Author: George Davey Smith
- ORCiD: http://orcid.org/0000-0002-1407-8314
- Most recently observed institution: University of Bristol
Rankings
- All-time downloads: 210,485 (rank: 230 )
- Categories:
- bioinformatics: 2,315 (rank: 5,609 (tie) )
- cardiovascular medicine: 1,093 (rank: 319 (tie) )
- epidemiology: 129,696 (rank: 97 )
- evolutionary biology: 414 (rank: 14,400 (tie) )
- genetic and genomic medicine: 3,003 (rank: 206 (tie) )
- genetics: 66,377 (rank: 47 )
- genomics: 3,330 (rank: 6,818 )
- health economics: 279 (rank: 361 (tie) )
- neurology: 305 (rank: 2,505 (tie) )
- neuroscience: 500 (rank: 39,455 (tie) )
- ophthalmology: 253 (rank: 355 (tie) )
- pharmacology and toxicology: 1,051 (rank: 934 (tie) )
- psychiatry and clinical psychology: 440 (rank: 1,636 (tie) )
- respiratory medicine: 245 (rank: 1,704 )
- systems biology: 1,184 (rank: 3,289 )
Downloads per author, site-wide
Preprints
An Informatics Consult approach for generating clinical evidence for treatment decisions
health informatics more details view paperNo download data for this paper yet.
Puberty and sex-specific trajectories of systolic blood pressure: a prospective cohort study
epidemiology more details view paperNo download data for this paper yet.
Selection into shift work is influenced by educational attainment and body mass index: A Mendelian randomization study
epidemiology more details view paper- Downloaded 61,419 times
- Download rankings, all-time:
- Site-wide: 78
- In epidemiology: 17
- Year to date:
- Site-wide: 85,629
- Since beginning of last month:
- Site-wide: 66
Collider bias undermines our understanding of COVID-19 disease risk and severity
epidemiology more details view paper- Downloaded 11,501 times
- Download rankings, all-time:
- Site-wide: 576
- In epidemiology: 86
- Year to date:
- Site-wide: 2,960
- Since beginning of last month:
- Site-wide: 1,594
A reference panel of 64,976 haplotypes for genotype imputation
genetics more details view paper- Downloaded 4,562 times
- Download rankings, all-time:
- Site-wide: 1,988
- In genetics: 80
- Year to date:
- Site-wide: 104,423
- Since beginning of last month:
- Site-wide: 60,320
MR-Base: a platform for systematic causal inference across the phenome using billions of genetic associations
epidemiology more details view paper- Downloaded 3,919 times
- Download rankings, all-time:
- Site-wide: 2,476
- In epidemiology: 250
- Year to date:
- Site-wide: 39,320
- Since beginning of last month:
- Site-wide: 17,504
Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases
genetics more details view paper- Downloaded 3,634 times
- Download rankings, all-time:
- Site-wide: 2,757
- In genetics: 111
- Year to date:
- Site-wide: 15,181
- Since beginning of last month:
- Site-wide: 10,772
PHESANT: a tool for performing automated phenome scans in UK Biobank
epidemiology more details view paper- Downloaded 3,359 times
- Download rankings, all-time:
- Site-wide: 3,111
- In epidemiology: 293
- Year to date:
- Site-wide: 9,925
- Since beginning of last month:
- Site-wide: 20,065
Automating Mendelian randomization through machine learning to construct a putative causal map of the human phenome
epidemiology more details view paper- Downloaded 3,261 times
- Download rankings, all-time:
- Site-wide: 3,254
- In epidemiology: 308
- Year to date:
- Site-wide: 22,409
- Since beginning of last month:
- Site-wide: 12,203
Collider Scope: When selection bias can substantially influence observed associations
epidemiology more details view paper- Downloaded 2,591 times
- Download rankings, all-time:
- Site-wide: 4,515
- In epidemiology: 388
- Year to date:
- Site-wide: 21,665
- Since beginning of last month:
- Site-wide: 44,825
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
genetics more details view paper- Downloaded 2,489 times
- Download rankings, all-time:
- Site-wide: 4,780
- In genetics: 231
- Year to date:
- Site-wide: 91,855
- Since beginning of last month:
- Site-wide: 94,842
Genome-wide association study identifies 48 common genetic variants associated with handedness
genetics more details view paper- Downloaded 2,476 times
- Download rankings, all-time:
- Site-wide: 4,820
- In genetics: 233
- Year to date:
- Site-wide: 18,572
- Since beginning of last month:
- Site-wide: 15,714
Mendelian randomization: a premature burial?
