Author: Neil M Davies

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Preprints

Collider bias undermines our understanding of COVID-19 disease risk and severity

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  • Site-wide: 602
  • In epidemiology: 90
• Year to date:
  • Site-wide: 2,497
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  • Site-wide: 2,497

PHESANT: a tool for performing automated phenome scans in UK Biobank

• Downloaded 3,364 times
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  • Site-wide: 3,273
  • In epidemiology: 322
• Year to date:
  • Site-wide: 26,424
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  • Site-wide: 26,424

Genetic analysis identifies molecular systems and biological pathways associated with household income

• Downloaded 2,704 times
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  • Site-wide: 4,443
  • In genetics: 206
• Year to date:
  • Site-wide: 71,492
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  • Site-wide: 71,492

Why are education, socioeconomic position and intelligence genetically correlated?

• Downloaded 2,412 times
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  • Site-wide: 5,286
  • In genetics: 252
• Year to date:
  • Site-wide: 34,703
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  • Site-wide: 34,703

Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases

• Downloaded 2,104 times
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  • Site-wide: 6,426
  • In genetics: 320
• Year to date:
  • Site-wide: 21,279
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  • Site-wide: 21,279

Mendelian randomisation for mediation analysis: current methods and challenges for implementation

• Downloaded 1,591 times
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  • Site-wide: 9,782
  • In genetics: 493
• Year to date:
  • Site-wide: 8,868
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  • Site-wide: 8,868

The Causal Effects of Education on Health, Mortality, Cognition, Well-being, and Income in the UK Biobank

• Downloaded 1,397 times
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  • Site-wide: 11,853
  • In epidemiology: 803
• Year to date:
  • Site-wide: 44,386
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  • Site-wide: 44,386

Selection bias in instrumental variable analyses

• Downloaded 1,340 times
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  • Site-wide: 12,617
  • In epidemiology: 842
• Year to date:
  • Site-wide: 18,098
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  • Site-wide: 18,098

Searching for the causal effects of BMI in over 300 000 individuals, using Mendelian randomization

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  • Site-wide: 12,934
  • In epidemiology: 857
• Year to date:
  • Site-wide: 95,139
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  • Site-wide: 95,139

Alcohol consumption and mate choice in UK Biobank: comparing observational and Mendelian randomization estimates

• Downloaded 1,171 times
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  • Site-wide: 15,447
  • In genetics: 792
• Year to date:
  • Site-wide: 56,806
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  • Site-wide: 56,806

Mendelian randomization: a novel approach for the prediction of adverse drug events and drug repurposing opportunities

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  • Site-wide: 18,146
  • In pharmacology and toxicology: 101
• Year to date:
  • Site-wide: 99,115
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  • Site-wide: 99,115

Education, intelligence and Alzheimer's disease: Evidence from a multivariable two-sample Mendelian randomization study

• Downloaded 1,037 times
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  • Site-wide: 18,570
  • In genetics: 930
• Year to date:
  • Site-wide: 71,147
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  • Site-wide: 71,147

The effect of education on adult mortality, health, and income: triangulating across genetic and policy reforms

• Downloaded 1,007 times
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  • Site-wide: 19,422
  • In epidemiology: 1,133
• Year to date:
  • Site-wide: 85,344
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  • Site-wide: 85,344

An epigenome-wide association study of educational attainment (n = 10,767)

• Downloaded 979 times
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  • Site-wide: 20,162
  • In genetics: 1,002
• Year to date:
  • Site-wide: 52,743
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  • Site-wide: 52,743

Can education be personalised using pupils’ genetic data?

