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Author: Jian Yang

Rankings

  • All-time downloads: 137,024 (rank: 601 )
  • Categories:
    • bioengineering: 138 (rank: 14,133 (tie) )
    • bioinformatics: 6,233 (rank: 1,736 )
    • developmental biology: 7,152 (rank: 105 )
    • evolutionary biology: 491 (rank: 13,571 (tie) )
    • genetic and genomic medicine: 1,798 (rank: 1,010 (tie) )
    • genetics: 98,966 (rank: 17 )
    • genomics: 18,191 (rank: 624 )
    • infectious diseases: 438 (rank: 30,457 (tie) )
    • microbiology: 639 (rank: 21,184 (tie) )
    • neuroscience: 815 (rank: 28,158 (tie) )
    • pharmacology and toxicology: 411 (rank: 3,248 (tie) )
    • psychiatry and clinical psychology: 246 (rank: 3,608 (tie) )
    • radiology and imaging: 1,506 (rank: 177 (tie) )

Downloads per author, site-wide

Preprints

Recovery of trait heritability from whole genome sequence data

genetics more details view paper
  • Downloaded 11,629 times
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    • Site-wide: 655
    • In genetics: 17
  • Year to date:
    • Site-wide: 2,287
  • Since beginning of last month:
    • Site-wide: 2,386

Expanding Parkinson's disease genetics: novel risk loci, genomic context, causal insights and heritable risk.

genetics more details view paper
  • Downloaded 10,808 times
  • Download rankings, all-time:
    • Site-wide: 724
    • In genetics: 20
  • Year to date:
    • Site-wide: 3,360
  • Since beginning of last month:
    • Site-wide: 3,846

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

genomics more details view paper
  • Downloaded 9,971 times
  • Download rankings, all-time:
    • Site-wide: 807
    • In genomics: 63
  • Year to date:
    • Site-wide: 1,365
  • Since beginning of last month:
    • Site-wide: 1,351

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

genetics more details view paper
  • Downloaded 9,392 times
  • Download rankings, all-time:
    • Site-wide: 870
    • In genetics: 26
  • Year to date:
    • Site-wide: 31,379
  • Since beginning of last month:
    • Site-wide: 33,428

Genetic Consequences of Social Stratification in Great Britain

genetics more details view paper
  • Downloaded 7,745 times
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    • Site-wide: 1,114
    • In genetics: 35
  • Year to date:
    • Site-wide: 9,753
  • Since beginning of last month:
    • Site-wide: 9,169

LD Score Regression Distinguishes Confounding from Polygenicity in Genome-Wide Association Studies

genomics more details view paper
  • Downloaded 7,173 times
  • Download rankings, all-time:
    • Site-wide: 1,231
    • In genomics: 115
  • Year to date:
    • Site-wide: 69,137
  • Since beginning of last month:
    • Site-wide: 71,869

Meta-analysis of genome-wide association studies for height and body mass index in ~700,000 individuals of European ancestry

genetics more details view paper
  • Downloaded 6,620 times
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    • Site-wide: 1,351
    • In genetics: 46
  • Year to date:
    • Site-wide: 18,234
  • Since beginning of last month:
    • Site-wide: 14,676

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

genetics more details view paper
  • Downloaded 3,541 times
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    • Site-wide: 3,262
    • In genetics: 126
  • Year to date:
    • Site-wide: 30,789
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    • Site-wide: 29,047

Human Naïve Epiblast Cells Possess Unrestricted Lineage Potential

developmental biology more details view paper
  • Downloaded 3,490 times
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    • Site-wide: 3,339
    • In developmental biology: 29
  • Year to date:
    • Site-wide: 1,638
  • Since beginning of last month:
    • Site-wide: 1,384

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

bioinformatics more details view paper
  • Downloaded 3,388 times
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    • Site-wide: 3,475
    • In bioinformatics: 355
  • Year to date:
    • Site-wide: 57,677
  • Since beginning of last month:
    • Site-wide: 56,910

Haplotypes of common SNPs can explain missing heritability of complex diseases

genetics more details view paper
  • Downloaded 3,080 times
  • Download rankings, all-time:
    • Site-wide: 3,983
    • In genetics: 169
  • Year to date:
    • Site-wide: 81,380
  • Since beginning of last month:
    • Site-wide: 74,883

