Author: George Davey Smith
- ORCiD: http://orcid.org/0000-0002-1407-8314
- Most recently observed institution: University of Bristol
Rankings
- All-time downloads: 219,961 (rank: 227 )
- Categories:
- bioinformatics: 2,406 (rank: 5,751 (tie) )
- cardiovascular medicine: 1,154 (rank: 339 (tie) )
- epidemiology: 133,531 (rank: 96 )
- evolutionary biology: 427 (rank: 14,992 (tie) )
- genetic and genomic medicine: 3,566 (rank: 266 )
- genetics: 69,327 (rank: 46 )
- genomics: 3,631 (rank: 6,609 )
- health economics: 319 (rank: 411 (tie) )
- health informatics: 141 (rank: 2,835 (tie) )
- neurology: 1,027 (rank: 777 )
- neuroscience: 508 (rank: 42,599 (tie) )
- ophthalmology: 294 (rank: 368 (tie) )
- pharmacology and toxicology: 1,061 (rank: 1,023 (tie) )
- psychiatry and clinical psychology: 1,071 (rank: 911 )
- respiratory medicine: 292 (rank: 1,763 )
- systems biology: 1,206 (rank: 3,524 (tie) )
Downloads per author, site-wide
Preprints
Selection into shift work is influenced by educational attainment and body mass index: A Mendelian randomization study
epidemiology more details view paper- Downloaded 61,469 times
- Download rankings, all-time:
- Site-wide: 87
- In epidemiology: 20
- Year to date:
- Site-wide: 48,298
- Since beginning of last month:
- Site-wide: 34,102
Collider bias undermines our understanding of COVID-19 disease risk and severity
epidemiology more details view paper- Downloaded 11,992 times
- Download rankings, all-time:
- Site-wide: 623
- In epidemiology: 89
- Year to date:
- Site-wide: 2,339
- Since beginning of last month:
- Site-wide: 2,225
A reference panel of 64,976 haplotypes for genotype imputation
genetics more details view paper- Downloaded 4,588 times
- Download rankings, all-time:
- Site-wide: 2,245
- In genetics: 82
- Year to date:
- Site-wide: 79,874
- Since beginning of last month:
- Site-wide: 97,228
MR-Base: a platform for systematic causal inference across the phenome using billions of genetic associations
epidemiology more details view paper- Downloaded 4,025 times
- Download rankings, all-time:
- Site-wide: 2,702
- In epidemiology: 287
- Year to date:
- Site-wide: 21,428
- Since beginning of last month:
- Site-wide: 25,811
Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases
genetics more details view paper- Downloaded 3,834 times
- Download rankings, all-time:
- Site-wide: 2,909
- In genetics: 113
- Year to date:
- Site-wide: 9,258
- Since beginning of last month:
- Site-wide: 9,163
PHESANT: a tool for performing automated phenome scans in UK Biobank
epidemiology more details view paper- Downloaded 3,473 times
- Download rankings, all-time:
- Site-wide: 3,358
- In epidemiology: 331
- Year to date:
- Site-wide: 15,534
- Since beginning of last month:
- Site-wide: 12,823
Automating Mendelian randomization through machine learning to construct a putative causal map of the human phenome
epidemiology more details view paper- Downloaded 3,426 times
- Download rankings, all-time:
- Site-wide: 3,419
- In epidemiology: 335
- Year to date:
- Site-wide: 12,225
- Since beginning of last month:
- Site-wide: 15,597
Collider Scope: When selection bias can substantially influence observed associations
epidemiology more details view paper- Downloaded 2,653 times
- Download rankings, all-time:
- Site-wide: 4,933
- In epidemiology: 440
- Year to date:
- Site-wide: 32,039
- Since beginning of last month:
- Site-wide: 30,209
Genome-wide association study identifies 48 common genetic variants associated with handedness
genetics more details view paper- Downloaded 2,567 times
- Download rankings, all-time:
- Site-wide: 5,167
- In genetics: 235
- Year to date:
- Site-wide: 22,449
- Since beginning of last month:
- Site-wide: 26,966
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
genetics more details view paper- Downloaded 2,509 times
- Download rankings, all-time:
- Site-wide: 5,345
- In genetics: 245
- Year to date:
- Site-wide: 90,402
- Since beginning of last month:
- Site-wide: 89,367
Mendelian randomization: a premature burial?
genetics more details view paper- Downloaded 2,455 times
- Download rankings, all-time:
- Site-wide: 5,541
- In genetics: 257
- Year to date:
- Site-wide: 34,412
- Since beginning of last month:
- Site-wide: 49,273
Why are education, socioeconomic position and intelligence genetically correlated?
