Download rankings, all-time:
    • Site-wide: 41,670
    • In bioengineering: 733
  • Year to date:
    • Site-wide: 64,543
  • Since beginning of last month:
    • Site-wide: 61,705

Rapidly characterizing the fast dynamics of RNA genetic circuitry with cell-free transcription-translation (TX-TL) systems

synthetic biology more details view paper
  • Downloaded 548 times
  • Download rankings, all-time:
    • Site-wide: 42,102
    • In synthetic biology: 527
  • Year to date:
    • Site-wide: 118,944
  • Since beginning of last month:
    • Site-wide: 120,618

Engineering pulsatile communication in bacterial consortia

synthetic biology more details view paper
  • Downloaded 530 times
  • Download rankings, all-time:
    • Site-wide: 43,933
    • In synthetic biology: 552
  • Year to date:
    • Site-wide: 115,366
  • Since beginning of last month:
    • Site-wide: 118,913

Protein degradation in a TX-TL cell-free expression system using ClpXP protease

synthetic biology more details view paper
  • Downloaded 529 times
  • Download rankings, all-time:
    • Site-wide: 44,003
    • In synthetic biology: 553
  • Year to date:
    • Site-wide: 73,823
  • Since beginning of last month:
    • Site-wide: 108,458

Implementation and System Identification of a Phosphorylation-Based Insulator in a Cell-Free Transcription-Translation System

bioengineering more details view paper
  • Downloaded 499 times
  • Download rankings, all-time:
    • Site-wide: 47,103
    • In bioengineering: 864
  • Year to date:
    • Site-wide: 116,309
  • Since beginning of last month:
    • Site-wide: 115,048

An automated model reduction tool to guide the design and analysis of synthetic biological circuits

synthetic biology more details view paper
  • Downloaded 499 times
  • Download rankings, all-time:
    • Site-wide: 47,081
    • In synthetic biology: 586
  • Year to date:
    • Site-wide: 88,098
  • Since beginning of last month:
    • Site-wide: 53,472

The effects of time-varying temperature on delays in genetic networks

systems biology more details view paper
  • Downloaded 498 times
  • Download rankings, all-time:
    • Site-wide: 47,255
    • In systems biology: 1,132
  • Year to date:
    • Site-wide: 78,658
  • Since beginning of last month:
    • Site-wide: 110,471

Cooperation Enhances Robustness of Coexistence in Spatially Structured Consortia

synthetic biology more details view paper
  • Downloaded 490 times
  • Download rankings, all-time:
    • Site-wide: 48,138
    • In synthetic biology: 590
  • Year to date:
    • Site-wide: 33,860
  • Since beginning of last month:
    • Site-wide: 118,573

Bacterial Controller Aided Wound Healing: A Case Study in Dynamical Population Controller Design

synthetic biology more details view paper
  • Downloaded 450 times
  • Download rankings, all-time:
    • Site-wide: 52,927
    • In synthetic biology: 639
  • Year to date:
    • Site-wide: 118,693
  • Since beginning of last month:
    • Site-wide: 85,942

A geometric and structural approach to the analysis and design of biological circuit dynamics: a theory tailored for synthetic biology

synthetic biology more details view paper
  • Downloaded 449 times
  • Download rankings, all-time:
    • Site-wide: 53,091
    • In synthetic biology: 641
  • Year to date:
    • Site-wide: 99,544
  • Since beginning of last month:
    • Site-wide: 68,395

Negative Feedback Facilitates Temperature Robustness in Biomolecular Circuit Dynamics

systems biology more details view paper
  • Downloaded 442 times
  • Download rankings, all-time:
    • Site-wide: 54,009
    • In systems biology: 1,328
  • Year to date:
    • Site-wide: 117,854
  • Since beginning of last month:
    • Site-wide: 102,919

Design of a genetic layered feedback controller in synthetic biological circuitry

synthetic biology more details view paper
  • Downloaded 441 times
  • Download rankings, all-time:
    • Site-wide: 54,045
    • In synthetic biology: 654
  • Year to date:
    • Site-wide: 90,936
  • Since beginning of last month:
    • Site-wide: 97,192

The role of single occupancy effects on integrase dynamics in a cell-free system

synthetic biology more details view paper
  • Downloaded 433 times
  • Download rankings, all-time:
    • Site-wide: 55,208
    • In synthetic biology: 660
  • Year to date:
    • Site-wide: 116,818
  • Since beginning of last month:
    • Site-wide: 82,270

A Method for Cost-Effective and Rapid Characterization of Engineered T7-based Transcription Factors by Cell-Free Protein Synthesis Reveals Insights into the Regulation of T7 RNA Polymerase-Driven Expression

synthetic biology more details view paper
  • Downloaded 430 times
  • Download rankings, all-time:
    • Site-wide: 55,617
    • In synthetic biology: 667
  • Year to date:
    • Site-wide: 75,033
  • Since beginning of last month:
    • Site-wide: 70,451

