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Author: George Davey Smith

Rankings

  • All-time downloads: 210,485 (rank: 230 )
  • Categories:
    • bioinformatics: 2,315 (rank: 5,609 (tie) )
    • cardiovascular medicine: 1,093 (rank: 319 (tie) )
    • epidemiology: 129,696 (rank: 97 )
    • evolutionary biology: 414 (rank: 14,400 (tie) )
    • genetic and genomic medicine: 3,003 (rank: 206 (tie) )
    • genetics: 66,377 (rank: 47 )
    • genomics: 3,330 (rank: 6,818 )
    • health economics: 279 (rank: 361 (tie) )
    • neurology: 305 (rank: 2,505 (tie) )
    • neuroscience: 500 (rank: 39,455 (tie) )
    • ophthalmology: 253 (rank: 355 (tie) )
    • pharmacology and toxicology: 1,051 (rank: 934 (tie) )
    • psychiatry and clinical psychology: 440 (rank: 1,636 (tie) )
    • respiratory medicine: 245 (rank: 1,704 )
    • systems biology: 1,184 (rank: 3,289 )

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Preprints

An Informatics Consult approach for generating clinical evidence for treatment decisions

health informatics more details view paper

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Puberty and sex-specific trajectories of systolic blood pressure: a prospective cohort study

epidemiology more details view paper

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Selection into shift work is influenced by educational attainment and body mass index: A Mendelian randomization study

epidemiology more details view paper
  • Downloaded 61,419 times
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    • Site-wide: 78
    • In epidemiology: 17
  • Year to date:
    • Site-wide: 85,629
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    • Site-wide: 66

Collider bias undermines our understanding of COVID-19 disease risk and severity

epidemiology more details view paper
  • Downloaded 11,501 times
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    • Site-wide: 576
    • In epidemiology: 86
  • Year to date:
    • Site-wide: 2,960
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    • Site-wide: 1,594

A reference panel of 64,976 haplotypes for genotype imputation

genetics more details view paper
  • Downloaded 4,562 times
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    • Site-wide: 1,988
    • In genetics: 80
  • Year to date:
    • Site-wide: 104,423
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    • Site-wide: 60,320

MR-Base: a platform for systematic causal inference across the phenome using billions of genetic associations

epidemiology more details view paper
  • Downloaded 3,919 times
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    • Site-wide: 2,476
    • In epidemiology: 250
  • Year to date:
    • Site-wide: 39,320
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Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

genetics more details view paper
  • Downloaded 3,634 times
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    • Site-wide: 2,757
    • In genetics: 111
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    • Site-wide: 15,181
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    • Site-wide: 10,772

PHESANT: a tool for performing automated phenome scans in UK Biobank

epidemiology more details view paper
  • Downloaded 3,359 times
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    • Site-wide: 3,111
    • In epidemiology: 293
  • Year to date:
    • Site-wide: 9,925
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    • Site-wide: 20,065

Automating Mendelian randomization through machine learning to construct a putative causal map of the human phenome

epidemiology more details view paper
  • Downloaded 3,261 times
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    • Site-wide: 3,254
    • In epidemiology: 308
  • Year to date:
    • Site-wide: 22,409
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    • Site-wide: 12,203

Collider Scope: When selection bias can substantially influence observed associations

epidemiology more details view paper
  • Downloaded 2,591 times
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    • Site-wide: 4,515
    • In epidemiology: 388
  • Year to date:
    • Site-wide: 21,665
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    • Site-wide: 44,825

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

genetics more details view paper
  • Downloaded 2,489 times
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    • Site-wide: 4,780
    • In genetics: 231
  • Year to date:
    • Site-wide: 91,855
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    • Site-wide: 94,842

Genome-wide association study identifies 48 common genetic variants associated with handedness

genetics more details view paper
  • Downloaded 2,476 times
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    • Site-wide: 4,820
    • In genetics: 233
  • Year to date:
    • Site-wide: 18,572
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    • Site-wide: 15,714

Mendelian randomization: a premature burial?

genetics more details view paper
  • Downloaded 2,405 times
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    • Site-wide: 5,056
    • In genetics: 241
  • Year to date:
    • Site-wide: 15,387
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    • Site-wide: 45,203

Why are education, socioeconomic position and intelligence genetically correlated?