genetics more details view paper- Downloaded 2,435 times
- Download rankings, all-time:
- Site-wide: 5,609
- In genetics: 260
- Year to date:
- Site-wide: 45,576
- Since beginning of last month:
- Site-wide: 53,799
Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders
genetics more details view paper- Downloaded 2,377 times
- Download rankings, all-time:
- Site-wide: 5,794
- In genetics: 270
- Year to date:
- Site-wide: 90,371
- Since beginning of last month:
- Site-wide: 107,700
Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis
epidemiology more details view paper- Downloaded 2,341 times
- Download rankings, all-time:
- Site-wide: 5,934
- In epidemiology: 494
- Year to date:
- Site-wide: 86,399
- Since beginning of last month:
- Site-wide: 129,184
Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases
genetics more details view paper- Downloaded 2,168 times
- Download rankings, all-time:
- Site-wide: 6,620
- In genetics: 320
- Year to date:
- Site-wide: 21,387
- Since beginning of last month:
- Site-wide: 19,344
Investigating causal relationships between sleep traits and risk of breast cancer: a Mendelian randomization study
epidemiology more details view paper- Downloaded 1,930 times
- Download rankings, all-time:
- Site-wide: 7,873
- In epidemiology: 613
- Year to date:
- Site-wide: 103,413
- Since beginning of last month:
- Site-wide: 75,400
An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome
genetics more details view paper- Downloaded 1,877 times
- Download rankings, all-time:
- Site-wide: 8,228
- In genetics: 380
- Year to date:
- Site-wide: 50,396
- Since beginning of last month:
- Site-wide: 33,569
Common genetic variants and health outcomes appear geographically structured in the UK Biobank sample: Old concerns returning and their implications.
genetics more details view paper- Downloaded 1,856 times
- Download rankings, all-time:
- Site-wide: 8,364
- In genetics: 392
- Year to date:
- Site-wide: 57,751
- Since beginning of last month:
- Site-wide: 53,623
Improving the accuracy of two-sample summary data Mendelian randomization: moving beyond the NOME assumption
epidemiology more details view paper- Downloaded 1,825 times
- Download rankings, all-time:
- Site-wide: 8,587
- In epidemiology: 657
- Year to date:
- Site-wide: 20,189
- Since beginning of last month:
- Site-wide: 16,000
Mendelian randomisation for mediation analysis: current methods and challenges for implementation
genetics more details view paper- Downloaded 1,790 times
- Download rankings, all-time:
- Site-wide: 8,822
- In genetics: 416
- Year to date:
- Site-wide: 5,826
- Since beginning of last month:
- Site-wide: 5,686
Genomic analysis of diet composition finds novel loci and associations with health and lifestyle
genetics more details view paper- Downloaded 1,751 times
- Download rankings, all-time:
- Site-wide: 9,145
- In genetics: 437
- Year to date:
- Site-wide: 70,161
- Since beginning of last month:
- Site-wide: 60,850
Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide
genetics more details view paper- Downloaded 1,717 times
- Download rankings, all-time:
- Site-wide: 9,415
- In genetics: 450
- Year to date:
- Site-wide: 84,041
- Since beginning of last month:
- Site-wide: 89,315
Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism
genetics more details view paper- Downloaded 1,713 times
- Download rankings, all-time:
- Site-wide: 9,445
- In genetics: 453
- Year to date:
- Site-wide: 75,535
- Since beginning of last month:
- Site-wide: 80,623
Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population
genetics more details view paper- Downloaded 1,676 times
- Download rankings, all-time:
- Site-wide: 9,752
- In genetics: 465
- Year to date:
- Site-wide: 98,354
- Since beginning of last month:
- Site-wide: 107,619
A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome
genetics more details view paper- Downloaded 1,622 times
- Download rankings, all-time:
- Site-wide: 10,220
- In genetics: 492
- Year to date:
- Site-wide: 114,977
- Since beginning of last month:
- Site-wide: 130,910
An examination of multivariable Mendelian randomization in the single sample and two-sample summary data settings.
epidemiology more details view paper- Downloaded 1,547 times
- Download rankings, all-time:
- Site-wide: 10,965
- In epidemiology: 781
- Year to date:
- Site-wide: 44,514
- Since beginning of last month:
- Site-wide: 34,886
Cigarette smoking increases coffee consumption: findings from a Mendelian randomisation analysis
genetics more details view paper- Downloaded 1,417 times
- Download rankings, all-time:
- Site-wide: 12,480
- In genetics: 613
- Year to date:
- Site-wide: 40,914
- Since beginning of last month:
- Site-wide: 46,072
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
genetics more details view paper- Downloaded 1,413 times
- Download rankings, all-time:
- Site-wide: 12,529
- In genetics: 616
- Year to date:
- Site-wide: 87,649
- Since beginning of last month:
- Site-wide: 66,731
The Causal Effects of Education on Health, Mortality, Cognition, Well-being, and Income in the UK Biobank
epidemiology more details view paper- Downloaded 1,406 times
- Download rankings, all-time:
- Site-wide: 12,616
- In epidemiology: 851
- Year to date:
- Site-wide: 69,396
- Since beginning of last month:
- Site-wide: 78,937
Selection bias in instrumental variable analyses
epidemiology more details view paper- Downloaded 1,377 times
- Download rankings, all-time:
- Site-wide: 13,021
- In epidemiology: 875
- Year to date:
- Site-wide: 25,917
- Since beginning of last month:
- Site-wide: 28,057
Do early life non-cognitive skills matter? A systematic review and meta-analysis of early life effects on academic achievement, psychosocial, language and cognitive, and health outcomes