Commentary on "Limitations of GCTA as a solution to the missing heritability problem"

genetics more details view paper
  • Downloaded 2,953 times
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    • Site-wide: 4,217
    • In genetics: 183
  • Year to date:
    • Site-wide: 24,315
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    • Site-wide: 16,523

A resource-efficient tool for mixed model association analysis of large-scale data

genetics more details view paper
  • Downloaded 2,782 times
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    • Site-wide: 4,593
    • In genetics: 202
  • Year to date:
    • Site-wide: 11,029
  • Since beginning of last month:
    • Site-wide: 7,333

Improved polygenic prediction by Bayesian multiple regression on summary statistics

genetics more details view paper
  • Downloaded 2,772 times
  • Download rankings, all-time:
    • Site-wide: 4,621
    • In genetics: 204
  • Year to date:
    • Site-wide: 66,953
  • Since beginning of last month:
    • Site-wide: 74,354

Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits.

genetics more details view paper
  • Downloaded 2,631 times
  • Download rankings, all-time:
    • Site-wide: 4,980
    • In genetics: 224
  • Year to date:
    • Site-wide: 83,672
  • Since beginning of last month:
    • Site-wide: 89,337

Genomic evaluation of circulating proteins for drug target characterisation and precision medicine

genetics more details view paper
  • Downloaded 2,327 times
  • Download rankings, all-time:
    • Site-wide: 6,003
    • In genetics: 281
  • Year to date:
    • Site-wide: 6,426
  • Since beginning of last month:
    • Site-wide: 6,629

Widespread signatures of negative selection in the genetic architecture of human complex traits

genetics more details view paper
  • Downloaded 2,240 times
  • Download rankings, all-time:
    • Site-wide: 6,332
    • In genetics: 302
  • Year to date:
    • Site-wide: 51,625
  • Since beginning of last month:
    • Site-wide: 33,140

GWAS on family history of Alzheimer's disease

genetics more details view paper
  • Downloaded 1,990 times
  • Download rankings, all-time:
    • Site-wide: 7,521
    • In genetics: 353
  • Year to date:
    • Site-wide: 63,035
  • Since beginning of last month:
    • Site-wide: 49,226

Causal associations between risk factors and common diseases inferred from GWAS summary data

genetics more details view paper
  • Downloaded 1,775 times
  • Download rankings, all-time:
    • Site-wide: 8,947
    • In genetics: 427
  • Year to date:
    • Site-wide: 93,235
  • Since beginning of last month:
    • Site-wide: 97,091

Establishment In Culture Of Expanded Potential Stem Cells

developmental biology more details view paper
  • Downloaded 1,715 times
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    • Site-wide: 9,432
    • In developmental biology: 128
  • Year to date:
    • Site-wide: 67,000
  • Since beginning of last month:
    • Site-wide: 61,634

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

genetics more details view paper
  • Downloaded 1,713 times
  • Download rankings, all-time:
    • Site-wide: 9,445
    • In genetics: 453
  • Year to date:
    • Site-wide: 75,535
  • Since beginning of last month:
    • Site-wide: 80,623

Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry

genetics more details view paper
  • Downloaded 1,613 times
  • Download rankings, all-time:
    • Site-wide: 10,299
    • In genetics: 497
  • Year to date:
    • Site-wide: 54,446
  • Since beginning of last month:
    • Site-wide: 45,825

Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank

genetics more details view paper
  • Downloaded 1,501 times
  • Download rankings, all-time:
    • Site-wide: 11,406
    • In genetics: 546
  • Year to date:
    • Site-wide: 41,510
  • Since beginning of last month:
    • Site-wide: 45,748

Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

genetics more details view paper
  • Downloaded 1,497 times
  • Download rankings, all-time:
    • Site-wide: 11,449
    • In genetics: 552
  • Year to date:
    • Site-wide: 17,494
  • Since beginning of last month:
    • Site-wide: 20,737

Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

genetics more details view paper
  • Downloaded 1,475 times
  • Download rankings, all-time:
    • Site-wide: 11,714
    • In genetics: 569
  • Year to date:
    • Site-wide: 80,258
  • Since beginning of last month:
    • Site-wide: 79,422

Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations

genetics more details view paper
  • Downloaded 1,429 times
  • Download rankings, all-time:
    • Site-wide: 12,304
    • In genetics: 605
  • Year to date:
    • Site-wide: 38,201
  • Since beginning of last month:
    • Site-wide: 45,338

