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Author: Andrew M McIntosh

Rankings

  • All-time downloads: 130,545 (rank: 622 )
  • Categories:
    • bioinformatics: 1,553 (rank: 8,973 (tie) )
    • epidemiology: 1,394 (rank: 6,471 (tie) )
    • genetic and genomic medicine: 4,999 (rank: 105 )
    • genetics: 59,547 (rank: 58 )
    • genomics: 20,572 (rank: 500 )
    • neuroscience: 36,319 (rank: 81 )
    • psychiatry and clinical psychology: 6,161 (rank: 64 )

Downloads per author, site-wide

Preprints

Sex Differences In The Adult Human Brain: Evidence From 5,216 UK Biobank Participants

neuroscience more details view paper
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    • Site-wide: 252
    • In neuroscience: 7
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Genomewide association study identifies 30 loci associated with bipolar disorder

genetics more details view paper
  • Downloaded 7,266 times
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    • Site-wide: 1,137
    • In genetics: 38
  • Year to date:
    • Site-wide: 16,500
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    • Site-wide: 14,912

Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

genomics more details view paper
  • Downloaded 4,718 times
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    • Site-wide: 2,025
    • In genomics: 215
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    • Site-wide: 9,914

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

genetics more details view paper
  • Downloaded 4,504 times
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    • Site-wide: 2,161
    • In genetics: 83
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    • Site-wide: 19,793

Genomic SEM Provides Insights into the Multivariate Genetic Architecture of Complex Traits

genetics more details view paper
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    • Site-wide: 2,192
    • In genetics: 85
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    • Site-wide: 18,474

Genomic analysis of family data reveals additional genetic effects on intelligence and personality

genetics more details view paper
  • Downloaded 4,178 times
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    • Site-wide: 2,396
    • In genetics: 94
  • Year to date:
    • Site-wide: 23,001
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    • Site-wide: 21,859

Greater male than female variability in regional brain structure across the lifespan

neuroscience more details view paper
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    • Site-wide: 3,006
    • In neuroscience: 231
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    • Site-wide: 11,189
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    • Site-wide: 10,619

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

genomics more details view paper
  • Downloaded 3,554 times
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    • Site-wide: 3,044
    • In genomics: 356
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Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

genetics more details view paper
  • Downloaded 3,247 times
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    • Site-wide: 3,477
    • In genetics: 149
  • Year to date:
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A Major Role for Common Genetic Variation in Anxiety Disorders

genetics more details view paper
  • Downloaded 3,118 times
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    • Site-wide: 3,689
    • In genetics: 162
  • Year to date:
    • Site-wide: 7,875
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    • Site-wide: 5,759

Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

genetics more details view paper
  • Downloaded 2,559 times
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    • Site-wide: 4,862
    • In genetics: 225
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    • Site-wide: 71,566
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Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

genomics more details view paper
  • Downloaded 2,496 times
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    • Site-wide: 5,064
    • In genomics: 592
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Mental health during the COVID-19 pandemic in two longitudinal UK population cohorts

psychiatry and clinical psychology more details view paper
  • Downloaded 2,397 times
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    • Site-wide: 5,374
    • In psychiatry and clinical psychology: 14
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    • Site-wide: 1,793
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Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

genetics more details view paper
  • Downloaded 1,867 times
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    • Site-wide: 7,735
    • In genetics: 370
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    • Site-wide: 63,009
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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

genetics more details view paper
  • Downloaded 1,779 times
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    • Site-wide: 8,331
    • In genetics: 405
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    • Site-wide: 32,166
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    • Site-wide: 26,905

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

genetics more details view paper
  • Downloaded 1,700 times
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    • Site-wide: 8,948
    • In genetics: 444
  • Year to date:
    • Site-wide: 103,221
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Genome-wide association study meta-analysis of the Alcohol Use Disorder Identification Test (AUDIT) in two population-based cohorts (N=141,932)

genetics more details view paper
  • Downloaded 1,686 times
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    • Site-wide: 9,073
    • In genetics: 447
  • Year to date:
    • Site-wide: 45,358
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    • Site-wide: 37,938