epidemiology more details view paper- Downloaded 1,341 times
- Download rankings, all-time:
- Site-wide: 13,547
- In epidemiology: 896
- Year to date:
- Site-wide: 103,666
- Since beginning of last month:
- Site-wide: 95,917
The genetic architecture of osteoarthritis: insights from UK Biobank
genetics more details view paper- Downloaded 1,338 times
- Download rankings, all-time:
- Site-wide: 13,610
- In genetics: 663
- Year to date:
- Site-wide: 72,149
- Since beginning of last month:
- Site-wide: 97,088
Meffil: efficient normalisation and analysis of very large DNA methylation samples
bioinformatics more details view paper- Downloaded 1,294 times
- Download rankings, all-time:
- Site-wide: 14,344
- In bioinformatics: 1,745
- Year to date:
- Site-wide: 71,907
- Since beginning of last month:
- Site-wide: 73,854
Systematic Mendelian randomization framework elucidates hundreds of genetic loci which may influence disease through changes in DNA methylation levels
genetics more details view paper- Downloaded 1,267 times
- Download rankings, all-time:
- Site-wide: 14,810
- In genetics: 733
- Year to date:
- Site-wide: 128,472
- Since beginning of last month:
- Site-wide: 130,908
Causal epigenome-wide association study identifies CpG sites that influence cardiovascular disease risk
epidemiology more details view paper- Downloaded 1,215 times
- Download rankings, all-time:
- Site-wide: 15,770
- In epidemiology: 1,004
- Year to date:
- Site-wide: 81,181
- Since beginning of last month:
- Site-wide: 98,846
Multi-omics study revealing tissue-dependent putative mechanisms of SARS-CoV-2 drug targets on viral infections and complex diseases
genetic and genomic medicine more details view paper- Downloaded 1,191 times
- Download rankings, all-time:
- Site-wide: 16,249
- In genetic and genomic medicine: 55
- Year to date:
- Site-wide: 31,614
- Since beginning of last month:
- Site-wide: 30,749
Alcohol consumption and mate choice in UK Biobank: comparing observational and Mendelian randomization estimates
genetics more details view paper- Downloaded 1,179 times
- Download rankings, all-time:
- Site-wide: 16,468
- In genetics: 804
- Year to date:
- Site-wide: 81,025
- Since beginning of last month:
- Site-wide: 88,349
Sex-associated autosomal DNA methylation differences are wide-spread and stable throughout childhood
epidemiology more details view paper- Downloaded 1,144 times
- Download rankings, all-time:
- Site-wide: 17,218
- In epidemiology: 1,070
- Year to date:
- Site-wide: 23,929
- Since beginning of last month:
- Site-wide: 24,783
Narrow-sense heritability estimation of complex traits using identity-by-descent information.
genetics more details view paper- Downloaded 1,138 times
- Download rankings, all-time:
- Site-wide: 17,352
- In genetics: 849
- Year to date:
- Site-wide: 74,527
- Since beginning of last month:
- Site-wide: 65,644
Bayesian network analysis incorporating genetic anchors complements conventional Mendelian randomization approaches for exploratory analysis of causal relationships in complex data
genetics more details view paper- Downloaded 1,126 times
- Download rankings, all-time:
- Site-wide: 17,638
- In genetics: 864
- Year to date:
- Site-wide: 58,173
- Since beginning of last month:
- Site-wide: 60,579
Body mass index and mortality in UK Biobank: revised estimates using Mendelian randomization
epidemiology more details view paper- Downloaded 1,103 times
- Download rankings, all-time:
- Site-wide: 18,178
- In epidemiology: 1,108
- Year to date:
- Site-wide: 75,765
- Since beginning of last month:
- Site-wide: 66,578
Mendelian randomization: a novel approach for the prediction of adverse drug events and drug repurposing opportunities
pharmacology and toxicology more details view paper- Downloaded 1,061 times
- Download rankings, all-time:
- Site-wide: 19,258
- In pharmacology and toxicology: 104
- Year to date:
- Site-wide: 106,155
- Since beginning of last month:
- Site-wide: 90,437
Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: Findings from the Pregnancy and Childhood Epigenetics (PACE) consortium.
epidemiology more details view paper- Downloaded 1,049 times
- Download rankings, all-time:
- Site-wide: 19,586
- In epidemiology: 1,166
- Year to date:
- Site-wide: 46,759
- Since beginning of last month:
- Site-wide: 33,217
Education, intelligence and Alzheimer's disease: Evidence from a multivariable two-sample Mendelian randomization study
genetics more details view paper- Downloaded 1,045 times
- Download rankings, all-time:
- Site-wide: 19,690
- In genetics: 951
- Year to date:
- Site-wide: 93,536
- Since beginning of last month:
- Site-wide: 90,699
Detecting and correcting for bias in Mendelian randomization analyses using gene-by-environment interactions
epidemiology more details view paper- Downloaded 1,035 times
- Download rankings, all-time:
- Site-wide: 19,967
- In epidemiology: 1,182
- Year to date:
- Site-wide: 75,719
- Since beginning of last month:
- Site-wide: 89,729
The effect of education on adult mortality, health, and income: triangulating across genetic and policy reforms
epidemiology more details view paper- Downloaded 1,028 times
- Download rankings, all-time:
- Site-wide: 20,177
- In epidemiology: 1,197
- Year to date:
- Site-wide: 72,410
- Since beginning of last month:
- Site-wide: 85,920
An epigenome-wide association study of educational attainment (n = 10,767)
genetics more details view paper- Downloaded 996 times
- Download rankings, all-time:
- Site-wide: 21,078
- In genetics: 1,012
- Year to date:
- Site-wide: 62,856
- Since beginning of last month:
- Site-wide: 63,046
Causal inference in cancer epidemiology: what is the role of Mendelian randomization?