genetics more details view paper
  • Downloaded 2,385 times
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    • Site-wide: 5,112
    • In genetics: 247
  • Year to date:
    • Site-wide: 67,164
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Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders

genetics more details view paper
  • Downloaded 2,360 times
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    • Site-wide: 5,187
    • In genetics: 251
  • Year to date:
    • Site-wide: 65,310
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    • Site-wide: 82,904

Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis

epidemiology more details view paper
  • Downloaded 2,324 times
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    • Site-wide: 5,332
    • In epidemiology: 439
  • Year to date:
    • Site-wide: 52,064
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    • Site-wide: 102,253

Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases

genetics more details view paper
  • Downloaded 2,070 times
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    • Site-wide: 6,274
    • In genetics: 315
  • Year to date:
    • Site-wide: 20,564
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    • Site-wide: 23,507

Investigating causal relationships between sleep traits and risk of breast cancer: a Mendelian randomization study

epidemiology more details view paper
  • Downloaded 1,913 times
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    • Site-wide: 7,058
    • In epidemiology: 540
  • Year to date:
    • Site-wide: 107,067
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    • Site-wide: 96,123

An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome

genetics more details view paper
  • Downloaded 1,829 times
  • Download rankings, all-time:
    • Site-wide: 7,527
    • In genetics: 374
  • Year to date:
    • Site-wide: 97,573
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    • Site-wide: 56,103

Common genetic variants and health outcomes appear geographically structured in the UK Biobank sample: Old concerns returning and their implications.

genetics more details view paper
  • Downloaded 1,820 times
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    • Site-wide: 7,578
    • In genetics: 376
  • Year to date:
    • Site-wide: 59,191
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Improving the accuracy of two-sample summary data Mendelian randomization: moving beyond the NOME assumption

epidemiology more details view paper
  • Downloaded 1,731 times
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    • Site-wide: 8,184
    • In epidemiology: 598
  • Year to date:
    • Site-wide: 13,036
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    • Site-wide: 47,663

Genomic analysis of diet composition finds novel loci and associations with health and lifestyle

genetics more details view paper
  • Downloaded 1,719 times
  • Download rankings, all-time:
    • Site-wide: 8,275
    • In genetics: 417
  • Year to date:
    • Site-wide: 112,282
  • Since beginning of last month:
    • Site-wide: 71,207

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

genetics more details view paper
  • Downloaded 1,698 times
  • Download rankings, all-time:
    • Site-wide: 8,435
    • In genetics: 425
  • Year to date:
    • Site-wide: 54,587
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    • Site-wide: 59,742

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

genetics more details view paper
  • Downloaded 1,684 times
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    • Site-wide: 8,560
    • In genetics: 435
  • Year to date:
    • Site-wide: 106,575
  • Since beginning of last month:
    • Site-wide: 63,504

Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population

genetics more details view paper
  • Downloaded 1,657 times
  • Download rankings, all-time:
    • Site-wide: 8,781
    • In genetics: 446
  • Year to date:
    • Site-wide: 113,026
  • Since beginning of last month:
    • Site-wide: 100,761

A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

genetics more details view paper
  • Downloaded 1,619 times
  • Download rankings, all-time:
    • Site-wide: 9,110
    • In genetics: 464
  • Year to date:
    • Site-wide: 39,533
  • Since beginning of last month:
    • Site-wide: 119,680

Mendelian randomisation for mediation analysis: current methods and challenges for implementation

genetics more details view paper
  • Downloaded 1,569 times
  • Download rankings, all-time:
    • Site-wide: 9,532
    • In genetics: 488
  • Year to date:
    • Site-wide: 3,378
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    • Site-wide: 6,402

An examination of multivariable Mendelian randomization in the single sample and two-sample summary data settings.

epidemiology more details view paper
  • Downloaded 1,507 times
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    • Site-wide: 10,108
    • In epidemiology: 700
  • Year to date:
    • Site-wide: 23,636
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    • Site-wide: 44,859

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

genetics more details view paper
  • Downloaded 1,392 times
  • Download rankings, all-time:
    • Site-wide: 11,382
    • In genetics: 582
  • Year to date:
    • Site-wide: 85,846
  • Since beginning of last month:
    • Site-wide: 61,479

The Causal Effects of Education on Health, Mortality, Cognition, Well-being, and Income in the UK Biobank

epidemiology more details view paper
  • Downloaded 1,384 times
  • Download rankings, all-time:
    • Site-wide: 11,477
    • In epidemiology: 756
  • Year to date:
    • Site-wide: 35,652
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    • Site-wide: 83,622