genetics more details view paper- Downloaded 2,405 times
- Download rankings, all-time:
- Site-wide: 5,056
- In genetics: 241
- Year to date:
- Site-wide: 15,387
- Since beginning of last month:
- Site-wide: 45,203
Why are education, socioeconomic position and intelligence genetically correlated?
genetics more details view paper- Downloaded 2,385 times
- Download rankings, all-time:
- Site-wide: 5,112
- In genetics: 247
- Year to date:
- Site-wide: 67,164
- Since beginning of last month:
- Site-wide: 30,561
Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders
genetics more details view paper- Downloaded 2,360 times
- Download rankings, all-time:
- Site-wide: 5,187
- In genetics: 251
- Year to date:
- Site-wide: 65,310
- Since beginning of last month:
- Site-wide: 82,904
Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis
epidemiology more details view paper- Downloaded 2,324 times
- Download rankings, all-time:
- Site-wide: 5,332
- In epidemiology: 439
- Year to date:
- Site-wide: 52,064
- Since beginning of last month:
- Site-wide: 102,253
Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases
genetics more details view paper- Downloaded 2,070 times
- Download rankings, all-time:
- Site-wide: 6,274
- In genetics: 315
- Year to date:
- Site-wide: 20,564
- Since beginning of last month:
- Site-wide: 23,507
Investigating causal relationships between sleep traits and risk of breast cancer: a Mendelian randomization study
epidemiology more details view paper- Downloaded 1,913 times
- Download rankings, all-time:
- Site-wide: 7,058
- In epidemiology: 540
- Year to date:
- Site-wide: 107,067
- Since beginning of last month:
- Site-wide: 96,123
An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome
genetics more details view paper- Downloaded 1,829 times
- Download rankings, all-time:
- Site-wide: 7,527
- In genetics: 374
- Year to date:
- Site-wide: 97,573
- Since beginning of last month:
- Site-wide: 56,103
Common genetic variants and health outcomes appear geographically structured in the UK Biobank sample: Old concerns returning and their implications.
genetics more details view paper- Downloaded 1,820 times
- Download rankings, all-time:
- Site-wide: 7,578
- In genetics: 376
- Year to date:
- Site-wide: 59,191
- Since beginning of last month:
- Site-wide: 80,287
Improving the accuracy of two-sample summary data Mendelian randomization: moving beyond the NOME assumption
epidemiology more details view paper- Downloaded 1,731 times
- Download rankings, all-time:
- Site-wide: 8,184
- In epidemiology: 598
- Year to date:
- Site-wide: 13,036
- Since beginning of last month:
- Site-wide: 47,663
Genomic analysis of diet composition finds novel loci and associations with health and lifestyle
genetics more details view paper- Downloaded 1,719 times
- Download rankings, all-time:
- Site-wide: 8,275
- In genetics: 417
- Year to date:
- Site-wide: 112,282
- Since beginning of last month:
- Site-wide: 71,207
Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide
genetics more details view paper- Downloaded 1,698 times
- Download rankings, all-time:
- Site-wide: 8,435
- In genetics: 425
- Year to date:
- Site-wide: 54,587
- Since beginning of last month:
- Site-wide: 59,742
Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism
genetics more details view paper- Downloaded 1,684 times
- Download rankings, all-time:
- Site-wide: 8,560
- In genetics: 435
- Year to date:
- Site-wide: 106,575
- Since beginning of last month:
- Site-wide: 63,504
Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population
genetics more details view paper- Downloaded 1,657 times
- Download rankings, all-time:
- Site-wide: 8,781
- In genetics: 446
- Year to date:
- Site-wide: 113,026
- Since beginning of last month:
- Site-wide: 100,761
A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome
genetics more details view paper- Downloaded 1,619 times
- Download rankings, all-time:
- Site-wide: 9,110
- In genetics: 464
- Year to date:
- Site-wide: 39,533
- Since beginning of last month:
- Site-wide: 119,680
Mendelian randomisation for mediation analysis: current methods and challenges for implementation
genetics more details view paper- Downloaded 1,569 times
- Download rankings, all-time:
- Site-wide: 9,532
- In genetics: 488
- Year to date:
- Site-wide: 3,378
- Since beginning of last month:
- Site-wide: 6,402
An examination of multivariable Mendelian randomization in the single sample and two-sample summary data settings.