epidemiology more details view paper- Downloaded 990 times
- Download rankings, all-time:
- Site-wide: 21,261
- In epidemiology: 1,235
- Year to date:
- Site-wide: 69,295
- Since beginning of last month:
- Site-wide: 72,403
Robust inference in summary data Mendelian randomisation via the zero modal pleiotropy assumption
epidemiology more details view paper- Downloaded 985 times
- Download rankings, all-time:
- Site-wide: 21,402
- In epidemiology: 1,240
- Year to date:
- Site-wide: 84,009
- Since beginning of last month:
- Site-wide: 74,778
Investigating the role of insulin in increased adiposity: Bi-directional Mendelian randomization study
epidemiology more details view paper- Downloaded 968 times
- Download rankings, all-time:
- Site-wide: 21,973
- In epidemiology: 1,263
- Year to date:
- Site-wide: 59,381
- Since beginning of last month:
- Site-wide: 53,672
The causes and consequences of Alzheimer's disease: A Mendelian randomization analysis
genetic and genomic medicine more details view paper- Downloaded 955 times
- Download rankings, all-time:
- Site-wide: 22,386
- In genetic and genomic medicine: 76
- Year to date:
- Site-wide: 11,160
- Since beginning of last month:
- Site-wide: 13,606
Can education be personalised using pupils’ genetic data?
genetics more details view paper- Downloaded 941 times
- Download rankings, all-time:
- Site-wide: 22,918
- In genetics: 1,108
- Year to date:
- Site-wide: 90,221
- Since beginning of last month:
- Site-wide: 97,199
Genetic Association Study of Childhood Aggression across raters, instruments and age
genomics more details view paper- Downloaded 916 times
- Download rankings, all-time:
- Site-wide: 23,863
- In genomics: 2,301
- Year to date:
- Site-wide: 14,869
- Since beginning of last month:
- Site-wide: 8,636
Apolipoprotein B underlies the causal relationship of circulating blood lipids with coronary heart disease
cardiovascular medicine more details view paper- Downloaded 908 times
- Download rankings, all-time:
- Site-wide: 24,133
- In cardiovascular medicine: 34
- Year to date:
- Site-wide: 70,899
- Since beginning of last month:
- Site-wide: 58,809
Imprinted loci may be more widespread in humans than previously appreciated and enable limited assignment of parental allelic transmissions in unrelated individuals
genomics more details view paper- Downloaded 898 times
- Download rankings, all-time:
- Site-wide: 24,536
- In genomics: 2,345
- Year to date:
- Site-wide: 52,164
- Since beginning of last month:
- Site-wide: 46,435
Improving the visualisation, interpretation and analysis of two-sample summary data Mendelian randomization via the radial plot and radial regression
epidemiology more details view paper- Downloaded 847 times
- Download rankings, all-time:
- Site-wide: 26,647
- In epidemiology: 1,447
- Year to date:
- Site-wide: 119,321
- Since beginning of last month:
- Site-wide: 116,909
Genetic Epidemiology And Mendelian Randomization For Informing Disease Therapeutics: Conceptual And Methodological Challenges
genetics more details view paper- Downloaded 792 times
- Download rankings, all-time:
- Site-wide: 29,222
- In genetics: 1,418
- Year to date:
- Site-wide: 124,543
- Since beginning of last month:
- Site-wide: 107,741
Causal Inference for Heritable Phenotypic Risk Factors Using Heterogeneous Genetic Instruments
genetics more details view paper- Downloaded 790 times
- Download rankings, all-time:
- Site-wide: 29,343
- In genetics: 1,426
- Year to date:
- Site-wide: 17,834
- Since beginning of last month:
- Site-wide: 19,620
The Causal Effect Of Educational Attainment On Alzheimer's Disease: A Two-Sample Mendelian Randomization Study
epidemiology more details view paper- Downloaded 785 times
- Download rankings, all-time:
- Site-wide: 29,604
- In epidemiology: 1,543
- Year to date:
- Site-wide: 65,105
- Since beginning of last month:
- Site-wide: 63,122
MR-TRYX: A Mendelian randomization framework that exploits horizontal pleiotropy to infer novel causal pathways
bioinformatics more details view paper- Downloaded 782 times
- Download rankings, all-time:
- Site-wide: 29,785
- In bioinformatics: 3,408
- Year to date:
- Site-wide: 75,550
- Since beginning of last month:
- Site-wide: 95,862
Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways
genetics more details view paper- Downloaded 781 times
- Download rankings, all-time:
- Site-wide: 29,817
- In genetics: 1,444
- Year to date:
- Site-wide: 70,279
- Since beginning of last month:
- Site-wide: 87,172
Educational attainment impacts drinking behaviors and risk for alcohol dependence: results from a two-sample Mendelian randomization study with ~780 000 participants
epidemiology more details view paper- Downloaded 758 times
- Download rankings, all-time:
- Site-wide: 31,098
- In epidemiology: 1,595
- Year to date:
- Site-wide: 42,750
- Since beginning of last month:
- Site-wide: 34,928
Integrating Mendelian randomization and multiple-trait colocalization to uncover cell-specific inflammatory drivers of autoimmune and atopic disease
genetics more details view paper- Downloaded 746 times
- Download rankings, all-time:
- Site-wide: 31,782
- In genetics: 1,538
- Year to date:
- Site-wide: 90,268
- Since beginning of last month:
- Site-wide: 87,325
Examining the genetic influences of educational attainment and the validity of value-added measures of progress
genetics more details view paper- Downloaded 739 times
- Download rankings, all-time:
- Site-wide: 32,213
- In genetics: 1,559
- Year to date:
- Site-wide: 118,554
- Since beginning of last month:
- Site-wide: 112,076
Disentangling genetically confounded polygenic associations between Attention-Deficit/Hyperactivity Disorder, literacy and language
genetics more details view paper- Downloaded 734 times
- Download rankings, all-time:
- Site-wide: 32,564
- In genetics: 1,577
- Year to date:
