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Author: Peter M Visscher

Rankings

  • All-time downloads: 113,964 (rank: 256 out of 423,771)
  • Categories:
    • bioinformatics: 2,288 (rank: 4,931 (tie) out of 35,889)
    • genetics: 89,944 (rank: 18 out of 37,726)
    • genomics: 20,638 (rank: 433 out of 44,222)
    • neuroscience: 1,094 (rank: 16,130 (tie) out of 71,570)

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Preprints

Recovery of trait heritability from whole genome sequence data

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Expanding Parkinson's disease genetics: novel risk loci, genomic context, causal insights and heritable risk.

genetics more details view paper
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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

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Genetic Consequences of Social Stratification in Great Britain

genetics more details view paper
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New mutations, old statistical challenges

genetics more details view paper
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MTAG: Multi-Trait Analysis of GWAS

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Meta-analysis of genome-wide association studies for height and body mass index in ~700,000 individuals of European ancestry

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Commentary on "Limitations of GCTA as a solution to the missing heritability problem"

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Improved polygenic prediction by Bayesian multiple regression on summary statistics

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    • In genetics: 191 out of 4,997
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Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits.

genetics more details view paper
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A resource-efficient tool for mixed model association analysis of large-scale data

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    • In genetics: 221 out of 4,997
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Widespread signatures of negative selection in the genetic architecture of human complex traits

genetics more details view paper
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GWAS on family history of Alzheimer's disease

genetics more details view paper
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    • In genetics: 309 out of 4,997
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Causal associations between risk factors and common diseases inferred from GWAS summary data

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    • In genetics: 367 out of 4,997
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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

genetics more details view paper
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    • In genetics: 373 out of 4,997
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Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry

genetics more details view paper
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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

genomics more details view paper
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    • In genomics: 1,110 out of 6,221
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Mixed Model with Correction for Case-Control Ascertainment Increases Association Power

genetics more details view paper
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    • In genetics: 510 out of 4,997
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Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

genetics more details view paper
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    • In genetics: 517 out of 4,997
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Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank

genetics more details view paper
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    • In genetics: 541 out of 4,997
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Equivalence of LD-Score Regression and Individual-Level-Data Methods

genetics more details view paper
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    • In genetics: 552 out of 4,997
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Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations

genetics more details view paper
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    • In genetics: 589 out of 4,997
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Bayesian reassessment of the epigenetic architecture of complex traits

genomics more details view paper
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    • In genomics: 1,284 out of 6,221
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Parkinson disease age of onset GWAS: defining heritability, genetic loci and a-synuclein mechanisms

genetics more details view paper
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Improved prediction of chronological age from DNA methylation limits it as a biomarker of ageing

bioinformatics more details view paper
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    • In bioinformatics: 1,490 out of 9,217
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Imprint of Assortative Mating on the Human Genome

genetics more details view paper
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    • In genetics: 619 out of 4,997
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Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

genetics more details view paper
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    • In genetics: 686 out of 4,997
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Bayesian analysis of GWAS summary data reveals differential signatures of natural selection across human complex traits and functional genomic categories

genetics more details view paper
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    • In genetics: 733 out of 4,997
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OSCA: a tool for omic-data-based complex trait analysis

bioinformatics more details view paper
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Narrow-sense heritability estimation of complex traits using identity-by-descent information.

genetics more details view paper
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Expectation of the intercept from bivariate LD score regression in the presence of population stratification

genetics more details view paper
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Identification of 55,000 Replicated DNA Methylation QTL

genomics more details view paper
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    • In genomics: 1,739 out of 6,221
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Epigenetic prediction of complex traits and death

genomics more details view paper
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Novel susceptibility loci and genetic regulation mechanisms for type 2 diabetes

genetics more details view paper
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GWAS of epigenetic ageing rates in blood reveals a critical role for TERT

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Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

genetics more details view paper
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Widespread associations between grey matter structure and the human phenome

neuroscience more details view paper
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Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration.

genetics more details view paper
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Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins

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Quantifying genetic heterogeneity between continental populations for human height and body mass index

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Constraints on eQTL fine mapping in the presence of multi-site local regulation of gene expression

genetics more details view paper
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Across-cohort QC analyses of genome-wide association study summary statistics from complex traits

genetics more details view paper
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No evidence for social genetic effects or genetic similarity among friends beyond that due to population stratification: a reappraisal of Domingue et al (2018)

genetics more details view paper
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The effect of X-linked dosage compensation on complex trait variation

genetics more details view paper
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Genome-wide association study of gastrointestinal disorders reinforces the link between the digestive tract and the nervous system

genomics more details view paper
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Genetic analyses of medication-use and implications for precision medicine

genetics more details view paper
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Integrative omics approach to identify the molecular architecture of inflammatory protein levels in healthy older adults

genomics more details view paper
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Improved analyses of GWAS summary statistics by reducing data heterogeneity and errors

genetics more details view paper
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Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936

neuroscience more details view paper
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An epigenome-wide association study of sex-specific chronological ageing

genomics more details view paper
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Rare Genetic Variants Underlie Outlying levels of DNA Methylation and Gene-Expression

genetics more details view paper
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Epigenetic signatures of starting and stopping smoking

genomics more details view paper
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Using prior information from humans to prioritize genes and gene-associated variants for complex traits in livestock

genetics more details view paper
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Variation in VKORC1 is associated with vascular dementia

genetics more details view paper
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