Mixed Model with Correction for Case-Control Ascertainment Increases Association Power

genetics more details view paper
  • Downloaded 1,418 times
  • Download rankings, all-time:
    • Site-wide: 12,464
    • In genetics: 612
  • Year to date:
    • Site-wide: 105,400
  • Since beginning of last month:
    • Site-wide: 89,377

Expectation of the intercept from bivariate LD score regression in the presence of population stratification

genetics more details view paper
  • Downloaded 1,332 times
  • Download rankings, all-time:
    • Site-wide: 13,693
    • In genetics: 669
  • Year to date:
    • Site-wide: 18,768
  • Since beginning of last month:
    • Site-wide: 18,106

Bayesian analysis of GWAS summary data reveals differential signatures of natural selection across human complex traits and functional genomic categories

genetics more details view paper
  • Downloaded 1,322 times
  • Download rankings, all-time:
    • Site-wide: 13,894
    • In genetics: 676
  • Year to date:
    • Site-wide: 23,687
  • Since beginning of last month:
    • Site-wide: 19,321

Improved prediction of chronological age from DNA methylation limits it as a biomarker of ageing

bioinformatics more details view paper
  • Downloaded 1,311 times
  • Download rankings, all-time:
    • Site-wide: 14,057
    • In bioinformatics: 1,715
  • Year to date:
    • Site-wide: 57,686
  • Since beginning of last month:
    • Site-wide: 57,013

Imprint of Assortative Mating on the Human Genome

genetics more details view paper
  • Downloaded 1,278 times
  • Download rankings, all-time:
    • Site-wide: 14,611
    • In genetics: 726
  • Year to date:
    • Site-wide: 120,673
  • Since beginning of last month:
    • Site-wide: 127,703

Organizing Pneumonia of COVID-19: Time-dependent Evolution and Outcome in CT Findings

radiology and imaging more details view paper
  • Downloaded 1,231 times
  • Download rankings, all-time:
    • Site-wide: 15,467
    • In radiology and imaging: 31
  • Year to date:
    • Site-wide: 51,009
  • Since beginning of last month:
    • Site-wide: 55,005

Subtle stratification confounds estimates of heritability from rare variants

genetics more details view paper
  • Downloaded 1,160 times
  • Download rankings, all-time:
    • Site-wide: 16,884
    • In genetics: 827
  • Year to date:
    • Site-wide: 74,491
  • Since beginning of last month:
    • Site-wide: 65,858

Narrow-sense heritability estimation of complex traits using identity-by-descent information.

genetics more details view paper
  • Downloaded 1,138 times
  • Download rankings, all-time:
    • Site-wide: 17,352
    • In genetics: 849
  • Year to date:
    • Site-wide: 74,527
  • Since beginning of last month:
    • Site-wide: 65,644

OSCA: a tool for omic-data-based complex trait analysis

bioinformatics more details view paper
  • Downloaded 1,114 times
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    • Site-wide: 17,907
    • In bioinformatics: 2,149
  • Year to date:
    • Site-wide: 111,044
  • Since beginning of last month:
    • Site-wide: 111,245

A comprehensive evaluation of polygenic score methods across cohorts in psychiatric disorders

genetic and genomic medicine more details view paper
  • Downloaded 1,085 times
  • Download rankings, all-time:
    • Site-wide: 18,657
    • In genetic and genomic medicine: 62
  • Year to date:
    • Site-wide: 4,819
  • Since beginning of last month:
    • Site-wide: 4,718

Efficient estimation and applications of cross-validated genetic predictions

genetics more details view paper
  • Downloaded 1,060 times
  • Download rankings, all-time:
    • Site-wide: 19,299
    • In genetics: 937
  • Year to date:
    • Site-wide: 35,899
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    • Site-wide: 33,172

Identification of 55,000 Replicated DNA Methylation QTL

genomics more details view paper
  • Downloaded 1,047 times
  • Download rankings, all-time:
    • Site-wide: 19,628
    • In genomics: 1,975
  • Year to date:
    • Site-wide: 86,204
  • Since beginning of last month:
    • Site-wide: 80,794

Efficient RNA-mediated reprogramming of human somatic cells to naive pluripotency facilitated by tankyrase inhibition

developmental biology more details view paper
  • Downloaded 996 times
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    • Site-wide: 21,085
    • In developmental biology: 378
  • Year to date:
    • Site-wide: 36,548
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    • Site-wide: 38,784

