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Author: Nir Hacohen

  • ORCiD: http://orcid.org/0000-0002-2349-2656
  • Most recently observed institution: Broad Institute of MIT and Harvard, Cambridge, MA, USA; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.

Rankings

  • All-time downloads: 77,961 (rank: 1,780 (tie) )
  • Categories:
    • bioengineering: 3,071 (rank: 556 )
    • bioinformatics: 2,445 (rank: 5,582 (tie) )
    • cancer biology: 5,258 (rank: 517 (tie) )
    • cardiovascular medicine: 187 (rank: 2,254 (tie) )
    • cell biology: 12,603 (rank: 197 (tie) )
    • genetics: 2,546 (rank: 7,172 (tie) )
    • genomics: 24,693 (rank: 371 )
    • immunology: 19,586 (rank: 417 )
    • infectious diseases: 3,385 (rank: 9,731 )
    • physiology: 312 (rank: 5,370 (tie) )
    • rheumatology: 414 (rank: 551 (tie) )
    • systems biology: 3,461 (rank: 1,004 (tie) )

Downloads per author, site-wide

Preprints

Differentiation of exhausted CD8 T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory

immunology more details view paper

No download data for this paper yet.

Systematic comparative analysis of single cell RNA-sequencing methods

genomics more details view paper
  • Downloaded 14,069 times
  • Download rankings, all-time:
    • Site-wide: 488
    • In genomics: 29
  • Year to date:
    • Site-wide: 1,651
  • Since beginning of last month:
    • Site-wide: 2,198

The Human Cell Atlas

cell biology more details view paper
  • Downloaded 12,603 times
  • Download rankings, all-time:
    • Site-wide: 581
    • In cell biology: 4
  • Year to date:
    • Site-wide: 21,175
  • Since beginning of last month:
    • Site-wide: 17,568

A protocol for single-cell transcriptomics from cryopreserved renal tissue and urine for the Accelerating Medicine Partnership (AMP) RA/SLE network

immunology more details view paper
  • Downloaded 5,952 times
  • Download rankings, all-time:
    • Site-wide: 1,551
    • In immunology: 36
  • Year to date:
    • Site-wide: 3,652
  • Since beginning of last month:
    • Site-wide: 3,885

Defining Inflammatory Cell States in Rheumatoid Arthritis Joint Synovial Tissues by Integrating Single-cell Transcriptomics and Mass Cytometry

immunology more details view paper
  • Downloaded 4,341 times
  • Download rankings, all-time:
    • Site-wide: 2,412
    • In immunology: 69
  • Year to date:
    • Site-wide: 25,451
  • Since beginning of last month:
    • Site-wide: 18,857

Thousands of novel unannotated proteins expand the MHC I immunopeptidome in cancer

cancer biology more details view paper
  • Downloaded 3,754 times
  • Download rankings, all-time:
    • Site-wide: 2,982
    • In cancer biology: 43
  • Year to date:
    • Site-wide: 1,968
  • Since beginning of last month:
    • Site-wide: 1,656

Plasma proteomics reveals tissue-specific cell death and mediators of cell-cell interactions in severe COVID-19 patients

systems biology more details view paper
  • Downloaded 3,461 times
  • Download rankings, all-time:
    • Site-wide: 3,351
    • In systems biology: 50
  • Year to date:
    • Site-wide: 584
  • Since beginning of last month:
    • Site-wide: 538

Temporal and Spatial Heterogeneity of Host Response to SARS-CoV-2 Pulmonary Infection

infectious diseases more details view paper
  • Downloaded 2,889 times
  • Download rankings, all-time:
    • Site-wide: 4,312
    • In infectious diseases: 742
  • Year to date:
    • Site-wide: 3,480
  • Since beginning of last month:
    • Site-wide: 3,340

Genome-wide maps of enhancer regulation connect risk variants to disease genes

genetics more details view paper
  • Downloaded 2,546 times
  • Download rankings, all-time:
    • Site-wide: 5,185
    • In genetics: 237
  • Year to date:
    • Site-wide: 2,701
  • Since beginning of last month:
    • Site-wide: 2,771