Molecular genetic contributions to social deprivation and household income in UK Biobank (n = 112,151)

genetics more details view paper
  • Downloaded 1,614 times
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    • Site-wide: 9,671
    • In genetics: 484
  • Year to date:
    • Site-wide: 63,055
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    • Site-wide: 50,296

GWAS of Depression Phenotypes in the Million Veteran Program and Meta-analysis in More than 1.2 Million Participants Yields 178 Independent Risk Loci

genetic and genomic medicine more details view paper
  • Downloaded 1,597 times
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    • Site-wide: 9,812
    • In genetic and genomic medicine: 31
  • Year to date:
    • Site-wide: 5,317
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    • Site-wide: 4,320

Genome-wide association study of over 40,000 bipolar disorder cases provides novel biological insights

psychiatry and clinical psychology more details view paper
  • Downloaded 1,557 times
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    • Site-wide: 10,173
    • In psychiatry and clinical psychology: 32
  • Year to date:
    • Site-wide: 2,798
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    • Site-wide: 3,556

Genetic contribution to two factors of neuroticism is associated with affluence, better health, and longer life

genetics more details view paper
  • Downloaded 1,487 times
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    • Site-wide: 10,870
    • In genetics: 536
  • Year to date:
    • Site-wide: 77,679
  • Since beginning of last month:
    • Site-wide: 61,852

Brain Aging in Major Depressive Disorder: Results from the ENIGMA Major Depressive Disorder working group

neuroscience more details view paper
  • Downloaded 1,470 times
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    • Site-wide: 11,055
    • In neuroscience: 1,248
  • Year to date:
    • Site-wide: 56,154
  • Since beginning of last month:
    • Site-wide: 94,974

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

genomics more details view paper
  • Downloaded 1,447 times
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    • Site-wide: 11,329
    • In genomics: 1,259
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    • Site-wide: 61,745
  • Since beginning of last month:
    • Site-wide: 62,322

Genetic Architecture of 11 Major Psychiatric Disorders at Biobehavioral, Functional Genomic, and Molecular Genetic Levels of Analysis

genetic and genomic medicine more details view paper
  • Downloaded 1,403 times
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    • Site-wide: 11,874
    • In genetic and genomic medicine: 39
  • Year to date:
    • Site-wide: 2,340
  • Since beginning of last month:
    • Site-wide: 1,250

116 independent genetic variants influence the neuroticism personality trait in over 329,000 UK Biobank individuals.

genetics more details view paper
  • Downloaded 1,347 times
  • Download rankings, all-time:
    • Site-wide: 12,611
    • In genetics: 634
  • Year to date:
    • Site-wide: 80,864
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    • Site-wide: 45,552

Bayesian reassessment of the epigenetic architecture of complex traits

genomics more details view paper
  • Downloaded 1,321 times
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    • Site-wide: 12,995
    • In genomics: 1,417
  • Year to date:
    • Site-wide: 105,604
  • Since beginning of last month:
    • Site-wide: 65,426

Improved prediction of chronological age from DNA methylation limits it as a biomarker of ageing

bioinformatics more details view paper
  • Downloaded 1,300 times
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    • Site-wide: 13,296
    • In bioinformatics: 1,639
  • Year to date:
    • Site-wide: 40,859
  • Since beginning of last month:
    • Site-wide: 32,727

Genetic stratification of depression in UK Biobank suggests a subgroup linked to age of natural menopause

genetics more details view paper
  • Downloaded 1,199 times
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    • Site-wide: 15,042
    • In genetics: 773
  • Year to date:
    • Site-wide: 55,990
  • Since beginning of last month:
    • Site-wide: 42,753

Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

genetics more details view paper
  • Downloaded 1,187 times
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    • Site-wide: 15,261
    • In genetics: 783
  • Year to date:
    • Site-wide: 36,356
  • Since beginning of last month:
    • Site-wide: 33,720

Subcortical volume and white matter integrity abnormalities in major depressive disorder: findings from UK Biobank imaging data

neuroscience more details view paper
  • Downloaded 1,073 times
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    • Site-wide: 17,743
    • In neuroscience: 2,237
  • Year to date:
    • Site-wide: 92,467
  • Since beginning of last month:
    • Site-wide: 82,824

Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

genetics more details view paper
  • Downloaded 1,054 times
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    • Site-wide: 18,233
    • In genetics: 918
  • Year to date:
    • Site-wide: 5,420
  • Since beginning of last month:
    • Site-wide: 4,413

Rare loss-of-function variants in KMT2F are associated with schizophrenia and developmental disorders

genomics more details view paper
  • Downloaded 1,015 times
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    • Site-wide: 19,318
    • In genomics: 1,979
  • Year to date:
    • Site-wide: 77,618
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    • Site-wide: 75,044

Cortical Thickness Trajectories across the Lifespan: Data from 17,075 healthy individuals aged 3-90 years

neuroscience more details view paper
  • Downloaded 994 times
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    • Site-wide: 19,893
    • In neuroscience: 2,548
  • Year to date:
    • Site-wide: 13,064
  • Since beginning of last month:
    • Site-wide: 7,826

Rare schizophrenia risk variants are enriched in genes shared with neurodevelopmental disorders

genetics more details view paper
  • Downloaded 989 times
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    • Site-wide: 20,036
    • In genetics: 994
  • Year to date:
    • Site-wide: 103,436
  • Since beginning of last month:
    • Site-wide: 89,315

Epigenetic prediction of complex traits and death

genomics more details view paper
  • Downloaded 982 times
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    • Site-wide: 20,240
    • In genomics: 2,044
  • Year to date:
    • Site-wide: 81,190
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    • Site-wide: 98,374

Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

genetics more details view paper
  • Downloaded 893 times
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    • Site-wide: 23,236
    • In genetics: 1,151
  • Year to date:
    • Site-wide: 3,596
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    • Site-wide: 2,792

Is there association between APOE e4 genotype and structural brain ageing phenotypes, and does that association increase in older age in UK Biobank? (N = 8,395)

genetics more details view paper
  • Downloaded 884 times
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    • Site-wide: 23,597
    • In genetics: 1,167
  • Year to date:
    • Site-wide: 63,020
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    • Site-wide: 45,651

Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

genetics more details view paper
  • Downloaded 860 times
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    • Site-wide: 24,525
    • In genetics: 1,217
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    • Site-wide: 92,236
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A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

genetics more details view paper
  • Downloaded 857 times
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    • Site-wide: 24,657
    • In genetics: 1,224
  • Year to date:
    • Site-wide: 105,060
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    • Site-wide: 95,614

Factors associated with sharing email information and mental health survey participation in large population cohorts

genetics more details view paper
  • Downloaded 745 times
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    • Site-wide: 29,895
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    • Site-wide: 70,570
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    • Site-wide: 49,718

Do Regional Brain Volumes and Major Depressive Disorder Share Genetic Architecture: a study in Generation Scotland (n=19,762), UK Biobank (n=24,048) and the English Longitudinal Study of Ageing (n=5,766)

genetics more details view paper
  • Downloaded 743 times
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    • Site-wide: 30,035
    • In genetics: 1,485
  • Year to date:
    • Site-wide: 76,551
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    • Site-wide: 61,807