epidemiology more details view paper- Downloaded 1,507 times
- Download rankings, all-time:
- Site-wide: 10,108
- In epidemiology: 700
- Year to date:
- Site-wide: 23,636
- Since beginning of last month:
- Site-wide: 44,859
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
genetics more details view paper- Downloaded 1,392 times
- Download rankings, all-time:
- Site-wide: 11,382
- In genetics: 582
- Year to date:
- Site-wide: 85,846
- Since beginning of last month:
- Site-wide: 61,479
The Causal Effects of Education on Health, Mortality, Cognition, Well-being, and Income in the UK Biobank
epidemiology more details view paper- Downloaded 1,384 times
- Download rankings, all-time:
- Site-wide: 11,477
- In epidemiology: 756
- Year to date:
- Site-wide: 35,652
- Since beginning of last month:
- Site-wide: 83,622
Cigarette smoking increases coffee consumption: findings from a Mendelian randomisation analysis
genetics more details view paper- Downloaded 1,367 times
- Download rankings, all-time:
- Site-wide: 11,683
- In genetics: 602
- Year to date:
- Site-wide: 32,909
- Since beginning of last month:
- Site-wide: 24,743
Do early life non-cognitive skills matter? A systematic review and meta-analysis of early life effects on academic achievement, psychosocial, language and cognitive, and health outcomes
epidemiology more details view paper- Downloaded 1,325 times
- Download rankings, all-time:
- Site-wide: 12,252
- In epidemiology: 801
- Year to date:
- Site-wide: 99,229
- Since beginning of last month:
- Site-wide: 68,378
Selection bias in instrumental variable analyses
epidemiology more details view paper- Downloaded 1,311 times
- Download rankings, all-time:
- Site-wide: 12,447
- In epidemiology: 813
- Year to date:
- Site-wide: 11,935
- Since beginning of last month:
- Site-wide: 25,722
The genetic architecture of osteoarthritis: insights from UK Biobank
genetics more details view paper- Downloaded 1,306 times
- Download rankings, all-time:
- Site-wide: 12,519
- In genetics: 639
- Year to date:
- Site-wide: 119,909
- Since beginning of last month:
- Site-wide: 58,810
Meffil: efficient normalisation and analysis of very large DNA methylation samples
bioinformatics more details view paper- Downloaded 1,269 times
- Download rankings, all-time:
- Site-wide: 13,072
- In bioinformatics: 1,639
- Year to date:
- Site-wide: 56,067
- Since beginning of last month:
- Site-wide: 64,984
Systematic Mendelian randomization framework elucidates hundreds of genetic loci which may influence disease through changes in DNA methylation levels
genetics more details view paper- Downloaded 1,260 times
- Download rankings, all-time:
- Site-wide: 13,230
- In genetics: 688
- Year to date:
- Site-wide: 97,773
- Since beginning of last month:
- Site-wide: 111,215
Causal epigenome-wide association study identifies CpG sites that influence cardiovascular disease risk
epidemiology more details view paper- Downloaded 1,196 times
- Download rankings, all-time:
- Site-wide: 14,292
- In epidemiology: 882
- Year to date:
- Site-wide: 50,552
- Since beginning of last month:
- Site-wide: 117,564
Alcohol consumption and mate choice in UK Biobank: comparing observational and Mendelian randomization estimates
genetics more details view paper- Downloaded 1,159 times
- Download rankings, all-time:
- Site-wide: 14,978
- In genetics: 775
- Year to date:
- Site-wide: 53,889
- Since beginning of last month:
- Site-wide: 48,328
Multi-omics study revealing tissue-dependent putative mechanisms of SARS-CoV-2 drug targets on viral infections and complex diseases
genetic and genomic medicine more details view paper- Downloaded 1,130 times
- Download rankings, all-time:
- Site-wide: 15,545
- In genetic and genomic medicine: 45
- Year to date:
- Site-wide: 19,594
- Since beginning of last month:
- Site-wide: 18,367
Narrow-sense heritability estimation of complex traits using identity-by-descent information.