- Site-wide: 83,301
- Since beginning of last month:
- Site-wide: 75,181
Using genetics to examine a general liability to childhood psychopathology
genetics more details view paper- Downloaded 732 times
- Download rankings, all-time:
- Site-wide: 32,701
- In genetics: 1,583
- Year to date:
- Site-wide: 80,069
- Since beginning of last month:
- Site-wide: 104,344
Can the impact of childhood adiposity on disease risk be reversed? A Mendelian randomization study
epidemiology more details view paper- Downloaded 732 times
- Download rankings, all-time:
- Site-wide: 32,667
- In epidemiology: 1,643
- Year to date:
- Site-wide: 68,858
- Since beginning of last month:
- Site-wide: 58,449
Genetic liability for schizophrenia and childhood psychopathology in the general population
psychiatry and clinical psychology more details view paper- Downloaded 715 times
- Download rankings, all-time:
- Site-wide: 33,620
- In psychiatry and clinical psychology: 106
- Year to date:
- Site-wide: 5,194
- Since beginning of last month:
- Site-wide: 6,834
Trans-ethnic genome-wide association study provides insight into effector genes and molecular mechanisms for kidney function and highlights a causal effect on kidney-specific disease aetiologies
genetics more details view paper- Downloaded 713 times
- Download rankings, all-time:
- Site-wide: 33,770
- In genetics: 1,634
- Year to date:
- Site-wide: 120,987
- Since beginning of last month:
- Site-wide: 110,876
Disentangling causal relationships between inflammatory markers and depression: a bidirectional Mendelian randomization analysis
genomics more details view paper- Downloaded 711 times
- Download rankings, all-time:
- Site-wide: 33,914
- In genomics: 2,970
- Year to date:
- Site-wide: 19,581
- Since beginning of last month:
- Site-wide: 18,179
Consistency of non-cognitive skills and their relation to educational outcomes in a UK cohort
genetics more details view paper- Downloaded 698 times
- Download rankings, all-time:
- Site-wide: 34,845
- In genetics: 1,668
- Year to date:
- Site-wide: 29,622
- Since beginning of last month:
- Site-wide: 26,765
Genomic and phenomic insights from an atlas of genetic effects on DNA methylation
genetic and genomic medicine more details view paper- Downloaded 689 times
- Download rankings, all-time:
- Site-wide: 35,421
- In genetic and genomic medicine: 109
- Year to date:
- Site-wide: 9,719
- Since beginning of last month:
- Site-wide: 10,458
Investigating causality between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization
genetics more details view paper- Downloaded 687 times
- Download rankings, all-time:
- Site-wide: 35,567
- In genetics: 1,703
- Year to date:
- Site-wide: 95,306
- Since beginning of last month:
- Site-wide: 91,327
Common and rare variant association analyses in Amyotrophic Lateral Sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology
neurology more details view paper- Downloaded 685 times
- Download rankings, all-time:
- Site-wide: 35,700
- In neurology: 64
- Year to date:
- Site-wide: 1,913
- Since beginning of last month:
- Site-wide: 553
Prioritizing putative influential genes in early life cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization
genetics more details view paper- Downloaded 675 times
- Download rankings, all-time:
- Site-wide: 36,420
- In genetics: 1,739
- Year to date:
- Site-wide: 124,571
- Since beginning of last month:
- Site-wide: 127,767
Detecting heterogeneity of intervention effects using analysis and meta-analysis of differences in variance between arms of a trial
epidemiology more details view paper- Downloaded 674 times
- Download rankings, all-time:
- Site-wide: 36,479
- In epidemiology: 1,783
- Year to date:
- Site-wide: 36,667
- Since beginning of last month:
- Site-wide: 39,263
The molecular genetics of participation in the Avon Longitudinal Study of Parents and Children
genetics more details view paper- Downloaded 670 times
- Download rankings, all-time:
- Site-wide: 36,801
- In genetics: 1,754
- Year to date:
- Site-wide: 120,370
- Since beginning of last month:
- Site-wide: 97,048
Evidence that low socioeconomic position accentuates genetic susceptibility to obesity
genetics more details view paper- Downloaded 669 times
- Download rankings, all-time:
- Site-wide: 36,858
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Distinct Blood DNA Methylation Profiles In Subtypes Of Orofacial Cleft
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Slope-Hunter: A robust method for index-event bias correction in genome-wide association studies of subsequent traits
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Orienting The Causal Relationship Between Imprecisely Measured Traits Using Genetic Instruments
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Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment
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Education and coronary heart disease: a Mendelian randomization study
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Appraising the causal relevance of DNA methylation for risk of lung cancer
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Genetic predictors of participation in optional components of UK Biobank
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Y chromosome and mitochondrial DNA haplogroups across behavioural traits in children from the general population
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Assessing the causal role of body mass index on cardiovascular health in young adults: Mendelian randomization and recall-by-genotype analyses
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Early metabolic features of genetic liability to type 2 diabetes: cohort study with repeated metabolomics across early life
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Genetic architecture of early childhood growth phenotypes gives insights into their link with later obesity
