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Author: Jian Yang

Rankings

  • All-time downloads: 131,468 (rank: 585 )
  • Categories:
    • bioengineering: 124 (rank: 13,228 (tie) )
    • bioinformatics: 6,123 (rank: 1,634 )
    • developmental biology: 6,373 (rank: 115 )
    • evolutionary biology: 463 (rank: 13,336 (tie) )
    • genetic and genomic medicine: 1,490 (rank: 942 (tie) )
    • genetics: 95,817 (rank: 17 )
    • genomics: 17,410 (rank: 630 )
    • infectious diseases: 414 (rank: 26,246 (tie) )
    • microbiology: 613 (rank: 19,835 (tie) )
    • neuroscience: 561 (rank: 35,825 (tie) )
    • pharmacology and toxicology: 395 (rank: 3,009 (tie) )
    • psychiatry and clinical psychology: 222 (rank: 3,119 (tie) )
    • radiology and imaging: 1,463 (rank: 172 (tie) )

Downloads per author, site-wide

Preprints

A parsimonious model for mass-univariate vertex-wise analysis

neuroscience more details view paper

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Recovery of trait heritability from whole genome sequence data

genetics more details view paper
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    • Site-wide: 602
    • In genetics: 16
  • Year to date:
    • Site-wide: 4,080
  • Since beginning of last month:
    • Site-wide: 2,518

Expanding Parkinson's disease genetics: novel risk loci, genomic context, causal insights and heritable risk.

genetics more details view paper
  • Downloaded 10,425 times
  • Download rankings, all-time:
    • Site-wide: 666
    • In genetics: 20
  • Year to date:
    • Site-wide: 4,460
  • Since beginning of last month:
    • Site-wide: 2,843

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

genetics more details view paper
  • Downloaded 9,323 times
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    • Site-wide: 761
    • In genetics: 24
  • Year to date:
    • Site-wide: 29,390
  • Since beginning of last month:
    • Site-wide: 23,263

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

genomics more details view paper
  • Downloaded 9,239 times
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    • Site-wide: 777
    • In genomics: 67
  • Year to date:
    • Site-wide: 2,097
  • Since beginning of last month:
    • Site-wide: 1,965

Genetic Consequences of Social Stratification in Great Britain

genetics more details view paper
  • Downloaded 7,572 times
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    • Site-wide: 1,015
    • In genetics: 34
  • Year to date:
    • Site-wide: 8,051
  • Since beginning of last month:
    • Site-wide: 8,783

LD Score Regression Distinguishes Confounding from Polygenicity in Genome-Wide Association Studies

genomics more details view paper
  • Downloaded 7,142 times
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    • Site-wide: 1,093
    • In genomics: 113
  • Year to date:
    • Site-wide: 85,794
  • Since beginning of last month:
    • Site-wide: 35,278

Meta-analysis of genome-wide association studies for height and body mass index in ~700,000 individuals of European ancestry

genetics more details view paper
  • Downloaded 6,497 times
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    • Site-wide: 1,216
    • In genetics: 44
  • Year to date:
    • Site-wide: 37,336
  • Since beginning of last month:
    • Site-wide: 16,737

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

genetics more details view paper
  • Downloaded 3,468 times
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    • Site-wide: 2,969
    • In genetics: 124
  • Year to date:
    • Site-wide: 37,324
  • Since beginning of last month:
    • Site-wide: 23,754

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

bioinformatics more details view paper
  • Downloaded 3,354 times
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    • Site-wide: 3,115
    • In bioinformatics: 336
  • Year to date:
    • Site-wide: 47,056
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    • Site-wide: 76,399

Haplotypes of common SNPs can explain missing heritability of complex diseases

genetics more details view paper
  • Downloaded 3,053 times
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    • Site-wide: 3,580
    • In genetics: 163
  • Year to date:
    • Site-wide: 119,522
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    • Site-wide: 97,005

Commentary on "Limitations of GCTA as a solution to the missing heritability problem"

genetics more details view paper
  • Downloaded 2,856 times
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    • Site-wide: 3,897
    • In genetics: 182
  • Year to date:
    • Site-wide: 52,748
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    • Site-wide: 20,634