• Downloaded 935 times
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  • Site-wide: 21,508
  • In genetics: 1,064
• Year to date:
  • Site-wide: 61,879
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  • Site-wide: 61,879

The causes and consequences of Alzheimer's disease: A Mendelian randomization analysis

• Downloaded 871 times
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  • Site-wide: 23,887
  • In genetic and genomic medicine: 72
• Year to date:
  • Site-wide: 8,889
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  • Site-wide: 8,889

Software Application Profile: mrrobust - A Tool For Performing Two-Sample Summary Mendelian Randomization Analyses

• Downloaded 826 times
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  • Site-wide: 25,703
  • In epidemiology: 1,366
• Year to date:
  • Site-wide: 64,736
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  • Site-wide: 64,736

Cardiometabolic traits, sepsis and severe covid-19 with respiratory failure: a Mendelian randomization investigation

• Downloaded 818 times
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  • Site-wide: 26,057
  • In epidemiology: 1,372
• Year to date:
  • Site-wide: 13,727
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  • Site-wide: 13,727

Power calculator for instrumental variable analysis in pharmacoepidemiology

• Downloaded 816 times
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  • Site-wide: 26,140
  • In epidemiology: 1,376
• Year to date:
  • Site-wide: 85,654
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  • Site-wide: 85,654

Cleft lip/palate and educational attainment: cause, consequence, or correlation? A Mendelian randomization study

• Downloaded 753 times
• Download rankings, all-time:
  • Site-wide: 29,265
  • In genetics: 1,457
• Year to date:
  • Site-wide: 34,731
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  • Site-wide: 34,731

Examining the genetic influences of educational attainment and the validity of value-added measures of progress

• Downloaded 733 times
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  • Site-wide: 30,327
  • In genetics: 1,510
• Year to date:
  • Site-wide: 105,263
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  • Site-wide: 105,263

Repurposing antihypertensive drugs for the prevention of Alzheimer’s disease: a Mendelian Randomization study

• Downloaded 701 times
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  • Site-wide: 32,264
  • In genetics: 1,608
• Year to date:
  • Site-wide: 76,003
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  • Site-wide: 76,003

The molecular genetics of participation in the Avon Longitudinal Study of Parents and Children

• Downloaded 664 times
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  • Site-wide: 34,715
  • In genetics: 1,705
• Year to date:
  • Site-wide: 111,011
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  • Site-wide: 111,011

Consistency of non-cognitive skills and their relation to educational outcomes in a UK cohort

• Downloaded 655 times
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  • Site-wide: 35,344
  • In genetics: 1,738
• Year to date:
  • Site-wide: 25,683
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  • Site-wide: 25,683

Using genetic instruments to estimate interactions in Mendelian Randomization studies

• Downloaded 576 times
• Download rankings, all-time:
  • Site-wide: 41,623
  • In epidemiology: 1,941
• Year to date:
  • Site-wide: 44,408
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  • Site-wide: 44,408

What explains the effect of education on cardiovascular disease? Applying Mendelian randomization to identify the consequences of education inequality

• Downloaded 500 times
• Download rankings, all-time:
  • Site-wide: 49,382
  • In epidemiology: 2,185
• Year to date:
  • Site-wide: 99,247
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  • Site-wide: 99,247

The causal effect of adiposity on hospital costs: Mendelian Randomization analysis of over 300,000 individuals from the UK Biobank

• Downloaded 459 times
• Download rankings, all-time:
  • Site-wide: 54,381
  • In epidemiology: 2,338
• Year to date:
  • Site-wide: 70,527
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  • Site-wide: 70,527

Comparison of antihypertensive drug classes for dementia prevention

• Downloaded 449 times
• Download rankings, all-time:
  • Site-wide: 55,699
  • In epidemiology: 2,382
• Year to date:
  • Site-wide: 83,690
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  • Site-wide: 83,690

Are there causal relationships between ADHD and BMI? Evidence from multiple genetically informed designs

• Downloaded 443 times
• Download rankings, all-time:
  • Site-wide: 56,521
  • In psychiatry and clinical psychology: 168
• Year to date:
  • Site-wide: 41,258
• Since beginning of last month:
  • Site-wide: 41,258

Schizophrenia risk and reproductive success: A Mendelian randomization study.

• Downloaded 423 times
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  • Site-wide: 59,273
  • In evolutionary biology: 3,328
• Year to date:
  • Site-wide: 83,766
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  • Site-wide: 83,766

Is genetic liability to ADHD and ASD causally linked to educational attainment?