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Within-sibship GWAS improve estimates of direct genetic effects
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Association of pre-pregnancy body mass index with future offspring metabolic profile: findings from three independent European birth cohorts
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Is disrupted sleep a risk factor for Alzheimers disease? Evidence from a two-sample Mendelian randomization analysis
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Low-frequency variation in TP53 has large effects on head circumference and intracranial volume
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Mendelian randomisation analysis of the effect of educational attainment and cognitive ability on smoking behaviour
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Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility
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The MRC IEU OpenGWAS data infrastructure
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Metabolic signatures of birth weight in 18288 adolescents and adults
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Cigarette smoking and personality: Investigating causality using Mendelian randomization
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Conditioning on a collider may induce spurious associations: Do the results of Gale et al. (2017) support a protective effect of neuroticism in population sub-groups?
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Investigating causality in associations between education and smoking: A two-sample Mendelian randomization study
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The median and the mode as robust meta-analysis methods in the presence of small study effects
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The Parkinsons Disease Mendelian Randomization Research Portal
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What explains the effect of education on cardiovascular disease? Applying Mendelian randomization to identify the consequences of education inequality
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Genetic liability to schizophrenia is associated with exposure to traumatic events in childhood
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Systematic evaluation of the causal relationship between DNA methylation and C-reactive protein
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Evaluating the effects of alcohol and tobacco use on cardiovascular disease using multivariable Mendelian randomization
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Mendelian Randomization analysis reveals a causal influence of circulating sclerostin levels on bone mineral density and fractures
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A cross-disorder MR-pheWAS of 5 major psychiatric disorders in UK Biobank
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The causal effect of adiposity on hospital costs: Mendelian Randomization analysis of over 300,000 individuals from the UK Biobank
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Epigenetic regulation of PAR4-related platelet activation: mechanistic links between environmental exposure and cardiovascular disease
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Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology
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Trans-ethnic Mendelian randomization study reveals causal relationships between cardio-metabolic factors and chronic kidney disease
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PCSK9 genetic variants, life-long lowering of LDL-cholesterol and cognition: a large-scale Mendelian randomization study
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Is genetic liability to ADHD and ASD causally linked to educational attainment?
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Evaluating causal associations between previously reported risk factors and epithelial ovarian cancer: a Mendelian randomization analysis
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The effect of body mass index on smoking behaviour and nicotine metabolism: a Mendelian randomization study
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Association Between Genetically Elevated Levels Of Inflammatory Biomarkers And Risk Of Schizophrenia: A Two-Sample Mendelian Randomisation Study
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CETP inhibition and ADCY9 genotype: evidence of a qualitative pharmacogenetic interaction in cardiovascular disease?
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Schizophrenia risk and reproductive success: A Mendelian randomization study.
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Investigating the combined association of BMI and alcohol consumption on liver disease and biomarkers: a Mendelian randomization study of over 90 000 adults from the Copenhagen General Population Study
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Circulating selenium and prostate cancer risk: a Mendelian randomization analysis
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MR-pheWAS with stratification and interaction: Searching for the causal effects of smoking heaviness identified an effect on facial aging
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Examining the effect of smoking on suicidal ideation and attempts: A Mendelian randomisation study
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Testing the causal effects between subjective wellbeing and physical health using Mendelian randomisation
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The use of negative control outcomes in Mendelian Randomisation to detect potential population stratification or selection bias.