Psychosis and the level of mood incongruence in Bipolar Disorder are related to genetic liability for Schizophrenia

genetics more details view paper
  • Downloaded 732 times
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    • Site-wide: 30,653
    • In genetics: 1,524
  • Year to date:
    • Site-wide: 69,950
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Educational attainment impacts drinking behaviors and risk for alcohol dependence: results from a two-sample Mendelian randomization study with ~780 000 participants

epidemiology more details view paper
  • Downloaded 730 times
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    • Site-wide: 30,802
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    • Site-wide: 32,808

Genome-Wide Meta-Analyses Of Stratified Depression In Generation Scotland And UK Biobank

genetics more details view paper
  • Downloaded 724 times
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    • Site-wide: 31,130
    • In genetics: 1,545
  • Year to date:
    • Site-wide: 105,341
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    • Site-wide: 98,026

Epigenetic clocks predict prevalence and incidence of leading causes of death and disease burden

genomics more details view paper
  • Downloaded 724 times
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    • Site-wide: 31,168
    • In genomics: 2,828
  • Year to date:
    • Site-wide: 16,319
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    • Site-wide: 13,101

Subcortical Volume Trajectories across the Lifespan: Data from 18,605 healthy individuals aged 3-90 years

neuroscience more details view paper
  • Downloaded 710 times
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    • Site-wide: 31,981
    • In neuroscience: 4,459
  • Year to date:
    • Site-wide: 19,970
  • Since beginning of last month:
    • Site-wide: 15,280

Stratifying depression by neuroticism: revisiting a diagnostic tradition using GWAS data

genetics more details view paper
  • Downloaded 662 times
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    • Site-wide: 35,191
    • In genetics: 1,722
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    • Site-wide: 70,971
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    • Site-wide: 51,892

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

genetics more details view paper
  • Downloaded 633 times
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    • Site-wide: 37,287
    • In genetics: 1,816
  • Year to date:
    • Site-wide: 15,110
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    • Site-wide: 6,622

Genetic and environmental risk for chronic pain and the contribution of risk variants for psychiatric disorders. Results from Generation Scotland: Scottish Family Health Study and UK Biobank

genomics more details view paper
  • Downloaded 628 times
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    • Site-wide: 37,679
    • In genomics: 3,224
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    • Site-wide: None
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    • Site-wide: None

A validation of the diathesis-stress model for depression in Generation Scotland.

genomics more details view paper
  • Downloaded 622 times
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    • Site-wide: 38,163
    • In genomics: 3,258
  • Year to date:
    • Site-wide: 71,171
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    • Site-wide: 62,440

Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

genetic and genomic medicine more details view paper
  • Downloaded 602 times
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    • Site-wide: 39,746
    • In genetic and genomic medicine: 113
  • Year to date:
    • Site-wide: 8,527
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    • Site-wide: 13,469

Genome-wide association analysis links multiple psychiatric liability genes to oscillatory brain activity

genetics more details view paper
  • Downloaded 575 times
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    • Site-wide: 42,045
    • In genetics: 2,021
  • Year to date:
    • Site-wide: 103,137
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    • Site-wide: 78,407

A meta-analysis of genome-wide association studies of epigenetic age acceleration

genetics more details view paper
  • Downloaded 564 times
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    • Site-wide: 43,107
    • In genetics: 2,075
  • Year to date:
    • Site-wide: 122,810
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    • Site-wide: None

DNA methylation age acceleration and risk factors for Alzheimer's disease

genomics more details view paper
  • Downloaded 560 times
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    • Site-wide: 43,482
    • In genomics: 3,569
  • Year to date:
    • Site-wide: 109,243
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    • Site-wide: 90,358

Three major dimensions of human brain cortical ageing in relation to cognitive decline across the 8th decade of life.

neuroscience more details view paper
  • Downloaded 557 times
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    • Site-wide: 43,826
    • In neuroscience: 6,390
  • Year to date:
    • Site-wide: 39,005
  • Since beginning of last month:
    • Site-wide: 30,037

CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake

genetics more details view paper
  • Downloaded 541 times
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    • Site-wide: 45,403
    • In genetics: 2,180
  • Year to date:
    • Site-wide: 109,103
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    • Site-wide: None

Familial t(1;11) translocation is associated with disruption of white matter structural integrity and oligodendrocyte-myelin dysfunction

neuroscience more details view paper
  • Downloaded 501 times
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    • Site-wide: 49,732
    • In neuroscience: 7,390
  • Year to date:
    • Site-wide: 62,186
  • Since beginning of last month:
    • Site-wide: 92,253

Resting-state connectivity and its association with cognitive performance, educational attainment, and household income in UK Biobank (N = 3,950)

neuroscience more details view paper
  • Downloaded 460 times
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    • Site-wide: 54,743
    • In neuroscience: 8,212
  • Year to date:
    • Site-wide: 119,977
  • Since beginning of last month:
    • Site-wide: 103,731

A genome-wide association study finds genetic variants associated with neck or shoulder pain in UK Biobank

genetics more details view paper
  • Downloaded 449 times
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    • Site-wide: 56,180
    • In genetics: 2,665
  • Year to date:
    • Site-wide: 46,390
  • Since beginning of last month:
    • Site-wide: 29,877

Genome-wide by environment interaction studies (GWEIS) of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland.

genetics more details view paper
  • Downloaded 425 times
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    • Site-wide: 59,441
    • In genetics: 2,820
  • Year to date:
    • Site-wide: 47,603
  • Since beginning of last month:
    • Site-wide: 28,985

Birth weight associations with psychiatric and physical health, cognitive function, and DNA methylation differences in an adult population

genomics more details view paper
  • Downloaded 425 times
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    • Site-wide: 59,434
    • In genomics: 4,423
  • Year to date:
    • Site-wide: 101,367
  • Since beginning of last month:
    • Site-wide: 81,012

Sex-Stratified Genome-Wide Association Study of Multisite Chronic Pain in UK Biobank

genetic and genomic medicine more details view paper
  • Downloaded 424 times
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    • Site-wide: 59,550
    • In genetic and genomic medicine: 175
  • Year to date:
    • Site-wide: 12,785
  • Since beginning of last month:
    • Site-wide: 20,659

Genetic variation in the Major Histocompatibility Complex and association with depression

genetics more details view paper
  • Downloaded 422 times
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    • Site-wide: 59,842
    • In genetics: 2,832
  • Year to date:
    • Site-wide: 108,926
  • Since beginning of last month:
    • Site-wide: 74,224

A genome-wide association study finds novel genetic associations with broadly-defined headache in UK Biobank (N = 223,773)

genetics more details view paper
  • Downloaded 415 times
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    • Site-wide: 60,920
    • In genetics: 2,888
  • Year to date:
    • Site-wide: 87,468
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    • Site-wide: 78,384

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

genetic and genomic medicine more details view paper
  • Downloaded 414 times
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    • Site-wide: 60,945
    • In genetic and genomic medicine: 182
  • Year to date:
    • Site-wide: 10,955
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    • Site-wide: 17,772

Childhood intelligence attenuates the association between biological ageing and health outcomes in later life

genomics more details view paper
  • Downloaded 406 times
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    • Site-wide: 62,282
    • In genomics: 4,551
  • Year to date:
    • Site-wide: 113,680
  • Since beginning of last month:
    • Site-wide: 88,843

Genetic correlations between pain phenotypes and depression and neuroticism

genetics more details view paper
  • Downloaded 406 times
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    • Site-wide: 62,283
    • In genetics: 2,944
  • Year to date:
    • Site-wide: 96,370
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    • Site-wide: 62,057

Rare disruptive variants in the DISC1 Interactome and Regulome: association with cognitive ability and schizophrenia

genetics more details view paper
  • Downloaded 402 times
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    • Site-wide: 62,973
    • In genetics: 2,968
  • Year to date:
    • Site-wide: 76,812
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    • Site-wide: None