Model Reduction Tools For Phenomenological Modeling of Input-Controlled Biological Circuits

synthetic biology more details view paper
  • Downloaded 417 times
  • Download rankings, all-time:
    • Site-wide: 57,402
    • In synthetic biology: 684
  • Year to date:
    • Site-wide: 68,693
  • Since beginning of last month:
    • Site-wide: 36,414

Addressable, "Packet-Based" Intercellular Communication through Plasmid Conjugation

synthetic biology more details view paper
  • Downloaded 412 times
  • Download rankings, all-time:
    • Site-wide: 58,113
    • In synthetic biology: 688
  • Year to date:
    • Site-wide: 121,058
  • Since beginning of last month:
    • Site-wide: 108,765

A MATLAB Toolbox for Modeling Genetic Circuits in Cell-Free Systems

synthetic biology more details view paper
  • Downloaded 380 times
  • Download rankings, all-time:
    • Site-wide: 62,856
    • In synthetic biology: 727
  • Year to date:
    • Site-wide: 59,985
  • Since beginning of last month:
    • Site-wide: 29,585

BioCRNpyler: Compiling Chemical Reaction Networks from Biomolecular Parts in Diverse Contexts

synthetic biology more details view paper
  • Downloaded 334 times
  • Download rankings, all-time:
    • Site-wide: 70,490
    • In synthetic biology: 779
  • Year to date:
    • Site-wide: 17,442
  • Since beginning of last month:
    • Site-wide: 21,513

Layered Feedback Control Improves Robust Functionality across Heterogeneous Cell Populations

synthetic biology more details view paper
  • Downloaded 329 times
  • Download rankings, all-time:
    • Site-wide: 71,447
    • In synthetic biology: 789
  • Year to date:
    • Site-wide: 80,555
  • Since beginning of last month:
    • Site-wide: 27,807

A Bayesian approach to inferring chemical signal timing and amplitude in a temporal logic gate using the cell population distributional response

synthetic biology more details view paper
  • Downloaded 313 times
  • Download rankings, all-time:
    • Site-wide: 74,302
    • In synthetic biology: 803
  • Year to date:
    • Site-wide: 106,906
  • Since beginning of last month:
    • Site-wide: 106,884

Engineering Logical Inflammation Sensing Circuit for Modulating Gut Conditions

synthetic biology more details view paper
  • Downloaded 306 times
  • Download rankings, all-time:
    • Site-wide: 75,572
    • In synthetic biology: 815
  • Year to date:
    • Site-wide: 14,145
  • Since beginning of last month:
    • Site-wide: 9,309

Theoretical Design of Paradoxical Signaling-Based Synthetic Population Control Circuit in E. coli

systems biology more details view paper
  • Downloaded 275 times
  • Download rankings, all-time:
    • Site-wide: 81,701
    • In systems biology: 1,985
  • Year to date:
    • Site-wide: 64,941
  • Since beginning of last month:
    • Site-wide: 47,121

Assessment of Robustness to Temperature in a Negative Feedback Loop and a Feedforward Loop

synthetic biology more details view paper
  • Downloaded 268 times
  • Download rankings, all-time:
    • Site-wide: 83,002
    • In synthetic biology: 857
  • Year to date:
    • Site-wide: 120,800
  • Since beginning of last month:
    • Site-wide: 91,363

Quantitative characterization of random partitioning in the evolution of plasmid-encoded traits

evolutionary biology more details view paper
  • Downloaded 236 times
  • Download rankings, all-time:
    • Site-wide: 89,733
    • In evolutionary biology: 4,930
  • Year to date:
    • Site-wide: 120,456
  • Since beginning of last month:
    • Site-wide: 118,793

Bistable State Switch Enables Ultrasensitive Feedback Control in Heterogeneous Microbial Populations

synthetic biology more details view paper
  • Downloaded 206 times
  • Download rankings, all-time:
    • Site-wide: 96,133
    • In synthetic biology: 914
  • Year to date:
    • Site-wide: 35,596
  • Since beginning of last month:
    • Site-wide: 10,294

Construction of an inducible amyloid expression circuit in Bacillus megaterium: A case study with CsgA and TasA

synthetic biology more details view paper
  • Downloaded 200 times
  • Download rankings, all-time:
    • Site-wide: 97,474
    • In synthetic biology: 922
  • Year to date:
    • Site-wide: 38,636
  • Since beginning of last month:
    • Site-wide: 83,260

A two-state ribosome and protein model can robustly capture the chemical reaction dynamics of gene expression

synthetic biology more details view paper
  • Downloaded 163 times
  • Download rankings, all-time:
    • Site-wide: 104,773
    • In synthetic biology: 944
  • Year to date:
    • Site-wide: 35,985
  • Since beginning of last month:
    • Site-wide: 7,712

Analysis of Circuits for Dosage Control in Microbial Populations

synthetic biology more details view paper
  • Downloaded 139 times
  • Download rankings, all-time:
    • Site-wide: 109,357
    • In synthetic biology: 964
  • Year to date:
    • Site-wide: 8,398
  • Since beginning of last month:
    • Site-wide: 4,974

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