Human Naïve Epiblast Cells Possess Unrestricted Lineage Potential

developmental biology more details view paper
  • Downloaded 2,842 times
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    • Site-wide: 3,929
    • In developmental biology: 39
  • Year to date:
    • Site-wide: 2,728
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    • Site-wide: 1,573

Improved polygenic prediction by Bayesian multiple regression on summary statistics

genetics more details view paper
  • Downloaded 2,745 times
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    • Site-wide: 4,125
    • In genetics: 194
  • Year to date:
    • Site-wide: 53,300
  • Since beginning of last month:
    • Site-wide: 40,830

A resource-efficient tool for mixed model association analysis of large-scale data

genetics more details view paper
  • Downloaded 2,609 times
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    • Site-wide: 4,468
    • In genetics: 215
  • Year to date:
    • Site-wide: 15,656
  • Since beginning of last month:
    • Site-wide: 12,980

Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits.

genetics more details view paper
  • Downloaded 2,606 times
  • Download rankings, all-time:
    • Site-wide: 4,479
    • In genetics: 216
  • Year to date:
    • Site-wide: 106,319
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    • Site-wide: 73,700

Widespread signatures of negative selection in the genetic architecture of human complex traits

genetics more details view paper
  • Downloaded 2,191 times
  • Download rankings, all-time:
    • Site-wide: 5,803
    • In genetics: 287
  • Year to date:
    • Site-wide: 117,377
  • Since beginning of last month:
    • Site-wide: 120,705

Genomic evaluation of circulating proteins for drug target characterisation and precision medicine

genetics more details view paper
  • Downloaded 2,079 times
  • Download rankings, all-time:
    • Site-wide: 6,235
    • In genetics: 311
  • Year to date:
    • Site-wide: 8,218
  • Since beginning of last month:
    • Site-wide: 7,503

GWAS on family history of Alzheimer's disease

genetics more details view paper
  • Downloaded 1,953 times
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    • Site-wide: 6,850
    • In genetics: 343
  • Year to date:
    • Site-wide: 114,343
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    • Site-wide: 109,322

Causal associations between risk factors and common diseases inferred from GWAS summary data

genetics more details view paper
  • Downloaded 1,760 times
  • Download rankings, all-time:
    • Site-wide: 7,961
    • In genetics: 395
  • Year to date:
    • Site-wide: 55,130
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    • Site-wide: 60,053

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

genetics more details view paper
  • Downloaded 1,684 times
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    • Site-wide: 8,560
    • In genetics: 435
  • Year to date:
    • Site-wide: 106,575
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    • Site-wide: 63,504

Establishment In Culture Of Expanded Potential Stem Cells

developmental biology more details view paper
  • Downloaded 1,682 times
  • Download rankings, all-time:
    • Site-wide: 8,573
    • In developmental biology: 111
  • Year to date:
    • Site-wide: 97,795
  • Since beginning of last month:
    • Site-wide: 30,822

Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry

genetics more details view paper
  • Downloaded 1,573 times
  • Download rankings, all-time:
    • Site-wide: 9,496
    • In genetics: 487
  • Year to date:
    • Site-wide: 63,357
  • Since beginning of last month:
    • Site-wide: 56,992

Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank

genetics more details view paper
  • Downloaded 1,456 times
  • Download rankings, all-time:
    • Site-wide: 10,613
    • In genetics: 537
  • Year to date:
    • Site-wide: 24,285
  • Since beginning of last month:
    • Site-wide: 29,524

Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

genetics more details view paper
  • Downloaded 1,455 times
  • Download rankings, all-time:
    • Site-wide: 10,623
    • In genetics: 540
  • Year to date:
    • Site-wide: 48,422
  • Since beginning of last month:
    • Site-wide: 68,166

Mixed Model with Correction for Case-Control Ascertainment Increases Association Power

genetics more details view paper
  • Downloaded 1,402 times
  • Download rankings, all-time:
    • Site-wide: 11,268
    • In genetics: 573
  • Year to date:
    • Site-wide: 106,096
  • Since beginning of last month:
    • Site-wide: 105,787

Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations

genetics more details view paper
  • Downloaded 1,373 times
  • Download rankings, all-time:
    • Site-wide: 11,618
    • In genetics: 598
  • Year to date:
    • Site-wide: 33,759
  • Since beginning of last month:
    • Site-wide: 28,964

Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

genetics more details view paper
  • Downloaded 1,359 times
  • Download rankings, all-time:
    • Site-wide: 11,780
    • In genetics: 607
  • Year to date:
    • Site-wide: 117,984
  • Since beginning of last month:
    • Site-wide: 20,072

Improved prediction of chronological age from DNA methylation limits it as a biomarker of ageing

bioinformatics more details view paper
  • Downloaded 1,278 times
  • Download rankings, all-time:
    • Site-wide: 12,935
    • In bioinformatics: 1,619
  • Year to date:
    • Site-wide: 43,218
  • Since beginning of last month:
    • Site-wide: 33,801

Imprint of Assortative Mating on the Human Genome

genetics more details view paper
  • Downloaded 1,269 times
  • Download rankings, all-time:
    • Site-wide: 13,084
    • In genetics: 668
  • Year to date:
    • Site-wide: 95,484
  • Since beginning of last month:
    • Site-wide: 116,943

Expectation of the intercept from bivariate LD score regression in the presence of population stratification

genetics more details view paper
  • Downloaded 1,230 times
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    • Site-wide: 13,688
    • In genetics: 710
  • Year to date:
    • Site-wide: 13,517
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    • Site-wide: 23,694

Bayesian analysis of GWAS summary data reveals differential signatures of natural selection across human complex traits and functional genomic categories

genetics more details view paper
  • Downloaded 1,230 times
  • Download rankings, all-time:
    • Site-wide: 13,709
    • In genetics: 706
  • Year to date:
    • Site-wide: 25,184
  • Since beginning of last month:
    • Site-wide: 22,932

Organizing Pneumonia of COVID-19: Time-dependent Evolution and Outcome in CT Findings

radiology and imaging more details view paper
  • Downloaded 1,199 times
  • Download rankings, all-time:
    • Site-wide: 14,249
    • In radiology and imaging: 27
  • Year to date:
    • Site-wide: 23,700
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    • Site-wide: 22,104

Subtle stratification confounds estimates of heritability from rare variants

genetics more details view paper
  • Downloaded 1,131 times
  • Download rankings, all-time:
    • Site-wide: 15,536
    • In genetics: 803
  • Year to date:
    • Site-wide: 96,936
  • Since beginning of last month:
    • Site-wide: 91,003

Narrow-sense heritability estimation of complex traits using identity-by-descent information.

genetics more details view paper
  • Downloaded 1,112 times
  • Download rankings, all-time:
    • Site-wide: 15,954
    • In genetics: 823
  • Year to date:
    • Site-wide: 71,841
  • Since beginning of last month:
    • Site-wide: 69,447

OSCA: a tool for omic-data-based complex trait analysis

bioinformatics more details view paper
  • Downloaded 1,102 times
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    • Site-wide: 16,176
    • In bioinformatics: 2,006
  • Year to date:
    • Site-wide: 81,328
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    • Site-wide: 100,409

Identification of 55,000 Replicated DNA Methylation QTL

genomics more details view paper
  • Downloaded 1,029 times
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    • Site-wide: 17,902
    • In genomics: 1,872
  • Year to date:
    • Site-wide: 54,453
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    • Site-wide: 103,463

Efficient estimation and applications of cross-validated genetic predictions

genetics more details view paper
  • Downloaded 1,006 times
  • Download rankings, all-time:
    • Site-wide: 18,567
    • In genetics: 941
  • Year to date:
    • Site-wide: 23,655
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    • Site-wide: 25,742

Efficient RNA-mediated reprogramming of human somatic cells to naive pluripotency facilitated by tankyrase inhibition

developmental biology more details view paper
  • Downloaded 940 times
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    • Site-wide: 20,446
    • In developmental biology: 383
  • Year to date:
    • Site-wide: 27,638
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    • Site-wide: 29,789

