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Author: David J. Porteous

  • ORCiD: http://orcid.org/0000-0003-1249-6106
  • Most recently observed institution: Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Western General Hospital

Rankings

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    • genetics: 36,216 (rank: 106 out of 35,526)
    • genomics: 5,763 (rank: 2,959 out of 40,907)
    • neuroscience: 162 (rank: 57,440 (tie) out of 64,424)

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Preprints

Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

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Genomic analysis of family data reveals additional genetic effects on intelligence and personality

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Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

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Genetic analysis identifies molecular systems and biological pathways associated with household income

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Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

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Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112,117).

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GWAS on family history of Alzheimer's disease

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Genetic Prediction of Male Pattern Baldness

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Genetic stratification of depression in UK Biobank suggests a subgroup linked to age of natural menopause

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Epigenetic prediction of complex traits and death

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Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

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Do Regional Brain Volumes and Major Depressive Disorder Share Genetic Architecture: a study in Generation Scotland (n=19,762), UK Biobank (n=24,048) and the English Longitudinal Study of Ageing (n=5,766)

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Genome-Wide Meta-Analyses Of Stratified Depression In Generation Scotland And UK Biobank

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Psychosis and the level of mood incongruence in Bipolar Disorder are related to genetic liability for Schizophrenia

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Genetic and environmental risk for chronic pain and the contribution of risk variants for psychiatric disorders. Results from Generation Scotland: Scottish Family Health Study and UK Biobank

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Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

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Stratifying depression by neuroticism: revisiting a diagnostic tradition using GWAS data

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Electronic Health Record and Genome-wide Genetic Data in Generation Scotland Participants

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DNA methylation age acceleration and risk factors for Alzheimer's disease

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Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

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Epigenetic clocks predict prevalence and incidence of leading causes of death and disease burden

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An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort 1936.

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Meta-analysis of exome array data identifies six novel genetic loci for lung function

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Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism

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Rare disruptive variants in the DISC1 Interactome and Regulome: association with cognitive ability and schizophrenia

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The influence of X chromosome variants on trait neuroticism.

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Epigenetic signatures of starting and stopping smoking

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Shared genetics and couple-associated environment are major contributors to the risk of both clinical and self-declared depression

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Assessment of DNA methylation differences between carriers of APOE ε4 and APOE ε2

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DNA methylation in the APOE gene: its link with Alzheimer's and cardiovascular health

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Subthreshold psychosis symptoms associated with molecular genetic risk in a population-based cohort: Findings from Generation Scotland

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