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The association between adiposity and inpatient hospital costs in the UK Biobank cohort
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Identifying novel subtypes of irritability using a developmental genetic approach
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The effect of plasma lipids and lipid lowering interventions on bone mineral density: a Mendelian randomization study
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Lipoprotein Signatures of Cholesteryl Ester Transfer Protein and HMG-CoA Reductase Inhibition
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Assortative mating and within-spouse pair comparisons
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Paternal body mass index and offspring DNA methylation: findings from the PACE consortium
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A rare SMAD9 mutation identifies the BMP signalling pathway as a potential osteoanabolic target
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Partitioning Phenotypic Variance Due To Parent-Of-Origin Effects Using Genomic Relatedness Matrices
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Effects of apolipoprotein B on the lifespan and risks of major disease including type 2 diabetes: a Mendelian randomization analysis using outcomes in first-degree relatives
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The Multivariate Genome-wide Architecture of Interrelated Literacy, Language and Working Memory Skills Reveals Distinct Etiologies
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Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study
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Sex differences in cardiometabolic traits at four life stages: cohort study with repeated metabolomics
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Unhealthy Behaviours and Parkinsons Disease: A Mendelian Randomisation Study
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DNA methylation mediates genetic liability to non-syndromic cleft lip/palate
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Epigenetic biomarkers of ageing are predictive of mortality risk in a longitudinal clinical cohort of individuals diagnosed with oropharyngeal cancer.
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A robust mean and variance test with application to high-dimensional phenotypes
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Do maternal intrauterine environmental influences that lower offspring birthweight causally increase offspring cardiometabolic risk factors in later life? A Mendelian randomization study of 45,849 genotyped parent offspring pairs in the HUNT study
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Estimating the causal effect of genetic liability to prevalent disease on hospital costs using Mendelian Randomization
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Interaction-based Mendelian randomization with measured and unmeasured gene-by-covariate interactions
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Mendelian randomisation with coarsened exposures
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The relationship between open angle glaucoma, optic disc morphology and Alzheimer's Disease: a Mendelian randomization study
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Proxy gene-by-environment Mendelian randomization study confirms a causal effect of maternal smoking on offspring birthweight, but little evidence of long-term influences on offspring health
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Biomarker de-Mendelization: principles, potentials and limitations of a strategy to improve biomarker prediction by reducing the component of variance explained by genotype
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Does Smoking Cause Lower Educational Attainment and General Cognitive Ability? Triangulation of causal evidence using multiple study designs
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Educational inequalities in statin treatment for preventing cardiovascular disease: cross-sectional analysis of UK Biobank
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Mendelian randomization does not support serum calcium in prostate cancer risk
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Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization
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Developmental changes within the genetic architecture of social communication behaviour: A multivariate study of genetic variance in unrelated individuals
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Evaluating the direct effects of childhood adiposity on adult systemic metabolism: A multivariable Mendelian randomization analysis
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Effects of adiposity on the human plasma proteome: Observational and Mendelian randomization estimates
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The role of school enjoyment in the association between externalising and depressive symptoms and academic attainment: findings from a UK prospective cohort study
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Association between breastfeeding and DNA methylation over the life course: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC)
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The effect of smoking on multiple sclerosis: a mendelian randomization study
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A phenome-wide multi-directional Mendelian randomization analysis of atrial fibrillation
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- Site-wide: 33,056
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- Site-wide: 29,964
Examining the bidirectional association between emotion recognition and ASD symptoms using observational and genetic analyses
genetic and genomic medicine more details view paper- Downloaded 225 times
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- Site-wide: 101,547
- In genetic and genomic medicine: 415
- Year to date:
- Site-wide: 66,624
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Association of genetic liability to smoking initiation with e-cigarette use in young adults.
epidemiology more details view paper- Downloaded 224 times
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- Site-wide: 101,722
- In epidemiology: 4,187
- Year to date:
- Site-wide: 38,203
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Exploring the causal effects of genetic liability to ADHD and Autism on Alzheimer's disease
genetics more details view paper- Downloaded 224 times
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- Site-wide: 101,663
- In genetics: 4,520
- Year to date:
- Site-wide: 96,104
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Using human genetics to understand the causes and consequences of circulating cardiac troponin I in the general population
epidemiology more details view paper- Downloaded 219 times
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- Site-wide: 102,827
- In epidemiology: 4,239
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Evaluating the effects of cardiometabolic exposures on circulating proteins which may contribute to SARS-CoV-2 severity
epidemiology more details view paper- Downloaded 219 times
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- Site-wide: 102,834
- In epidemiology: 4,241
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Risk of death among teachers in England and Wales during the Covid19 pandemic
epidemiology more details view paper- Downloaded 216 times