Novel susceptibility loci and genetic regulation mechanisms for type 2 diabetes

genetics more details view paper
  • Downloaded 851 times
  • Download rankings, all-time:
    • Site-wide: 23,610
    • In genetics: 1,185
  • Year to date:
    • Site-wide: 112,495
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    • Site-wide: 91,353

A comprehensive evaluation of polygenic score methods across cohorts in psychiatric disorders

genetic and genomic medicine more details view paper
  • Downloaded 799 times
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    • Site-wide: 25,813
    • In genetic and genomic medicine: 72
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    • Site-wide: 4,824
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    • Site-wide: 4,072

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

genetics more details view paper
  • Downloaded 777 times
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    • Site-wide: 26,833
    • In genetics: 1,353
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    • Site-wide: 111,470
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    • Site-wide: 100,296

Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration.

genetics more details view paper
  • Downloaded 737 times
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    • Site-wide: 28,875
    • In genetics: 1,444
  • Year to date:
    • Site-wide: 112,429
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    • Site-wide: 56,543

Quantifying genetic heterogeneity between continental populations for human height and body mass index

genetics more details view paper
  • Downloaded 707 times
  • Download rankings, all-time:
    • Site-wide: 30,521
    • In genetics: 1,535
  • Year to date:
    • Site-wide: 55,587
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    • Site-wide: 16,172

Genome-wide analyses of behavioural traits biased by misreports and longitudinal changes

genetic and genomic medicine more details view paper
  • Downloaded 691 times
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    • Site-wide: 31,479
    • In genetic and genomic medicine: 84
  • Year to date:
    • Site-wide: 7,508
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    • Site-wide: 49,358

Constraints on eQTL fine mapping in the presence of multi-site local regulation of gene expression

genetics more details view paper
  • Downloaded 642 times
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    • Site-wide: 34,781
    • In genetics: 1,733
  • Year to date:
    • Site-wide: 99,691
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    • Site-wide: 100,364

The interplay between host genetics and the gut microbiome reveals common and distinct microbiome features for human complex diseases

microbiology more details view paper
  • Downloaded 613 times
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    • Site-wide: 36,881
    • In microbiology: 2,227
  • Year to date:
    • Site-wide: 72,141
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    • Site-wide: 49,766

Improved analyses of GWAS summary statistics by reducing data heterogeneity and errors

genetics more details view paper
  • Downloaded 605 times
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    • Site-wide: 37,535
    • In genetics: 1,858
  • Year to date:
    • Site-wide: 35,561
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    • Site-wide: 22,801

Promoter-anchored chromatin interactions predicted from genetic analysis of epigenomic data

genetics more details view paper
  • Downloaded 565 times
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    • Site-wide: 40,869
    • In genetics: 1,991
  • Year to date:
    • Site-wide: 110,362
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    • Site-wide: 98,614

Across-cohort QC analyses of genome-wide association study summary statistics from complex traits

genetics more details view paper
  • Downloaded 558 times
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    • Site-wide: 41,541
    • In genetics: 2,033
  • Year to date:
    • Site-wide: 122,113
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    • Site-wide: 92,686

Xist Intron 1 Repression by TALE Transcriptional Factor Improves Somatic Cell Reprogamming in Mice

developmental biology more details view paper
  • Downloaded 523 times
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    • Site-wide: 44,906
    • In developmental biology: 1,071
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    • Site-wide: 65,944
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    • Site-wide: 75,531

The effect of X-linked dosage compensation on complex trait variation

genetics more details view paper
  • Downloaded 519 times
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    • Site-wide: 45,401
    • In genetics: 2,194
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    • Site-wide: 117,276
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    • Site-wide: 99,384

Genetic analyses of medication-use and implications for precision medicine

genetics more details view paper
  • Downloaded 517 times
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    • Site-wide: 45,588
    • In genetics: 2,205
  • Year to date:
    • Site-wide: 28,000
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    • Site-wide: 105,147

The Parkinsons Disease Mendelian Randomization Research Portal

neuroscience more details view paper
  • Downloaded 500 times
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    • Site-wide: 47,391
    • In neuroscience: 7,061
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    • Site-wide: 64,090
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    • Site-wide: 106,088