genetics more details view paper- Downloaded 1,112 times
- Download rankings, all-time:
- Site-wide: 15,954
- In genetics: 823
- Year to date:
- Site-wide: 71,841
- Since beginning of last month:
- Site-wide: 69,447
Bayesian network analysis incorporating genetic anchors complements conventional Mendelian randomization approaches for exploratory analysis of causal relationships in complex data
genetics more details view paper- Downloaded 1,101 times
- Download rankings, all-time:
- Site-wide: 16,207
- In genetics: 837
- Year to date:
- Site-wide: 24,401
- Since beginning of last month:
- Site-wide: 91,409
Body mass index and mortality in UK Biobank: revised estimates using Mendelian randomization
epidemiology more details view paper- Downloaded 1,075 times
- Download rankings, all-time:
- Site-wide: 16,817
- In epidemiology: 993
- Year to date:
- Site-wide: 101,059
- Since beginning of last month:
- Site-wide: 88,114
Mendelian randomization: a novel approach for the prediction of adverse drug events and drug repurposing opportunities
pharmacology and toxicology more details view paper- Downloaded 1,051 times
- Download rankings, all-time:
- Site-wide: 17,376
- In pharmacology and toxicology: 98
- Year to date:
- Site-wide: 58,635
- Since beginning of last month:
- Site-wide: 99,364
Sex-associated autosomal DNA methylation differences are wide-spread and stable throughout childhood
epidemiology more details view paper- Downloaded 1,050 times
- Download rankings, all-time:
- Site-wide: 17,409
- In epidemiology: 1,023
- Year to date:
- Site-wide: 31,444
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- Site-wide: 22,590
Education, intelligence and Alzheimer's disease: Evidence from a multivariable two-sample Mendelian randomization study
genetics more details view paper- Downloaded 1,026 times
- Download rankings, all-time:
- Site-wide: 17,983
- In genetics: 918
- Year to date:
- Site-wide: 88,334
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- Site-wide: 87,973
Detecting and correcting for bias in Mendelian randomization analyses using gene-by-environment interactions
epidemiology more details view paper- Downloaded 1,010 times
- Download rankings, all-time:
- Site-wide: 18,460
- In epidemiology: 1,058
- Year to date:
- Site-wide: 68,006
- Since beginning of last month:
- Site-wide: 60,759
Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: Findings from the Pregnancy and Childhood Epigenetics (PACE) consortium.
epidemiology more details view paper- Downloaded 1,007 times
- Download rankings, all-time:
- Site-wide: 18,540
- In epidemiology: 1,062
- Year to date:
- Site-wide: 32,543
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- Site-wide: 29,892
The effect of education on adult mortality, health, and income: triangulating across genetic and policy reforms
epidemiology more details view paper- Downloaded 1,005 times
- Download rankings, all-time:
- Site-wide: 18,609
- In epidemiology: 1,065
- Year to date:
- Site-wide: 46,792
- Since beginning of last month:
- Site-wide: 53,044
Robust inference in summary data Mendelian randomisation via the zero modal pleiotropy assumption
epidemiology more details view paper- Downloaded 966 times
- Download rankings, all-time:
- Site-wide: 19,681
- In epidemiology: 1,112
- Year to date:
- Site-wide: 56,183
- Since beginning of last month:
- Site-wide: 94,883
An epigenome-wide association study of educational attainment (n = 10,767)
genetics more details view paper- Downloaded 965 times
- Download rankings, all-time:
- Site-wide: 19,693
- In genetics: 993
- Year to date:
- Site-wide: 60,083
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- Site-wide: 118,664
Causal inference in cancer epidemiology: what is the role of Mendelian randomization?
epidemiology more details view paper- Downloaded 962 times
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- Site-wide: 19,795
- In epidemiology: 1,115
- Year to date:
- Site-wide: 60,942
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- Site-wide: 117,793
Investigating the role of insulin in increased adiposity: Bi-directional Mendelian randomization study
epidemiology more details view paper- Downloaded 935 times
- Download rankings, all-time:
- Site-wide: 20,625
- In epidemiology: 1,142
- Year to date:
- Site-wide: 51,604
- Since beginning of last month:
- Site-wide: 82,151
Can education be personalised using pupils’ genetic data?