SARS-CoV-2 infected cells present HLA-I peptides from canonical and out-of-frame ORFs

immunology more details view paper
  • Downloaded 2,489 times
  • Download rankings, all-time:
    • Site-wide: 5,385
    • In immunology: 152
  • Year to date:
    • Site-wide: 2,971
  • Since beginning of last month:
    • Site-wide: 5,895

A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2

genomics more details view paper
  • Downloaded 2,440 times
  • Download rankings, all-time:
    • Site-wide: 5,557
    • In genomics: 638
  • Year to date:
    • Site-wide: 357
  • Since beginning of last month:
    • Site-wide: 172

Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease.

genomics more details view paper
  • Downloaded 2,177 times
  • Download rankings, all-time:
    • Site-wide: 6,547
    • In genomics: 732
  • Year to date:
    • Site-wide: 107,560
  • Since beginning of last month:
    • Site-wide: 98,120

The immune cell landscape in kidneys of lupus nephritis patients

immunology more details view paper
  • Downloaded 2,141 times
  • Download rankings, all-time:
    • Site-wide: 6,717
    • In immunology: 193
  • Year to date:
    • Site-wide: 33,609
  • Since beginning of last month:
    • Site-wide: 31,706

Landscape of X chromosome inactivation across human tissues

genomics more details view paper
  • Downloaded 2,054 times
  • Download rankings, all-time:
    • Site-wide: 7,123
    • In genomics: 789
  • Year to date:
    • Site-wide: 73,603
  • Since beginning of last month:
    • Site-wide: 53,727

Single Cell Transcriptomics And Flow Cytometry Reveal Disease-Associated Fibroblast Subsets In Rheumatoid Arthritis

immunology more details view paper
  • Downloaded 1,809 times
  • Download rankings, all-time:
    • Site-wide: 8,634
    • In immunology: 251
  • Year to date:
    • Site-wide: 61,657
  • Since beginning of last month:
    • Site-wide: 60,480

Cumulus: a cloud-based data analysis framework for large-scale single-cell and single-nucleus RNA-seq

bioinformatics more details view paper
  • Downloaded 1,793 times
  • Download rankings, all-time:
    • Site-wide: 8,748
    • In bioinformatics: 1,062
  • Year to date:
    • Site-wide: 16,434
  • Since beginning of last month:
    • Site-wide: 14,521

GeNets: A unified web platform for network-based analyses of genomic data

genomics more details view paper
  • Downloaded 1,684 times
  • Download rankings, all-time:
    • Site-wide: 9,625
    • In genomics: 1,058
  • Year to date:
    • Site-wide: 46,366
  • Since beginning of last month:
    • Site-wide: 97,758

Multicellular immune hubs and their organization in MMRd and MMRp colorectal cancer

cancer biology more details view paper
  • Downloaded 1,504 times
  • Download rankings, all-time:
    • Site-wide: 11,307
    • In cancer biology: 226
  • Year to date:
    • Site-wide: 622
  • Since beginning of last month:
    • Site-wide: 767

An eQTL landscape of kidney tissue in human nephrotic syndrome

genomics more details view paper
  • Downloaded 1,302 times
  • Download rankings, all-time:
    • Site-wide: 14,083
    • In genomics: 1,493
  • Year to date:
    • Site-wide: 73,382
  • Since beginning of last month:
    • Site-wide: 103,353

Induction of a regulatory myeloid program in bacterial sepsis and severe COVID-19

immunology more details view paper
  • Downloaded 1,257 times
  • Download rankings, all-time:
    • Site-wide: 14,867
    • In immunology: 431
  • Year to date:
    • Site-wide: 8,102
  • Since beginning of last month:
    • Site-wide: 8,703

Targeting individual cells by barcode in pooled sequence libraries

bioengineering more details view paper
  • Downloaded 1,194 times
  • Download rankings, all-time:
    • Site-wide: 16,060
    • In bioengineering: 271
  • Year to date:
    • Site-wide: 127,623
  • Since beginning of last month:
    • Site-wide: 119,873