Cigarette smoking increases coffee consumption: findings from a Mendelian randomisation analysis

genetics more details view paper
  • Downloaded 1,367 times
  • Download rankings, all-time:
    • Site-wide: 11,683
    • In genetics: 602
  • Year to date:
    • Site-wide: 32,909
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    • Site-wide: 24,743

Do early life non-cognitive skills matter? A systematic review and meta-analysis of early life effects on academic achievement, psychosocial, language and cognitive, and health outcomes

epidemiology more details view paper
  • Downloaded 1,325 times
  • Download rankings, all-time:
    • Site-wide: 12,252
    • In epidemiology: 801
  • Year to date:
    • Site-wide: 99,229
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    • Site-wide: 68,378

Selection bias in instrumental variable analyses

epidemiology more details view paper
  • Downloaded 1,311 times
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    • Site-wide: 12,447
    • In epidemiology: 813
  • Year to date:
    • Site-wide: 11,935
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    • Site-wide: 25,722

The genetic architecture of osteoarthritis: insights from UK Biobank

genetics more details view paper
  • Downloaded 1,306 times
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    • Site-wide: 12,519
    • In genetics: 639
  • Year to date:
    • Site-wide: 119,909
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    • Site-wide: 58,810

Meffil: efficient normalisation and analysis of very large DNA methylation samples

bioinformatics more details view paper
  • Downloaded 1,269 times
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    • Site-wide: 13,072
    • In bioinformatics: 1,639
  • Year to date:
    • Site-wide: 56,067
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    • Site-wide: 64,984

Systematic Mendelian randomization framework elucidates hundreds of genetic loci which may influence disease through changes in DNA methylation levels

genetics more details view paper
  • Downloaded 1,260 times
  • Download rankings, all-time:
    • Site-wide: 13,230
    • In genetics: 688
  • Year to date:
    • Site-wide: 97,773
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    • Site-wide: 111,215

Causal epigenome-wide association study identifies CpG sites that influence cardiovascular disease risk

epidemiology more details view paper
  • Downloaded 1,196 times
  • Download rankings, all-time:
    • Site-wide: 14,292
    • In epidemiology: 882
  • Year to date:
    • Site-wide: 50,552
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    • Site-wide: 117,564

Alcohol consumption and mate choice in UK Biobank: comparing observational and Mendelian randomization estimates

genetics more details view paper
  • Downloaded 1,159 times
  • Download rankings, all-time:
    • Site-wide: 14,978
    • In genetics: 775
  • Year to date:
    • Site-wide: 53,889
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    • Site-wide: 48,328

Multi-omics study revealing tissue-dependent putative mechanisms of SARS-CoV-2 drug targets on viral infections and complex diseases

genetic and genomic medicine more details view paper
  • Downloaded 1,130 times
  • Download rankings, all-time:
    • Site-wide: 15,545
    • In genetic and genomic medicine: 45
  • Year to date:
    • Site-wide: 19,594
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    • Site-wide: 18,367

Narrow-sense heritability estimation of complex traits using identity-by-descent information.

genetics more details view paper
  • Downloaded 1,112 times
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    • Site-wide: 15,954
    • In genetics: 823
  • Year to date:
    • Site-wide: 71,841
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    • Site-wide: 69,447

Bayesian network analysis incorporating genetic anchors complements conventional Mendelian randomization approaches for exploratory analysis of causal relationships in complex data

genetics more details view paper
  • Downloaded 1,101 times
  • Download rankings, all-time:
    • Site-wide: 16,207
    • In genetics: 837
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    • Site-wide: 24,401
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    • Site-wide: 91,409

Body mass index and mortality in UK Biobank: revised estimates using Mendelian randomization

epidemiology more details view paper
  • Downloaded 1,075 times
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    • Site-wide: 16,817
    • In epidemiology: 993
  • Year to date:
    • Site-wide: 101,059
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    • Site-wide: 88,114

Mendelian randomization: a novel approach for the prediction of adverse drug events and drug repurposing opportunities

pharmacology and toxicology more details view paper
  • Downloaded 1,051 times
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    • Site-wide: 17,376
    • In pharmacology and toxicology: 98
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    • Site-wide: 58,635
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    • Site-wide: 99,364