genetics more details view paper- Downloaded 921 times
- Download rankings, all-time:
- Site-wide: 21,069
- In genetics: 1,055
- Year to date:
- Site-wide: 91,435
- Since beginning of last month:
- Site-wide: 65,370
Apolipoprotein B underlies the causal relationship of circulating blood lipids with coronary heart disease
cardiovascular medicine more details view paper- Downloaded 884 times
- Download rankings, all-time:
- Site-wide: 22,392
- In cardiovascular medicine: 31
- Year to date:
- Site-wide: 44,020
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- Site-wide: 91,912
Imprinted loci may be more widespread in humans than previously appreciated and enable limited assignment of parental allelic transmissions in unrelated individuals
genomics more details view paper- Downloaded 863 times
- Download rankings, all-time:
- Site-wide: 23,151
- In genomics: 2,272
- Year to date:
- Site-wide: 32,676
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- Site-wide: 79,457
Improving the visualisation, interpretation and analysis of two-sample summary data Mendelian randomization via the radial plot and radial regression
epidemiology more details view paper- Downloaded 834 times
- Download rankings, all-time:
- Site-wide: 24,318
- In epidemiology: 1,277
- Year to date:
- Site-wide: 120,526
- Since beginning of last month:
- Site-wide: 117,045
The causes and consequences of Alzheimer's disease: A Mendelian randomization analysis
genetic and genomic medicine more details view paper- Downloaded 821 times
- Download rankings, all-time:
- Site-wide: 24,818
- In genetic and genomic medicine: 68
- Year to date:
- Site-wide: 5,402
- Since beginning of last month:
- Site-wide: 24,062
Genetic Epidemiology And Mendelian Randomization For Informing Disease Therapeutics: Conceptual And Methodological Challenges
genetics more details view paper- Downloaded 782 times
- Download rankings, all-time:
- Site-wide: 26,597
- In genetics: 1,342
- Year to date:
- Site-wide: 108,412
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- Site-wide: 116,285
Genetic Association Study of Childhood Aggression across raters, instruments and age
genomics more details view paper- Downloaded 772 times
- Download rankings, all-time:
- Site-wide: 27,052
- In genomics: 2,556
- Year to date:
- Site-wide: 32,144
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- Site-wide: 36,465
The Causal Effect Of Educational Attainment On Alzheimer's Disease: A Two-Sample Mendelian Randomization Study
epidemiology more details view paper- Downloaded 758 times
- Download rankings, all-time:
- Site-wide: 27,786
- In epidemiology: 1,413
- Year to date:
- Site-wide: 42,613
- Since beginning of last month:
- Site-wide: 79,784
Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways
genetics more details view paper- Downloaded 757 times
- Download rankings, all-time:
- Site-wide: 27,795
- In genetics: 1,400
- Year to date:
- Site-wide: 46,247
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- Site-wide: 74,226
MR-TRYX: A Mendelian randomization framework that exploits horizontal pleiotropy to infer novel causal pathways
bioinformatics more details view paper- Downloaded 757 times
- Download rankings, all-time:
- Site-wide: 27,832
- In bioinformatics: 3,263
- Year to date:
- Site-wide: 69,436
- Since beginning of last month:
- Site-wide: 62,225
Integrating Mendelian randomization and multiple-trait colocalization to uncover cell-specific inflammatory drivers of autoimmune and atopic disease
genetics more details view paper- Downloaded 728 times
- Download rankings, all-time:
- Site-wide: 29,333
- In genetics: 1,474
- Year to date:
- Site-wide: 69,142
- Since beginning of last month:
- Site-wide: 99,657
Examining the genetic influences of educational attainment and the validity of value-added measures of progress
genetics more details view paper- Downloaded 727 times
- Download rankings, all-time:
- Site-wide: 29,382
- In genetics: 1,476
- Year to date:
- Site-wide: 112,259
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- Site-wide: 110,440
Disentangling genetically confounded polygenic associations between Attention-Deficit/Hyperactivity Disorder, literacy and language
genetics more details view paper- Downloaded 716 times
- Download rankings, all-time:
- Site-wide: 30,040
- In genetics: 1,511
- Year to date:
- Site-wide: 48,925
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- Site-wide: 113,085
Using genetics to examine a general liability to childhood psychopathology
genetics more details view paper- Downloaded 709 times
- Download rankings, all-time:
- Site-wide: 30,419
- In genetics: 1,529
- Year to date:
- Site-wide: 75,556
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- Site-wide: 114,377
Educational attainment impacts drinking behaviors and risk for alcohol dependence: results from a two-sample Mendelian randomization study with ~780 000 participants
epidemiology more details view paper- Downloaded 704 times
- Download rankings, all-time:
- Site-wide: 30,741
- In epidemiology: 1,518
- Year to date:
- Site-wide: 66,714
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- Site-wide: 36,515
Trans-ethnic genome-wide association study provides insight into effector genes and molecular mechanisms for kidney function and highlights a causal effect on kidney-specific disease aetiologies
genetics more details view paper- Downloaded 703 times
- Download rankings, all-time:
- Site-wide: 30,790
- In genetics: 1,549
- Year to date:
- Site-wide: 96,437
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- Site-wide: 87,581
Can the impact of childhood adiposity on disease risk be reversed? A Mendelian randomization study
epidemiology more details view paper- Downloaded 702 times
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- Site-wide: 30,824
- In epidemiology: 1,523
- Year to date:
- Site-wide: 76,967
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- Site-wide: 104,418
Causal Inference for Heritable Phenotypic Risk Factors Using Heterogeneous Genetic Instruments