• Downloaded 422 times
• Download rankings, all-time:
  • Site-wide: 59,437
  • In genetics: 2,821
• Year to date:
  • Site-wide: 29,927
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  • Site-wide: 29,927

The Causal Effects of Health Conditions and Risk Factors on Social and Socioeconomic Outcomes: Mendelian Randomization in UK Biobank

• Downloaded 420 times
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  • Site-wide: 59,735
  • In public and global health: 697
• Year to date:
  • Site-wide: 79,303
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  • Site-wide: 79,303

Testing the causal effects between subjective wellbeing and physical health using Mendelian randomisation

• Downloaded 392 times
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  • Site-wide: 63,955
  • In epidemiology: 2,700
• Year to date:
  • Site-wide: 50,179
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  • Site-wide: 50,179

Assortative mating and within-spouse pair comparisons

• Downloaded 339 times
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  • Site-wide: 72,821
  • In genetics: 3,397
• Year to date:
  • Site-wide: 86,472
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  • Site-wide: 86,472

Estimating the causal effect of genetic liability to prevalent disease on hospital costs using Mendelian Randomization

• Downloaded 299 times
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  • Site-wide: 80,394
  • In health economics: 95
• Year to date:
  • Site-wide: 35,683
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  • Site-wide: 35,683

Common health conditions in childhood and adolescence, school absence, and educational attainment: Mendelian randomization study

• Downloaded 274 times
• Download rankings, all-time:
  • Site-wide: 85,432
  • In epidemiology: 3,492
• Year to date:
  • Site-wide: 59,257
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  • Site-wide: 59,257

The relationship between open angle glaucoma, optic disc morphology and Alzheimer's Disease: a Mendelian randomization study

• Downloaded 266 times
• Download rankings, all-time:
  • Site-wide: 87,121
  • In ophthalmology: 60
• Year to date:
  • Site-wide: 50,742
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  • Site-wide: 50,742

Educational inequalities in statin treatment for preventing cardiovascular disease: cross-sectional analysis of UK Biobank

• Downloaded 255 times
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  • Site-wide: 89,566
  • In epidemiology: 3,635
• Year to date:
  • Site-wide: 55,778
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  • Site-wide: 55,778

The consequences of adjustment, correction and selection in genome-wide association studies used for two-sample Mendelian randomization

• Downloaded 247 times
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  • Site-wide: 91,201
  • In epidemiology: 3,697
• Year to date:
  • Site-wide: 15,241
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  • Site-wide: 15,241

Blood Pressure and Risk of Atrial Fibrillation: A Mendelian Randomization Study

• Downloaded 186 times
• Download rankings, all-time:
  • Site-wide: 104,448
  • In cardiovascular medicine: 212
• Year to date:
  • Site-wide: 39,306
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  • Site-wide: 39,306

Robust causal inference for long-term policy decisions: cost effectiveness of interventions for obesity using Mendelian randomization

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  • Site-wide: 106,672
  • In epidemiology: 4,346
• Year to date:
  • Site-wide: 100,827
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  • Site-wide: 100,827

Genetic Variation in Blood Pressure and Lifetime Risk of Peripheral Artery Disease: A Mendelian Randomization Study

• Downloaded 165 times
• Download rankings, all-time:
  • Site-wide: 108,751
  • In cardiovascular medicine: 232
• Year to date:
  • Site-wide: 51,730
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  • Site-wide: 51,730

Interpreting Mendelian randomization estimates of the effects of categorical exposures such as disease status and educational attainment

• Downloaded 124 times
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  • Site-wide: 116,600
  • In epidemiology: 4,718
• Year to date:
  • Site-wide: 36,035
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  • Site-wide: 36,035

Testosterone and socioeconomic position: Mendelian Randomization in 306,248 men and women participants of UK Biobank

• Downloaded 119 times
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  • Site-wide: 117,363
  • In epidemiology: 4,743
• Year to date:
  • Site-wide: 80,230
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  • Site-wide: 80,230