Novel susceptibility loci and genetic regulation mechanisms for type 2 diabetes

genetics more details view paper
  • Downloaded 872 times
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    • Site-wide: 25,568
    • In genetics: 1,232
  • Year to date:
    • Site-wide: 93,144
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    • Site-wide: 62,198

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

genetics more details view paper
  • Downloaded 797 times
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    • Site-wide: 28,976
    • In genetics: 1,403
  • Year to date:
    • Site-wide: 95,574
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    • Site-wide: 79,614

Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration.

genetics more details view paper
  • Downloaded 757 times
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    • Site-wide: 31,184
    • In genetics: 1,503
  • Year to date:
    • Site-wide: 96,791
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    • Site-wide: 77,171

Quantifying genetic heterogeneity between continental populations for human height and body mass index

genetics more details view paper
  • Downloaded 741 times
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    • Site-wide: 32,079
    • In genetics: 1,550
  • Year to date:
    • Site-wide: 59,824
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    • Site-wide: 68,668

Genome-wide analyses of behavioural traits biased by misreports and longitudinal changes

genetic and genomic medicine more details view paper
  • Downloaded 713 times
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    • Site-wide: 33,784
    • In genetic and genomic medicine: 106
  • Year to date:
    • Site-wide: 37,746
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    • Site-wide: 83,202

Improved analyses of GWAS summary statistics by reducing data heterogeneity and errors

genetics more details view paper
  • Downloaded 685 times
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    • Site-wide: 35,697
    • In genetics: 1,706
  • Year to date:
    • Site-wide: 28,173
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    • Site-wide: 24,343

Constraints on eQTL fine mapping in the presence of multi-site local regulation of gene expression

genetics more details view paper
  • Downloaded 651 times
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    • Site-wide: 38,181
    • In genetics: 1,818
  • Year to date:
    • Site-wide: 123,445
  • Since beginning of last month:
    • Site-wide: 111,861

The interplay between host genetics and the gut microbiome reveals common and distinct microbiome features for human complex diseases

microbiology more details view paper
  • Downloaded 639 times
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    • Site-wide: 39,160
    • In microbiology: 2,366
  • Year to date:
    • Site-wide: 73,571
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    • Site-wide: 68,989

Promoter-anchored chromatin interactions predicted from genetic analysis of epigenomic data

genetics more details view paper
  • Downloaded 581 times
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    • Site-wide: 44,121
    • In genetics: 2,067
  • Year to date:
    • Site-wide: 106,652
  • Since beginning of last month:
    • Site-wide: 106,792

Across-cohort QC analyses of genome-wide association study summary statistics from complex traits

genetics more details view paper
  • Downloaded 574 times
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    • Site-wide: 44,723
    • In genetics: 2,094
  • Year to date:
    • Site-wide: 112,241
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    • Site-wide: 87,053

Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals

genetics more details view paper
  • Downloaded 572 times
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    • Site-wide: 44,904
    • In genetics: 2,108
  • Year to date:
    • Site-wide: 13,186
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    • Site-wide: 10,922

Xist Intron 1 Repression by TALE Transcriptional Factor Improves Somatic Cell Reprogamming in Mice

developmental biology more details view paper
  • Downloaded 543 times
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    • Site-wide: 47,924
    • In developmental biology: 1,124
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    • Site-wide: 83,785
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    • Site-wide: 105,376

Genetic analyses of medication-use and implications for precision medicine

genetics more details view paper
  • Downloaded 542 times
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    • Site-wide: 48,030
    • In genetics: 2,255
  • Year to date:
    • Site-wide: 61,309
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    • Site-wide: 61,920

The effect of X-linked dosage compensation on complex trait variation

genetics more details view paper
  • Downloaded 530 times
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    • Site-wide: 49,332
    • In genetics: 2,304
  • Year to date:
    • Site-wide: 123,941
  • Since beginning of last month:
    • Site-wide: 90,865

The Parkinsons Disease Mendelian Randomization Research Portal

neuroscience more details view paper
  • Downloaded 508 times
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    • Site-wide: 51,852
    • In neuroscience: 7,652
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    • Site-wide: 115,263
  • Since beginning of last month:
    • Site-wide: 130,706

Evolution in Sinocyclocheilus cavefish is marked by rate shifts, reversals and origin of novel traits

evolutionary biology more details view paper
  • Downloaded 491 times
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    • Site-wide: 53,902
    • In evolutionary biology: 2,928
  • Year to date:
    • Site-wide: 55,268
  • Since beginning of last month:
    • Site-wide: 58,479