genetics more details view paper- Downloaded 689 times
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- Site-wide: 31,595
- In genetics: 1,586
- Year to date:
- Site-wide: 10,977
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- Site-wide: 4,778
Investigating causality between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization
genetics more details view paper- Downloaded 671 times
- Download rankings, all-time:
- Site-wide: 32,810
- In genetics: 1,642
- Year to date:
- Site-wide: 74,550
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- Site-wide: 74,687
Prioritizing putative influential genes in early life cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization
genetics more details view paper- Downloaded 667 times
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- Site-wide: 33,059
- In genetics: 1,648
- Year to date:
- Site-wide: 93,212
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- Site-wide: 107,778
The molecular genetics of participation in the Avon Longitudinal Study of Parents and Children
genetics more details view paper- Downloaded 658 times
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- Site-wide: 33,649
- In genetics: 1,676
- Year to date:
- Site-wide: 120,373
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- Site-wide: 108,498
Distinct Blood DNA Methylation Profiles In Subtypes Of Orofacial Cleft
epidemiology more details view paper- Downloaded 655 times
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- Site-wide: 33,837
- In epidemiology: 1,615
- Year to date:
- Site-wide: 98,331
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- Site-wide: 87,395
Evidence that low socioeconomic position accentuates genetic susceptibility to obesity
genetics more details view paper- Downloaded 652 times
- Download rankings, all-time:
- Site-wide: 34,055
- In genetics: 1,696
- Year to date:
- Site-wide: 94,772
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- Site-wide: 103,990
Orienting The Causal Relationship Between Imprecisely Measured Traits Using Genetic Instruments
systems biology more details view paper- Downloaded 644 times
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- Site-wide: 34,676
- In systems biology: 812
- Year to date:
- Site-wide: 76,290
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- Site-wide: 116,265
Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment
epidemiology more details view paper- Downloaded 643 times
- Download rankings, all-time:
- Site-wide: 34,720
- In epidemiology: 1,639
- Year to date:
- Site-wide: 94,834
- Since beginning of last month:
- Site-wide: 108,036
Education and coronary heart disease: a Mendelian randomization study
epidemiology more details view paper- Downloaded 634 times
- Download rankings, all-time:
- Site-wide: 35,340
- In epidemiology: 1,663
- Year to date:
- Site-wide: 100,439
- Since beginning of last month:
- Site-wide: 99,283
Investigating the longitudinal consistency and genetic architecture of non-cognitive skills, and their relation to educational attainment
genetics more details view paper- Downloaded 625 times
- Download rankings, all-time:
- Site-wide: 36,023
- In genetics: 1,790
- Year to date:
- Site-wide: 27,740
- Since beginning of last month:
- Site-wide: 46,029
Assessing the causal role of body mass index on cardiovascular health in young adults: Mendelian randomization and recall-by-genotype analyses
epidemiology more details view paper- Downloaded 625 times
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Appraising the causal relevance of DNA methylation for risk of lung cancer
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Genetic architecture of early childhood growth phenotypes gives insights into their link with later obesity
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Detecting heterogeneity of intervention effects using analysis and meta-analysis of differences in variance between arms of a trial
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Disentangling causal relationships between inflammatory markers and depression: a bidirectional Mendelian randomization analysis
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Y chromosome and mitochondrial DNA haplogroups across behavioural traits in children from the general population
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Early metabolic features of genetic liability to type 2 diabetes: cohort study with repeated metabolomics across early life
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Genetic predictors of participation in optional components of UK Biobank
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Association of pre-pregnancy body mass index with future offspring metabolic profile: findings from three independent European birth cohorts
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Slope-Hunter: A robust method for index-event bias correction in genome-wide association studies of subsequent traits
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Is disrupted sleep a risk factor for Alzheimers disease? Evidence from a two-sample Mendelian randomization analysis
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Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility
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Mendelian randomisation analysis of the effect of educational attainment and cognitive ability on smoking behaviour
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Genomic and phenomic insights from an atlas of genetic effects on DNA methylation
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Low-frequency variation in TP53 has large effects on head circumference and intracranial volume
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Metabolic signatures of birth weight in 18288 adolescents and adults
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Conditioning on a collider may induce spurious associations: Do the results of Gale et al. (2017) support a protective effect of neuroticism in population sub-groups?