Sex-associated autosomal DNA methylation differences are wide-spread and stable throughout childhood

epidemiology more details view paper
  • Downloaded 1,050 times
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    • Site-wide: 17,409
    • In epidemiology: 1,023
  • Year to date:
    • Site-wide: 31,444
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    • Site-wide: 22,590

Education, intelligence and Alzheimer's disease: Evidence from a multivariable two-sample Mendelian randomization study

genetics more details view paper
  • Downloaded 1,026 times
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    • Site-wide: 17,983
    • In genetics: 918
  • Year to date:
    • Site-wide: 88,334
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    • Site-wide: 87,973

Detecting and correcting for bias in Mendelian randomization analyses using gene-by-environment interactions

epidemiology more details view paper
  • Downloaded 1,010 times
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    • Site-wide: 18,460
    • In epidemiology: 1,058
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    • Site-wide: 68,006
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    • Site-wide: 60,759

Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: Findings from the Pregnancy and Childhood Epigenetics (PACE) consortium.

epidemiology more details view paper
  • Downloaded 1,007 times
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    • Site-wide: 18,540
    • In epidemiology: 1,062
  • Year to date:
    • Site-wide: 32,543
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    • Site-wide: 29,892

The effect of education on adult mortality, health, and income: triangulating across genetic and policy reforms

epidemiology more details view paper
  • Downloaded 1,005 times
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    • Site-wide: 18,609
    • In epidemiology: 1,065
  • Year to date:
    • Site-wide: 46,792
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    • Site-wide: 53,044

Robust inference in summary data Mendelian randomisation via the zero modal pleiotropy assumption

epidemiology more details view paper
  • Downloaded 966 times
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    • Site-wide: 19,681
    • In epidemiology: 1,112
  • Year to date:
    • Site-wide: 56,183
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    • Site-wide: 94,883

An epigenome-wide association study of educational attainment (n = 10,767)

genetics more details view paper
  • Downloaded 965 times
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    • Site-wide: 19,693
    • In genetics: 993
  • Year to date:
    • Site-wide: 60,083
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    • Site-wide: 118,664

Causal inference in cancer epidemiology: what is the role of Mendelian randomization?

epidemiology more details view paper
  • Downloaded 962 times
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    • Site-wide: 19,795
    • In epidemiology: 1,115
  • Year to date:
    • Site-wide: 60,942
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    • Site-wide: 117,793

Investigating the role of insulin in increased adiposity: Bi-directional Mendelian randomization study

epidemiology more details view paper
  • Downloaded 935 times
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    • Site-wide: 20,625
    • In epidemiology: 1,142
  • Year to date:
    • Site-wide: 51,604
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    • Site-wide: 82,151

Can education be personalised using pupils’ genetic data?

genetics more details view paper
  • Downloaded 921 times
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    • Site-wide: 21,069
    • In genetics: 1,055
  • Year to date:
    • Site-wide: 91,435
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    • Site-wide: 65,370

Apolipoprotein B underlies the causal relationship of circulating blood lipids with coronary heart disease

cardiovascular medicine more details view paper
  • Downloaded 884 times
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    • Site-wide: 22,392
    • In cardiovascular medicine: 31
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Imprinted loci may be more widespread in humans than previously appreciated and enable limited assignment of parental allelic transmissions in unrelated individuals

genomics more details view paper
  • Downloaded 863 times
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    • Site-wide: 23,151
    • In genomics: 2,272
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    • Site-wide: 32,676
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    • Site-wide: 79,457

Improving the visualisation, interpretation and analysis of two-sample summary data Mendelian randomization via the radial plot and radial regression

epidemiology more details view paper
  • Downloaded 834 times
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    • Site-wide: 24,318
    • In epidemiology: 1,277
  • Year to date:
    • Site-wide: 120,526
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    • Site-wide: 117,045

The causes and consequences of Alzheimer's disease: A Mendelian randomization analysis

genetic and genomic medicine more details view paper
  • Downloaded 821 times
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    • Site-wide: 24,818
    • In genetic and genomic medicine: 68
  • Year to date:
    • Site-wide: 5,402
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    • Site-wide: 24,062

Genetic Epidemiology And Mendelian Randomization For Informing Disease Therapeutics: Conceptual And Methodological Challenges

genetics more details view paper
  • Downloaded 782 times
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    • Site-wide: 26,597
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    • Site-wide: 108,412
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    • Site-wide: 116,285