Towards the identification of causal genes for age-related macular degeneration

genetics more details view paper
  • Downloaded 463 times
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    • Site-wide: 57,504
    • In genetics: 2,676
  • Year to date:
    • Site-wide: 89,300
  • Since beginning of last month:
    • Site-wide: 114,735

A pattern categorization of CT findings to predict outcome of COVID-19 pneumonia

infectious diseases more details view paper
  • Downloaded 438 times
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    • Site-wide: 61,004
    • In infectious diseases: 2,914
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    • Site-wide: 73,417
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    • Site-wide: 69,805

Exploring morphological motifs for a single neuron based on multiple 3D reconstructions

bioinformatics more details view paper
  • Downloaded 420 times
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    • Site-wide: 63,627
    • In bioinformatics: 6,230
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    • Site-wide: 74,895
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    • Site-wide: 43,289

Synthesis-Free PET Imaging Of Brown Adipose Tissue And TSPO Via Combination Of Disulfiram And 64CuCl2

pharmacology and toxicology more details view paper
  • Downloaded 411 times
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    • Site-wide: 64,973
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    • Site-wide: 104,161
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    • Site-wide: 90,436

DAZL is a master translational regulator of murine spermatogenesis

developmental biology more details view paper
  • Downloaded 408 times
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    • Site-wide: 65,485
    • In developmental biology: 1,663
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    • Site-wide: 72,504
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    • Site-wide: 78,361

Partitioning Phenotypic Variance Due To Parent-Of-Origin Effects Using Genomic Relatedness Matrices

genetics more details view paper
  • Downloaded 363 times
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    • Site-wide: 72,978
    • In genetics: 3,330
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    • Site-wide: 126,132
  • Since beginning of last month:
    • Site-wide: 121,225

Differences of clinical and imaging findings in multiple generations of secondary COVID-19 infection in Xi'an, China

radiology and imaging more details view paper
  • Downloaded 275 times
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    • Site-wide: 90,520
    • In radiology and imaging: 148
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    • Site-wide: 116,688
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    • Site-wide: 102,149

The role of glycaemic, lipid, blood pressure and obesity risk factors as mediators of the effect of height on Coronary Artery Disease and Type 2 Diabetes Mellitus: A Mendelian Randomisation Study.

genetics more details view paper
  • Downloaded 274 times
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    • Site-wide: 90,759
    • In genetics: 4,095
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    • Site-wide: 128,301
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    • Site-wide: 114,381

Efficacy and Acceptability Comparisons of Cognitive Behavior Therapy, Drugs, and Their Combination for Panic Disorder in Adults: a Network Meta-analysis

psychiatry and clinical psychology more details view paper
  • Downloaded 246 times
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    • Site-wide: 97,012
    • In psychiatry and clinical psychology: 363
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A parsimonious model for mass-univariate vertex-wise analysis

neuroscience more details view paper
  • Downloaded 240 times
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    • Site-wide: 98,198
    • In neuroscience: 15,263
  • Year to date:
    • Site-wide: 8,566
  • Since beginning of last month:
    • Site-wide: 14,964

Cross-Species Integration of Transcriptomic Effects of Tobacco and Nicotine Exposure Helps to Prioritize Genetic Effects on Human Tobacco Consumption

genetics more details view paper
  • Downloaded 186 times
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    • Site-wide: 110,312
    • In genetics: 4,810
  • Year to date:
    • Site-wide: 116,342
  • Since beginning of last month:
    • Site-wide: 115,348

Characterization and expression QTL analysis of TaABI4, a pre-harvest sprouting related gene in wheat

genetics more details view paper
  • Downloaded 157 times
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    • Site-wide: 116,410
    • In genetics: 5,015
  • Year to date:
    • Site-wide: 56,434
  • Since beginning of last month:
    • Site-wide: 83,712

Circuit-free, optoelectronic sensing of electrodermal activities based on photon recycling of a micro-LED

bioengineering more details view paper
  • Downloaded 138 times
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    • Site-wide: 120,212
    • In bioengineering: 2,403
  • Year to date:
    • Site-wide: 91,900
  • Since beginning of last month:
    • Site-wide: 116,091

Once delayed non-invasive remote ischemic preconditioning protects against early stroke by modulating  neuroinflammatory responses in rats

neuroscience more details view paper
  • Downloaded 67 times
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    • Site-wide: 132,160
    • In neuroscience: 20,211
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    • Site-wide: 133,624
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    • Site-wide: 132,751

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