Epigenetic prediction of major depressive disorder

psychiatry and clinical psychology more details view paper
  • Downloaded 401 times
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    • Site-wide: 63,103
    • In psychiatry and clinical psychology: 188
  • Year to date:
    • Site-wide: 120,795
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    • Site-wide: 88,009

Cognitive functioning and lifetime Major Depressive Disorder in UK Biobank

psychiatry and clinical psychology more details view paper
  • Downloaded 394 times
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    • Site-wide: 64,038
    • In psychiatry and clinical psychology: 192
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    • Site-wide: 68,531
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    • Site-wide: 68,344

DISC1 regulates N-Methyl-D-Aspartate receptor dynamics: Abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness

neuroscience more details view paper
  • Downloaded 392 times
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    • Site-wide: 64,332
    • In neuroscience: 9,835
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    • Site-wide: 92,344
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    • Site-wide: 77,705

Characterisation of an inflammation-related epigenetic score and its association with cognitive ability

genomics more details view paper
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Genome-wide association study of circadian rhythmicity in 71 500 UK Biobank participants and polygenic association with mood instability

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Mental Health in UK Biobank Revised

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Psychotic-like experiences, polygenic risk scores for schizophrenia and structural properties of the salience, default mode and central-executive networks in healthy participants from UK Biobank

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The influence of X chromosome variants on trait neuroticism.

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An epigenetic predictor of death captures multi-modal measures of brain health

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Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2

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Identification of polymorphic and off-target probe binding sites on the Illumina Infinium MethylationEPIC BeadChip

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Epigenome-wide analyses identify DNA methylation signatures of dementia risk

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Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

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Association of whole-genome and NETRIN1 signaling pathway-derived polygenic risk scores for Major Depressive Disorder and thalamic radiation white matter microstructure in UK Biobank

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Antidepressant Response in Major Depressive Disorder: A Genome-wide Association Study

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Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell counts and epigenetic ageing

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A genome-wide association study identifies that the GDF5 and COL27A1 genes are associated with knee pain in UK Biobank (N = 171, 516)

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Shared genetics and couple-associated environment are major contributors to the risk of both clinical and self-declared depression

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Assessment of Dried Blood Spots for DNA Methylation Profiling

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Expression quantitative trait loci-derived scores and white matter microstructure in UK Biobank: a novel approach to integrating genetics and neuroimaging

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DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

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Brain correlates of suicide attempt in 18,925 participants across 18 international cohorts

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Stratifying major depressive disorder by polygenic risk for schizophrenia in relation to structural brain measures

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Creating and validating a DNA methylation-based proxy for Interleukin-6

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DNA methylation in the APOE gene: its link with Alzheimer's and cardiovascular health

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DNA methylation proxies for 16 plasma proteins predict the incidence of 7 leading causes of morbidity

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DNA methylation signatures of C-reactive protein associations with structural neuroimaging measures and major depressive disorder

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Subthreshold psychosis symptoms associated with molecular genetic risk in a population-based cohort: Findings from Generation Scotland

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White matter microstructure and its relation to longitudinal measures of depressive symptoms in mid-late life

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Associations between alcohol use and accelerated biological ageing

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Associations Between Major Psychiatric Disorder Polygenic Risk Scores and Blood-Based Markers in UK Biobank

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The Influence of Phenotyping Method on Neuroimaging Associations with Depression in UK Biobank

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Comparison of algorithm-based versus single-item phenotyping measures of depression and anxiety disorders in the GLAD Study cohort

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A comparison of blood and brain-derived ageing and inflammation-related DNA methylation signatures and their association with microglial burdens

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Epigenome-wide association study of self-reported antidepressant use in Generation Scotland implicates the innate immune system

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Omics versus Questionnaires: Using methylation data to assess the environmental impact of smoking on obesity-related traits

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Experience of clinical services shapes attitudes to data sharing

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