Genetic Association Study of Childhood Aggression across raters, instruments and age

genomics more details view paper
  • Downloaded 772 times
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    • Site-wide: 27,052
    • In genomics: 2,556
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    • Site-wide: 32,144
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    • Site-wide: 36,465

The Causal Effect Of Educational Attainment On Alzheimer's Disease: A Two-Sample Mendelian Randomization Study

epidemiology more details view paper
  • Downloaded 758 times
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    • Site-wide: 27,786
    • In epidemiology: 1,413
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    • Site-wide: 42,613
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Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

genetics more details view paper
  • Downloaded 757 times
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    • Site-wide: 27,795
    • In genetics: 1,400
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MR-TRYX: A Mendelian randomization framework that exploits horizontal pleiotropy to infer novel causal pathways

bioinformatics more details view paper
  • Downloaded 757 times
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    • Site-wide: 27,832
    • In bioinformatics: 3,263
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    • Site-wide: 62,225

Integrating Mendelian randomization and multiple-trait colocalization to uncover cell-specific inflammatory drivers of autoimmune and atopic disease

genetics more details view paper
  • Downloaded 728 times
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    • Site-wide: 29,333
    • In genetics: 1,474
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    • Site-wide: 69,142
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    • Site-wide: 99,657

Examining the genetic influences of educational attainment and the validity of value-added measures of progress

genetics more details view paper
  • Downloaded 727 times
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    • Site-wide: 29,382
    • In genetics: 1,476
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    • Site-wide: 112,259
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Disentangling genetically confounded polygenic associations between Attention-Deficit/Hyperactivity Disorder, literacy and language

genetics more details view paper
  • Downloaded 716 times
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    • Site-wide: 30,040
    • In genetics: 1,511
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    • Site-wide: 48,925
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    • Site-wide: 113,085

Using genetics to examine a general liability to childhood psychopathology

genetics more details view paper
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    • Site-wide: 30,419
    • In genetics: 1,529
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    • Site-wide: 75,556
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Educational attainment impacts drinking behaviors and risk for alcohol dependence: results from a two-sample Mendelian randomization study with ~780 000 participants

epidemiology more details view paper
  • Downloaded 704 times
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    • Site-wide: 30,741
    • In epidemiology: 1,518
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    • Site-wide: 66,714
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    • Site-wide: 36,515

Trans-ethnic genome-wide association study provides insight into effector genes and molecular mechanisms for kidney function and highlights a causal effect on kidney-specific disease aetiologies

genetics more details view paper
  • Downloaded 703 times
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    • Site-wide: 30,790
    • In genetics: 1,549
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    • Site-wide: 87,581

Can the impact of childhood adiposity on disease risk be reversed? A Mendelian randomization study

epidemiology more details view paper
  • Downloaded 702 times
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    • Site-wide: 30,824
    • In epidemiology: 1,523
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    • Site-wide: 76,967
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Causal Inference for Heritable Phenotypic Risk Factors Using Heterogeneous Genetic Instruments

genetics more details view paper
  • Downloaded 689 times
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    • Site-wide: 31,595
    • In genetics: 1,586
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    • Site-wide: 10,977
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    • Site-wide: 4,778

Investigating causality between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization

genetics more details view paper
  • Downloaded 671 times
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    • Site-wide: 32,810
    • In genetics: 1,642
  • Year to date:
    • Site-wide: 74,550
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    • Site-wide: 74,687

Prioritizing putative influential genes in early life cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization

genetics more details view paper
  • Downloaded 667 times
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    • Site-wide: 33,059
    • In genetics: 1,648
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    • Site-wide: 93,212
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The molecular genetics of participation in the Avon Longitudinal Study of Parents and Children

genetics more details view paper
  • Downloaded 658 times
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Distinct Blood DNA Methylation Profiles In Subtypes Of Orofacial Cleft

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Evidence that low socioeconomic position accentuates genetic susceptibility to obesity

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Orienting The Causal Relationship Between Imprecisely Measured Traits Using Genetic Instruments

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Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment

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Education and coronary heart disease: a Mendelian randomization study

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Investigating the longitudinal consistency and genetic architecture of non-cognitive skills, and their relation to educational attainment

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Assessing the causal role of body mass index on cardiovascular health in young adults: Mendelian randomization and recall-by-genotype analyses