- Download rankings, all-time:
- Site-wide: 103,550
- In epidemiology: 4,274
- Year to date:
- Site-wide: 9,923
- Since beginning of last month:
- Site-wide: 5,279
Role of Inflammation in Depression and Anxiety: Tests for Disorder Specificity, Linearity and Potential Causality of Association in the UK Biobank
psychiatry and clinical psychology more details view paper- Downloaded 202 times
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- Site-wide: 106,646
- In psychiatry and clinical psychology: 425
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- Site-wide: 10,868
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- Site-wide: 15,375
The role of the metabolic profile in mediating the relationship between body mass index and left ventricular mass in adolescents: analysis of a prospective cohort study
epidemiology more details view paper- Downloaded 192 times
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- Site-wide: 108,963
- In epidemiology: 4,481
- Year to date:
- Site-wide: 89,386
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- Site-wide: 77,408
Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: a Mendelian randomization study
epidemiology more details view paper- Downloaded 190 times
- Download rankings, all-time:
- Site-wide: 109,289
- In epidemiology: 4,508
- Year to date:
- Site-wide: 36,338
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- Site-wide: 24,624
Interrogating structural inequalities in COVID-19 Mortality in England and Wales
epidemiology more details view paper- Downloaded 185 times
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- Site-wide: 110,554
- In epidemiology: 4,554
- Year to date:
- Site-wide: 12,199
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- Site-wide: 16,871
Causal effects of circulating cytokine concentrations on risk of Alzheimers disease: A bidirectional two-sample Mendelian randomization study
genetic and genomic medicine more details view paper- Downloaded 177 times
- Download rankings, all-time:
- Site-wide: 112,226
- In genetic and genomic medicine: 501
- Year to date:
- Site-wide: 30,974
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- Site-wide: 22,586
Examining the possible causal relationship between Lung Function, COPD and Alzheimers Disease. A Mendelian Randomization Study
respiratory medicine more details view paper- Downloaded 164 times
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- Site-wide: 114,998
- In respiratory medicine: 209
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- Site-wide: 42,705
Interpreting Mendelian randomization estimates of the effects of categorical exposures such as disease status and educational attainment
epidemiology more details view paper- Downloaded 154 times
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- Site-wide: 116,902
- In epidemiology: 4,800
- Year to date:
- Site-wide: 42,417
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- Site-wide: 34,502
Identifying intergenerational risk factors for ADHD symptoms using polygenic scores in the Norwegian Mother, Father and Child Cohort
psychiatry and clinical psychology more details view paper- Downloaded 154 times
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- Site-wide: 116,927
- In psychiatry and clinical psychology: 517
- Year to date:
- Site-wide: 15,422
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- Site-wide: 12,067
An Informatics Consult approach for generating clinical evidence for treatment decisions
health informatics more details view paper- Downloaded 141 times
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- Site-wide: 119,583
- In health informatics: 454
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Body muscle gain and markers of cardiovascular disease susceptibility in young adulthood: prospective cohort study
epidemiology more details view paper- Downloaded 141 times
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- Site-wide: 119,702
- In epidemiology: 4,893
- Year to date:
- Site-wide: 113,478
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- Site-wide: 103,191
Genetically-proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers
epidemiology more details view paper- Downloaded 135 times
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- Site-wide: 120,742
- In epidemiology: 4,934
- Year to date:
- Site-wide: 18,211
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- Site-wide: 5,362
Epidemiology and Genetics of Preserved Ratio Impaired SpiroMetry (PRISm): An Analysis of UK Biobank
respiratory medicine more details view paper- Downloaded 128 times
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- Site-wide: 122,251
- In respiratory medicine: 232
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- Site-wide: 74,207
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- Site-wide: 65,200
Cross-sectional association of blood pressure variability and night-time dipping with cardiac structure in adolescents
epidemiology more details view paper- Downloaded 99 times
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- Site-wide: 127,564
- In epidemiology: 5,155
- Year to date:
- Site-wide: 68,003
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- Site-wide: 49,617
Sex-specific associations of adiposity with cardiometabolic traits: multi-life-stage cohort study with repeat metabolomics
epidemiology more details view paper- Downloaded 77 times
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- Site-wide: 130,878
- In epidemiology: 5,284
- Year to date:
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- Site-wide: 55,277
Puberty and sex-specific trajectories of systolic blood pressure: a prospective cohort study
epidemiology more details view paper- Downloaded 66 times
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- Site-wide: 132,219
- In epidemiology: 5,343
- Year to date:
- Site-wide: 39,552
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Educational attainment as a modifier of the effect of polygenic scores for cardiovascular risk factors: cross-sectional and prospective analysis of UK Biobank
genetic and genomic medicine more details view paper- Downloaded 48 times
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- Site-wide: 133,722
- In genetic and genomic medicine: 665
- Year to date:
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Using multivariable Mendelian randomization to estimate the causal effect of bone mineral density on osteoarthritis risk, independent of body mass index
genetic and genomic medicine more details view paper- Downloaded 46 times
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- Site-wide: 133,826
- In genetic and genomic medicine: 667
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PanLingua
News
- 27 Nov 2020: The website and API now include results pulled from medRxiv as well as bioRxiv.
- 18 Dec 2019: We're pleased to announce PanLingua, a new tool that enables you to search for machine-translated bioRxiv preprints using more than 100 different languages.
- 21 May 2019: PLOS Biology has published a community page about Rxivist.org and its design.
- 10 May 2019: The paper analyzing the Rxivist dataset has been published at eLife.
- 1 Mar 2019: We now have summary statistics about bioRxiv downloads and submissions.
- 8 Feb 2019: Data from Altmetric is now available on the Rxivist details page for every preprint. Look for the "donut" under the download metrics.
- 30 Jan 2019: preLights has featured the Rxivist preprint and written about our findings.
- 22 Jan 2019: Nature just published an article about Rxivist and our data.
- 13 Jan 2019: The Rxivist preprint is live!