Evolution in Sinocyclocheilus cavefish is marked by rate shifts, reversals and origin of novel traits

evolutionary biology more details view paper
  • Downloaded 463 times
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    • Site-wide: 51,740
    • In evolutionary biology: 2,922
  • Year to date:
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    • Site-wide: 25,284

Towards the identification of causal genes for age-related macular degeneration

genetics more details view paper
  • Downloaded 448 times
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    • Site-wide: 53,604
    • In genetics: 2,568
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    • Site-wide: 48,004
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    • Site-wide: 80,996

Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals

genetics more details view paper
  • Downloaded 447 times
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    • Site-wide: 53,788
    • In genetics: 2,586
  • Year to date:
    • Site-wide: 7,354
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    • Site-wide: 8,671

A pattern categorization of CT findings to predict outcome of COVID-19 pneumonia

infectious diseases more details view paper
  • Downloaded 414 times
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    • Site-wide: 58,297
    • In infectious diseases: 2,530
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    • Site-wide: 59,020
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    • Site-wide: 39,209

Synthesis-Free PET Imaging Of Brown Adipose Tissue And TSPO Via Combination Of Disulfiram And 64CuCl2

pharmacology and toxicology more details view paper
  • Downloaded 395 times
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    • Site-wide: 61,066
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Exploring morphological motifs for a single neuron based on multiple 3D reconstructions

bioinformatics more details view paper
  • Downloaded 389 times
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    • Site-wide: 61,995
    • In bioinformatics: 6,139
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DAZL is a master translational regulator of murine spermatogenesis

developmental biology more details view paper
  • Downloaded 386 times
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    • Site-wide: 62,442
    • In developmental biology: 1,606
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    • Site-wide: 40,617
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    • Site-wide: 107,180

Partitioning Phenotypic Variance Due To Parent-Of-Origin Effects Using Genomic Relatedness Matrices

genetics more details view paper
  • Downloaded 356 times
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    • Site-wide: 67,305
    • In genetics: 3,187
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    • Site-wide: 88,264
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    • Site-wide: 118,401

The role of glycaemic, lipid, blood pressure and obesity risk factors as mediators of the effect of height on Coronary Artery Disease and Type 2 Diabetes Mellitus: A Mendelian Randomisation Study.

genetics more details view paper
  • Downloaded 266 times
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    • Site-wide: 84,241
    • In genetics: 3,896
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    • Site-wide: 105,954
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    • Site-wide: 114,827

Differences of clinical and imaging findings in multiple generations of secondary COVID-19 infection in Xi'an, China

radiology and imaging more details view paper
  • Downloaded 264 times
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    • Site-wide: 84,673
    • In radiology and imaging: 130
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    • Site-wide: 93,459
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    • Site-wide: 64,601

Efficacy and Acceptability Comparisons of Cognitive Behavior Therapy, Drugs, and Their Combination for Panic Disorder in Adults: a Network Meta-analysis

psychiatry and clinical psychology more details view paper
  • Downloaded 222 times
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    • Site-wide: 93,531
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    • Site-wide: 78,624

Cross-Species Integration of Transcriptomic Effects of Tobacco and Nicotine Exposure Helps to Prioritize Genetic Effects on Human Tobacco Consumption

genetics more details view paper
  • Downloaded 177 times
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    • Site-wide: 103,006
    • In genetics: 4,647
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    • Site-wide: 71,667
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    • Site-wide: 98,700

Circuit-free, optoelectronic sensing of electrodermal activities based on photon recycling of a micro-LED

bioengineering more details view paper
  • Downloaded 124 times
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    • Site-wide: 112,958
    • In bioengineering: 2,254
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    • Site-wide: 46,507
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Characterization and expression QTL analysis of TaABI4, a pre-harvest sprouting related gene in wheat

genetics more details view paper
  • Downloaded 120 times
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    • Site-wide: 113,623
    • In genetics: 4,993
  • Year to date:
    • Site-wide: 55,715
  • Since beginning of last month:
    • Site-wide: 74,126

Once delayed non-invasive remote ischemic preconditioning protects against early stroke by modulating  neuroinflammatory responses in rats

neuroscience more details view paper
  • Downloaded 61 times
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    • Site-wide: 122,482
    • In neuroscience: 19,070
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