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Appraising the causal relevance of DNA methylation for risk of lung cancer

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Genetic architecture of early childhood growth phenotypes gives insights into their link with later obesity

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Detecting heterogeneity of intervention effects using analysis and meta-analysis of differences in variance between arms of a trial

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Disentangling causal relationships between inflammatory markers and depression: a bidirectional Mendelian randomization analysis

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Y chromosome and mitochondrial DNA haplogroups across behavioural traits in children from the general population

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Early metabolic features of genetic liability to type 2 diabetes: cohort study with repeated metabolomics across early life

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Genetic predictors of participation in optional components of UK Biobank

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Association of pre-pregnancy body mass index with future offspring metabolic profile: findings from three independent European birth cohorts

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Slope-Hunter: A robust method for index-event bias correction in genome-wide association studies of subsequent traits

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Is disrupted sleep a risk factor for Alzheimers disease? Evidence from a two-sample Mendelian randomization analysis

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Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

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Mendelian randomisation analysis of the effect of educational attainment and cognitive ability on smoking behaviour

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Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

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Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

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Metabolic signatures of birth weight in 18288 adolescents and adults

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Conditioning on a collider may induce spurious associations: Do the results of Gale et al. (2017) support a protective effect of neuroticism in population sub-groups?

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Cigarette smoking and personality: Investigating causality using Mendelian randomization

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Investigating causality in associations between education and smoking: A two-sample Mendelian randomization study

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The Parkinsons Disease Mendelian Randomization Research Portal

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What explains the effect of education on cardiovascular disease? Applying Mendelian randomization to identify the consequences of education inequality

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The median and the mode as robust meta-analysis methods in the presence of small study effects

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Evaluating the effects of alcohol and tobacco use on cardiovascular disease using multivariable Mendelian randomization

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Mendelian Randomization analysis reveals a causal influence of circulating sclerostin levels on bone mineral density and fractures

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A cross-disorder MR-pheWAS of 5 major psychiatric disorders in UK Biobank

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Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology

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The causal effect of adiposity on hospital costs: Mendelian Randomization analysis of over 300,000 individuals from the UK Biobank

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Systematic evaluation of the causal relationship between DNA methylation and C-reactive protein

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Genetic liability for schizophrenia and childhood psychopathology in the general population

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Epigenetic regulation of PAR4-related platelet activation: mechanistic links between environmental exposure and cardiovascular disease

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Evaluating causal associations between previously reported risk factors and epithelial ovarian cancer: a Mendelian randomization analysis

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Genetic liability to schizophrenia is associated with exposure to traumatic events in childhood

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PCSK9 genetic variants, life-long lowering of LDL-cholesterol and cognition: a large-scale Mendelian randomization study

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The effect of body mass index on smoking behaviour and nicotine metabolism: a Mendelian randomization study

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Association Between Genetically Elevated Levels Of Inflammatory Biomarkers And Risk Of Schizophrenia: A Two-Sample Mendelian Randomisation Study

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Schizophrenia risk and reproductive success: A Mendelian randomization study.

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Investigating the combined association of BMI and alcohol consumption on liver disease and biomarkers: a Mendelian randomization study of over 90 000 adults from the Copenhagen General Population Study

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Is genetic liability to ADHD and ASD causally linked to educational attainment?

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MR-pheWAS with stratification and interaction: Searching for the causal effects of smoking heaviness identified an effect on facial aging

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Circulating selenium and prostate cancer risk: a Mendelian randomization analysis

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CETP inhibition and ADCY9 genotype: evidence of a qualitative pharmacogenetic interaction in cardiovascular disease?

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Trans-ethnic Mendelian randomization study reveals causal relationships between cardio-metabolic factors and chronic kidney disease

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The association between adiposity and inpatient hospital costs in the UK Biobank cohort

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Examining the effect of smoking on suicidal ideation and attempts: A Mendelian randomisation study

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The MRC IEU OpenGWAS data infrastructure

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Testing the causal effects between subjective wellbeing and physical health using Mendelian randomisation

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Identifying novel subtypes of irritability using a developmental genetic approach

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Partitioning Phenotypic Variance Due To Parent-Of-Origin Effects Using Genomic Relatedness Matrices

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Lipoprotein Signatures of Cholesteryl Ester Transfer Protein and HMG-CoA Reductase Inhibition

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The effect of plasma lipids and lipid lowering interventions on bone mineral density: a Mendelian randomization study

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The use of negative control outcomes in Mendelian Randomisation to detect potential population stratification or selection bias.