High dimensional analyses of cells dissociated from cryopreserved synovial tissue

immunology more details view paper
  • Downloaded 1,121 times
  • Download rankings, all-time:
    • Site-wide: 17,656
    • In immunology: 510
  • Year to date:
    • Site-wide: 68,417
  • Since beginning of last month:
    • Site-wide: 74,881

A cell-free antibody engineering platform rapidly generates SARS-CoV-2 neutralizing antibodies

bioengineering more details view paper
  • Downloaded 1,087 times
  • Download rankings, all-time:
    • Site-wide: 18,449
    • In bioengineering: 313
  • Year to date:
    • Site-wide: 7,112
  • Since beginning of last month:
    • Site-wide: 6,462

Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of ERAP2 transcripts under balancing selection

genomics more details view paper
  • Downloaded 967 times
  • Download rankings, all-time:
    • Site-wide: 21,854
    • In genomics: 2,157
  • Year to date:
    • Site-wide: 87,001
  • Since beginning of last month:
    • Site-wide: 103,285

Multiplexed enrichment and genomic profiling of peripheral immune cell subsets on a microfluidic chip

bioengineering more details view paper
  • Downloaded 790 times
  • Download rankings, all-time:
    • Site-wide: 29,132
    • In bioengineering: 507
  • Year to date:
    • Site-wide: 125,864
  • Since beginning of last month:
    • Site-wide: 119,794

MAUDE: Inferring expression changes in sorting-based CRISPR screens

bioinformatics more details view paper
  • Downloaded 652 times
  • Download rankings, all-time:
    • Site-wide: 37,869
    • In bioinformatics: 4,162
  • Year to date:
    • Site-wide: 124,024
  • Since beginning of last month:
    • Site-wide: 121,770

SARS-CoV-2 Viremia is Associated with Distinct Proteomic Pathways and Predicts COVID-19 Outcomes

infectious diseases more details view paper
  • Downloaded 496 times
  • Download rankings, all-time:
    • Site-wide: 52,912
    • In infectious diseases: 2,709
  • Year to date:
    • Site-wide: 2,788
  • Since beginning of last month:
    • Site-wide: 1,551

Integration of urine proteomics and renal single-cell genomics identifies an interferon-gamma response gradient in lupus nephritis.

rheumatology more details view paper
  • Downloaded 414 times
  • Download rankings, all-time:
    • Site-wide: 64,294
    • In rheumatology: 42
  • Year to date:
    • Site-wide: 56,903
  • Since beginning of last month:
    • Site-wide: 39,356

SLAMF6 deficiency augments tumor killing and skews towards an effector phenotype revealing it as a new T cell checkpoint

physiology more details view paper
  • Downloaded 312 times
  • Download rankings, all-time:
    • Site-wide: 82,319
    • In physiology: 678
  • Year to date:
    • Site-wide: 89,536
  • Since beginning of last month:
    • Site-wide: 85,227

Alternative splicing of SLAMF6 in human T cells creates a co-stimulatory isoform that counteracts the inhibitory effect of the full-length receptor

immunology more details view paper
  • Downloaded 244 times
  • Download rankings, all-time:
    • Site-wide: 96,784
    • In immunology: 2,733
  • Year to date:
    • Site-wide: 32,551
  • Since beginning of last month:
    • Site-wide: 29,389

An efficient lentiviral CRISPRi approach to silence genes in primary human monocytes

immunology more details view paper
  • Downloaded 232 times
  • Download rankings, all-time:
    • Site-wide: 99,436
    • In immunology: 2,814
  • Year to date:
    • Site-wide: 18,270
  • Since beginning of last month:
    • Site-wide: 38,809

Application of a 27-protein candidate cardiovascular surrogate endpoint to track risk ascendancy and resolution in COVID-19.

cardiovascular medicine more details view paper
  • Downloaded 187 times
  • Download rankings, all-time:
    • Site-wide: 109,368
    • In cardiovascular medicine: 235
  • Year to date:
    • Site-wide: 11,149
  • Since beginning of last month:
    • Site-wide: 9,666

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