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Author: Andrew M. McIntosh

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    • bioinformatics: 1,477 (rank: 8,562 (tie) out of 36,785)
    • epidemiology: 942 (rank: 1,726 (tie) out of 9,545)
    • genetics: 56,980 (rank: 59 out of 38,573)
    • genomics: 19,582 (rank: 486 out of 45,497)
    • neuroscience: 34,920 (rank: 75 out of 73,518)

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Preprints

Sex Differences In The Adult Human Brain: Evidence From 5,216 UK Biobank Participants

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Genomewide association study identifies 30 loci associated with bipolar disorder

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Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

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Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

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Genomic SEM Provides Insights into the Multivariate Genetic Architecture of Complex Traits

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Genomic analysis of family data reveals additional genetic effects on intelligence and personality

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Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

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Greater male than female variability in regional brain structure across the lifespan

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Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

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A Major Role for Common Genetic Variation in Anxiety Disorders

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Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

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Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

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Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

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Genome-wide association study meta-analysis of the Alcohol Use Disorder Identification Test (AUDIT) in two population-based cohorts (N=141,932)

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Molecular genetic contributions to social deprivation and household income in UK Biobank (n = 112,151)

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Genetic contribution to two factors of neuroticism is associated with affluence, better health, and longer life

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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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Brain Aging in Major Depressive Disorder: Results from the ENIGMA Major Depressive Disorder working group

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116 independent genetic variants influence the neuroticism personality trait in over 329,000 UK Biobank individuals.

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Bayesian reassessment of the epigenetic architecture of complex traits

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Improved prediction of chronological age from DNA methylation limits it as a biomarker of ageing

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Genetic stratification of depression in UK Biobank suggests a subgroup linked to age of natural menopause

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Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

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Subcortical volume and white matter integrity abnormalities in major depressive disorder: findings from UK Biobank imaging data

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Rare loss-of-function variants in KMT2F are associated with schizophrenia and developmental disorders

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Rare schizophrenia risk variants are enriched in genes shared with neurodevelopmental disorders

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Epigenetic prediction of complex traits and death

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Is there association between APOE e4 genotype and structural brain ageing phenotypes, and does that association increase in older age in UK Biobank? (N = 8,395)

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Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

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A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

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Cortical Thickness Trajectories across the Lifespan: Data from 17,075 healthy individuals aged 3-90 years

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Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

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Do Regional Brain Volumes and Major Depressive Disorder Share Genetic Architecture: a study in Generation Scotland (n=19,762), UK Biobank (n=24,048) and the English Longitudinal Study of Ageing (n=5,766)

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Factors associated with sharing email information and mental health survey participation in large population cohorts

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Genome-Wide Meta-Analyses Of Stratified Depression In Generation Scotland And UK Biobank

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Psychosis and the level of mood incongruence in Bipolar Disorder are related to genetic liability for Schizophrenia

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Educational attainment impacts drinking behaviors and risk for alcohol dependence: results from a two-sample Mendelian randomization study with ~780 000 participants

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Stratifying depression by neuroticism: revisiting a diagnostic tradition using GWAS data

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Genetic and environmental risk for chronic pain and the contribution of risk variants for psychiatric disorders. Results from Generation Scotland: Scottish Family Health Study and UK Biobank

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Epigenetic clocks predict prevalence and incidence of leading causes of death and disease burden

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A validation of the diathesis-stress model for depression in Generation Scotland.

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Subcortical Volume Trajectories across the Lifespan: Data from 18,605 healthy individuals aged 3-90 years

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Genome-wide association analysis links multiple psychiatric liability genes to oscillatory brain activity

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A meta-analysis of genome-wide association studies of epigenetic age acceleration

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DNA methylation age acceleration and risk factors for Alzheimer's disease

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Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

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Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

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CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake

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Three major dimensions of human brain cortical ageing in relation to cognitive decline across the 8th decade of life.

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Familial t(1;11) translocation is associated with disruption of white matter structural integrity and oligodendrocyte-myelin dysfunction

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Resting-state connectivity and its association with cognitive performance, educational attainment, and household income in UK Biobank (N = 3,950)

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Birth weight associations with psychiatric and physical health, cognitive function, and DNA methylation differences in an adult population

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Genetic variation in the Major Histocompatibility Complex and association with depression

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A genome-wide association study finds genetic variants associated with neck or shoulder pain in UK Biobank

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A genome-wide association study finds novel genetic associations with broadly-defined headache in UK Biobank (N = 223,773)

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Childhood intelligence attenuates the association between biological ageing and health outcomes in later life

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Genetic correlations between pain phenotypes and depression and neuroticism

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Genome-wide by environment interaction studies (GWEIS) of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland.

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Rare disruptive variants in the DISC1 Interactome and Regulome: association with cognitive ability and schizophrenia

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Characterisation of an inflammation-related epigenetic score and its association with cognitive ability

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DISC1 regulates N-Methyl-D-Aspartate receptor dynamics: Abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness

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Genome-wide association study of circadian rhythmicity in 71 500 UK Biobank participants and polygenic association with mood instability

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Psychotic-like experiences, polygenic risk scores for schizophrenia and structural properties of the salience, default mode and central-executive networks in healthy participants from UK Biobank

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The influence of X chromosome variants on trait neuroticism.

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An epigenetic predictor of death captures multi-modal measures of brain health

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Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

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Identification of polymorphic and off-target probe binding sites on the Illumina Infinium MethylationEPIC BeadChip

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Association of whole-genome and NETRIN1 signaling pathway-derived polygenic risk scores for Major Depressive Disorder and thalamic radiation white matter microstructure in UK Biobank

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Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2

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Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell counts and epigenetic ageing

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A genome-wide association study identifies that the GDF5 and COL27A1 genes are associated with knee pain in UK Biobank (N = 171, 516)

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Shared genetics and couple-associated environment are major contributors to the risk of both clinical and self-declared depression

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Assessment of Dried Blood Spots for DNA Methylation Profiling

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Expression quantitative trait loci-derived scores and white matter microstructure in UK Biobank: a novel approach to integrating genetics and neuroimaging

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Stratifying major depressive disorder by polygenic risk for schizophrenia in relation to structural brain measures

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DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

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DNA methylation in the APOE gene: its link with Alzheimer's and cardiovascular health

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White matter microstructure and its relation to longitudinal measures of depressive symptoms in mid-late life

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Subthreshold psychosis symptoms associated with molecular genetic risk in a population-based cohort: Findings from Generation Scotland

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Omics versus Questionnaires: Using methylation data to assess the environmental impact of smoking on obesity-related traits

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