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Cigarette smoking and personality: Investigating causality using Mendelian randomization
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Investigating causality in associations between education and smoking: A two-sample Mendelian randomization study
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The Parkinsons Disease Mendelian Randomization Research Portal
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What explains the effect of education on cardiovascular disease? Applying Mendelian randomization to identify the consequences of education inequality
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The median and the mode as robust meta-analysis methods in the presence of small study effects
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Evaluating the effects of alcohol and tobacco use on cardiovascular disease using multivariable Mendelian randomization
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Mendelian Randomization analysis reveals a causal influence of circulating sclerostin levels on bone mineral density and fractures
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A cross-disorder MR-pheWAS of 5 major psychiatric disorders in UK Biobank
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Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology
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The causal effect of adiposity on hospital costs: Mendelian Randomization analysis of over 300,000 individuals from the UK Biobank
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Systematic evaluation of the causal relationship between DNA methylation and C-reactive protein
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Genetic liability for schizophrenia and childhood psychopathology in the general population
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Epigenetic regulation of PAR4-related platelet activation: mechanistic links between environmental exposure and cardiovascular disease
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Evaluating causal associations between previously reported risk factors and epithelial ovarian cancer: a Mendelian randomization analysis
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Genetic liability to schizophrenia is associated with exposure to traumatic events in childhood
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PCSK9 genetic variants, life-long lowering of LDL-cholesterol and cognition: a large-scale Mendelian randomization study
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The effect of body mass index on smoking behaviour and nicotine metabolism: a Mendelian randomization study
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Association Between Genetically Elevated Levels Of Inflammatory Biomarkers And Risk Of Schizophrenia: A Two-Sample Mendelian Randomisation Study
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Schizophrenia risk and reproductive success: A Mendelian randomization study.
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Investigating the combined association of BMI and alcohol consumption on liver disease and biomarkers: a Mendelian randomization study of over 90 000 adults from the Copenhagen General Population Study
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Is genetic liability to ADHD and ASD causally linked to educational attainment?
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MR-pheWAS with stratification and interaction: Searching for the causal effects of smoking heaviness identified an effect on facial aging
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Circulating selenium and prostate cancer risk: a Mendelian randomization analysis
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CETP inhibition and ADCY9 genotype: evidence of a qualitative pharmacogenetic interaction in cardiovascular disease?
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Trans-ethnic Mendelian randomization study reveals causal relationships between cardio-metabolic factors and chronic kidney disease
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The association between adiposity and inpatient hospital costs in the UK Biobank cohort
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Examining the effect of smoking on suicidal ideation and attempts: A Mendelian randomisation study
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The MRC IEU OpenGWAS data infrastructure
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Testing the causal effects between subjective wellbeing and physical health using Mendelian randomisation
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Identifying novel subtypes of irritability using a developmental genetic approach
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Partitioning Phenotypic Variance Due To Parent-Of-Origin Effects Using Genomic Relatedness Matrices
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Lipoprotein Signatures of Cholesteryl Ester Transfer Protein and HMG-CoA Reductase Inhibition
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The effect of plasma lipids and lipid lowering interventions on bone mineral density: a Mendelian randomization study
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The use of negative control outcomes in Mendelian Randomisation to detect potential population stratification or selection bias.
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A rare SMAD9 mutation identifies the BMP signalling pathway as a potential osteoanabolic target
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Assortative mating and within-spouse pair comparisons
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DNA methylation mediates genetic liability to non-syndromic cleft lip/palate
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Paternal body mass index and offspring DNA methylation: findings from the PACE consortium
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Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study
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Sex differences in cardiometabolic traits at four life stages: cohort study with repeated metabolomics
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The Multivariate Genome-wide Architecture of Interrelated Literacy, Language and Working Memory Skills Reveals Distinct Etiologies
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Unhealthy Behaviours and Parkinsons Disease: A Mendelian Randomisation Study
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Epigenetic biomarkers of ageing are predictive of mortality risk in a longitudinal clinical cohort of individuals diagnosed with oropharyngeal cancer.