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A rare SMAD9 mutation identifies the BMP signalling pathway as a potential osteoanabolic target

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Assortative mating and within-spouse pair comparisons

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DNA methylation mediates genetic liability to non-syndromic cleft lip/palate

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Paternal body mass index and offspring DNA methylation: findings from the PACE consortium

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Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study

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Sex differences in cardiometabolic traits at four life stages: cohort study with repeated metabolomics

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The Multivariate Genome-wide Architecture of Interrelated Literacy, Language and Working Memory Skills Reveals Distinct Etiologies

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Unhealthy Behaviours and Parkinsons Disease: A Mendelian Randomisation Study

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Epigenetic biomarkers of ageing are predictive of mortality risk in a longitudinal clinical cohort of individuals diagnosed with oropharyngeal cancer.

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Effects of apolipoprotein B on the lifespan and risks of major disease including type 2 diabetes: a Mendelian randomization analysis using outcomes in first-degree relatives

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A robust mean and variance test with application to high-dimensional phenotypes

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Do maternal intrauterine environmental influences that lower offspring birthweight causally increase offspring cardiometabolic risk factors in later life? A Mendelian randomization study of 45,849 genotyped parent offspring pairs in the HUNT study

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Proxy gene-by-environment Mendelian randomization study confirms a causal effect of maternal smoking on offspring birthweight, but little evidence of long-term influences on offspring health

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Biomarker de-Mendelization: principles, potentials and limitations of a strategy to improve biomarker prediction by reducing the component of variance explained by genotype

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Estimating the causal effect of genetic liability to prevalent disease on hospital costs using Mendelian Randomization

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Does Smoking Cause Lower Educational Attainment and General Cognitive Ability? Triangulation of causal evidence using multiple study designs

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Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization

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Mendelian randomization does not support serum calcium in prostate cancer risk

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The relationship between open angle glaucoma, optic disc morphology and Alzheimer's Disease: a Mendelian randomization study

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Educational inequalities in statin treatment for preventing cardiovascular disease: cross-sectional analysis of UK Biobank

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Interaction-based Mendelian randomization with measured and unmeasured gene-by-covariate interactions

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Developmental changes within the genetic architecture of social communication behaviour: A multivariate study of genetic variance in unrelated individuals

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Association between breastfeeding and DNA methylation over the life course: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC)

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Mendelian randomisation with coarsened exposures

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Exploring the causal effects of genetic liability to ADHD and Autism on Alzheimer's disease

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Evaluating the direct effects of childhood adiposity on adult systemic metabolism: A multivariable Mendelian randomization analysis

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The effect of smoking on multiple sclerosis: a mendelian randomization study

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Effects of adiposity on the human plasma proteome: Observational and Mendelian randomization estimates

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Examining the bidirectional association between emotion recognition and ASD symptoms using observational and genetic analyses

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The role of school enjoyment in the association between externalising and depressive symptoms and academic attainment: findings from a UK prospective cohort study

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Evaluating the effects of cardiometabolic exposures on circulating proteins which may contribute to SARS-CoV-2 severity

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Using human genetics to understand the causes and consequences of circulating cardiac troponin I in the general population

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Association of genetic liability to smoking initiation with e-cigarette use in young adults.

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The role of the metabolic profile in mediating the relationship between body mass index and left ventricular mass in adolescents: analysis of a prospective cohort study

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A phenome-wide multi-directional Mendelian randomization analysis of atrial fibrillation

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Examining the possible causal relationship between Lung Function, COPD and Alzheimers Disease. A Mendelian Randomization Study

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Body muscle gain and markers of cardiovascular disease susceptibility in young adulthood: prospective cohort study

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Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: a Mendelian randomization study

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Interpreting Mendelian randomization estimates of the effects of categorical exposures such as disease status and educational attainment

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Epidemiology and Genetics of Preserved Ratio Impaired SpiroMetry (PRISm): An Analysis of UK Biobank

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Causal effects of circulating cytokine concentrations on risk of Alzheimers disease: A bidirectional two-sample Mendelian randomization study

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Cross-sectional association of blood pressure variability and night-time dipping with cardiac structure in adolescents

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Sex-specific associations of adiposity with cardiometabolic traits: multi-life-stage cohort study with repeat metabolomics

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