Author: Chris Wallace

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Preprints

Comparison of sparse biclustering algorithms for gene expression datasets

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Fine mapping chromatin contacts in capture Hi-C data

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Type 1 diabetes genome-wide association analysis with imputation identifies five new risk regions

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Recent thymic emigrants produce antimicrobial IL-8, express complement receptors and are precursors of a tissue-homing Th8 lineage of memory cells

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Probability-based approaches for identifying low-titer antibody responses against SARS-CoV-2

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Chromosome contacts in activated T cells identify autoimmune disease candidate genes

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A method for identifying genetic heterogeneity within phenotypically-defined disease subgroups

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DNA methylation oscillation defines classes of enhancers

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Informed dimension reduction of clinically-related genome-wide association summary data characterises cross-trait axes of genetic risk

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Multivariate genome-wide association analysis of a cytokine network reveals variants with widespread immune, haematological and cardiometabolic pleiotropy

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simGWAS: a fast method for simulation of large scale case-control GWAS summary statistics

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Dissection of a complex disease susceptibility region using a Bayesian stochastic search approach to fine mapping

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Genetically distinct clinical subsets, and associations with asthma and eosinophil abundance, within Eosinophilic Granulomatosis with Polyangiitis

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Functional effects of variation in transcription factor binding highlight long-range gene regulation by epromoters

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Accurate error control in high dimensional association testing using conditional false discovery rates

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Heterogeneity of cognitive decline in dementia: a failed attempt to take into account variable time-zero severity

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Cells With Treg-Specific FOXP3 Demethylation But Low CD25 Are Prevalent In Autoimmunity

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A rare IL2RA haplotype identifies SNP rs61839660 as causal for autoimmunity

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Eliciting priors and relaxing the single causal variant assumption in colocalisation analyses

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Improving the coverage of credible sets in Bayesian genetic fine-mapping

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A Pleiotropy-Informed Bayesian False Discovery Rate adapted to a Shared Control Design Finds New Disease Associations From GWAS Summary Statistics

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Sharing information between related diseases using Bayesian joint fine mapping increases accuracy and identifies novel associations in six immune mediated diseases

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RapidoPGS: A rapid polygenic score calculator for summary GWAS data without validation dataset

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BaseQTL: a Bayesian method to detect eQTLs from RNA-seq data with or without genotypes

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Resolving mechanisms of immune-mediated disease in primary CD4 T cells

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EPISPOT: an epigenome-driven approach for detecting and interpreting hotspots in molecular QTL studies

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Improved consistency in estimates of conditional false discovery rates increases power relative to both existing methods and parametric estimators

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Multi-tissue transcriptome-wide association studies

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Seropositivity in blood donors and pregnant women during 9-months of SARS-CoV-2 transmission in Stockholm, Sweden

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Leveraging auxiliary data from arbitrary distributions to boost GWAS discovery with Flexible cFDR

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Consensus clustering for Bayesian mixture models

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