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Effects of apolipoprotein B on the lifespan and risks of major disease including type 2 diabetes: a Mendelian randomization analysis using outcomes in first-degree relatives
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A robust mean and variance test with application to high-dimensional phenotypes
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Do maternal intrauterine environmental influences that lower offspring birthweight causally increase offspring cardiometabolic risk factors in later life? A Mendelian randomization study of 45,849 genotyped parent offspring pairs in the HUNT study
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Proxy gene-by-environment Mendelian randomization study confirms a causal effect of maternal smoking on offspring birthweight, but little evidence of long-term influences on offspring health
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Biomarker de-Mendelization: principles, potentials and limitations of a strategy to improve biomarker prediction by reducing the component of variance explained by genotype
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Estimating the causal effect of genetic liability to prevalent disease on hospital costs using Mendelian Randomization
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Does Smoking Cause Lower Educational Attainment and General Cognitive Ability? Triangulation of causal evidence using multiple study designs
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Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization
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Mendelian randomization does not support serum calcium in prostate cancer risk
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The relationship between open angle glaucoma, optic disc morphology and Alzheimer's Disease: a Mendelian randomization study
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Educational inequalities in statin treatment for preventing cardiovascular disease: cross-sectional analysis of UK Biobank
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Interaction-based Mendelian randomization with measured and unmeasured gene-by-covariate interactions
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Developmental changes within the genetic architecture of social communication behaviour: A multivariate study of genetic variance in unrelated individuals
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Association between breastfeeding and DNA methylation over the life course: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC)
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Mendelian randomisation with coarsened exposures
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Exploring the causal effects of genetic liability to ADHD and Autism on Alzheimer's disease
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Evaluating the direct effects of childhood adiposity on adult systemic metabolism: A multivariable Mendelian randomization analysis
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The effect of smoking on multiple sclerosis: a mendelian randomization study
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Effects of adiposity on the human plasma proteome: Observational and Mendelian randomization estimates
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Examining the bidirectional association between emotion recognition and ASD symptoms using observational and genetic analyses
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The role of school enjoyment in the association between externalising and depressive symptoms and academic attainment: findings from a UK prospective cohort study
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Evaluating the effects of cardiometabolic exposures on circulating proteins which may contribute to SARS-CoV-2 severity
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Using human genetics to understand the causes and consequences of circulating cardiac troponin I in the general population
epidemiology more details view paper- Downloaded 175 times
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Association of genetic liability to smoking initiation with e-cigarette use in young adults.
epidemiology more details view paper- Downloaded 173 times
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The role of the metabolic profile in mediating the relationship between body mass index and left ventricular mass in adolescents: analysis of a prospective cohort study
epidemiology more details view paper- Downloaded 172 times
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A phenome-wide multi-directional Mendelian randomization analysis of atrial fibrillation
epidemiology more details view paper- Downloaded 164 times
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Examining the possible causal relationship between Lung Function, COPD and Alzheimers Disease. A Mendelian Randomization Study
respiratory medicine more details view paper- Downloaded 138 times
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Body muscle gain and markers of cardiovascular disease susceptibility in young adulthood: prospective cohort study
epidemiology more details view paper- Downloaded 129 times
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Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: a Mendelian randomization study
epidemiology more details view paper- Downloaded 126 times
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Interpreting Mendelian randomization estimates of the effects of categorical exposures such as disease status and educational attainment
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Epidemiology and Genetics of Preserved Ratio Impaired SpiroMetry (PRISm): An Analysis of UK Biobank
respiratory medicine more details view paper- Downloaded 107 times
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Causal effects of circulating cytokine concentrations on risk of Alzheimers disease: A bidirectional two-sample Mendelian randomization study
genetic and genomic medicine more details view paper- Downloaded 104 times
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Cross-sectional association of blood pressure variability and night-time dipping with cardiac structure in adolescents
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Sex-specific associations of adiposity with cardiometabolic traits: multi-life-stage cohort study with repeat metabolomics
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News
- 27 Nov 2020: The website and API now include results pulled from medRxiv as well as bioRxiv.
- 18 Dec 2019: We're pleased to announce PanLingua, a new tool that enables you to search for machine-translated bioRxiv preprints using more than 100 different languages.
- 21 May 2019: PLOS Biology has published a community page about Rxivist.org and its design.
- 10 May 2019: The paper analyzing the Rxivist dataset has been published at eLife.
- 1 Mar 2019: We now have summary statistics about bioRxiv downloads and submissions.
- 8 Feb 2019: Data from Altmetric is now available on the Rxivist details page for every preprint. Look for the "donut" under the download metrics.
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- 22 Jan 2019: Nature just published an article about Rxivist and our data.
- 13 Jan 2019: The Rxivist preprint is live!