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Author: Shamil Sunyaev

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  • All-time downloads: 11,712 (rank: 6,742 out of 397,875)
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    • bioinformatics: 982 (rank: 11,605 (tie) out of 33,943)
    • evolutionary biology: 2,498 (rank: 1,294 out of 20,386)
    • genetics: 5,628 (rank: 2,982 (tie) out of 36,549)
    • genomics: 2,604 (rank: 7,501 (tie) out of 42,257)

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Preprints

Phenotype-specific information improves prediction of functional impact for noncoding variants

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Quantifying the unobserved protein-coding variants in human populations provides a roadmap for large-scale sequencing projects

genetics more details view paper
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Population-specific causal disease effect sizes in functionally important regions impacted by selection

genetics more details view paper
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Population sequencing data reveal a compendium of mutational processes in human germline

genetics more details view paper
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Low-frequency variant functional architectures reveal strength of negative selection across coding and non-coding annotations

genetics more details view paper
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Genome wide association with quantitative resistance phenotypes in Mycobacterium tuberculosis reveals novel resistance genes and regulatory regions

evolutionary biology more details view paper
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Leveraging distant relatedness to quantify human mutation and gene conversion rates

genetics more details view paper
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Fine-scale haplotype structure reveals strong signatures of positive selection in a recombining bacterial pathogen

evolutionary biology more details view paper
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No evidence that natural selection has been less effective at removing deleterious mutations in Europeans than in West Africans

evolutionary biology more details view paper
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Unexpected variability of allelic imbalance estimates from RNA sequencing

bioinformatics more details view paper
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A literature review at genome scale: improving clinical variant assessment

bioinformatics more details view paper
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Maintenance of adaptive dynamics in a bottlenecked range-edge population that retained outcrossing

evolutionary biology more details view paper
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