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Author: Jacob G. Scott

  • ORCiD: http://orcid.org/0000-0003-2971-7673
  • Most recently observed institution: Translational Hematology Oncology Research, Cleveland Clinic; Case Western Reserve University School of Medicine; Department of Physics, Case Western Reserve University

Rankings

  • All-time downloads: 20,841 (rank: 2,734 out of 394,350)
  • Categories:
    • bioengineering: 900 (rank: 2,308 (tie) out of 11,519)
    • biophysics: 701 (rank: 4,976 (tie) out of 16,344)
    • cancer biology: 9,831 (rank: 136 out of 27,342)
    • evolutionary biology: 6,641 (rank: 288 out of 20,148)
    • systems biology: 2,768 (rank: 959 (tie) out of 11,540)

Downloads per author, site-wide

Preprints

Fibroblasts and Alectinib switch the evolutionary games played by non-small cell lung cancer

cancer biology more details view paper
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Antibiotic collateral sensitivity is contingent on the repeatability of evolution

evolutionary biology more details view paper
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    • In evolutionary biology: 254 out of 5,599
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egtplot: A Python Package for 3-Strategy Evolutionary Games

evolutionary biology more details view paper
  • Downloaded 1,497 times
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    • In evolutionary biology: 285 out of 5,599
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Exploiting evolutionary non-commutativity to prevent the emergence of bacterial antibiotic resistance

evolutionary biology more details view paper
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    • In evolutionary biology: 304 out of 5,599
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MultiCellDS: a community-developed standard for curating microenvironment-dependent multicellular data

systems biology more details view paper
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    • In systems biology: 265 out of 2,365
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    • Site-wide: 24,665 out of 92,316

Recasting the cancer stem cell hypothesis: unification using a continuum model of microenvironmental forces

cancer biology more details view paper
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    • In cancer biology: 348 out of 3,262
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A Low-Cost, Open Source, Self-Contained Bacterial EVolutionary biorEactor (EVE)

bioengineering more details view paper
  • Downloaded 900 times
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    • In bioengineering: 273 out of 2,090
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    • Site-wide: 9,629 out of 92,316

Optimal Therapy Scheduling Based on a Pair of Collaterally Sensitive Drugs

cancer biology more details view paper
  • Downloaded 861 times
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    • In cancer biology: 432 out of 3,262
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Passenger DNA alterations reduce cancer fitness in cell culture and mouse models

cancer biology more details view paper
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    • In cancer biology: 436 out of 3,262
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    • Site-wide: 73,861 out of 92,316

Controlling the speed and trajectory of evolution with counterdiabatic driving

evolutionary biology more details view paper
  • Downloaded 836 times
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    • Site-wide: 15,779 out of 92,316
    • In evolutionary biology: 961 out of 5,599
  • Year to date:
    • Site-wide: 6,942 out of 92,316
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    • Site-wide: 5,684 out of 92,316

Endogenous miRNA sponges mediate the generation of oscillatory dynamics for a non-coding RNA network

systems biology more details view paper
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    • Site-wide: 20,257 out of 92,316
    • In systems biology: 561 out of 2,365
  • Year to date:
    • Site-wide: 41,000 out of 92,316
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    • Site-wide: 65,015 out of 92,316

Temporally feathered intensity modulated radiation therapy: a planning technique to reduce normal tissue toxicity

biophysics more details view paper
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    • In biophysics: 723 out of 4,010
  • Year to date:
    • Site-wide: 49,100 out of 92,316
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    • Site-wide: 50,199 out of 92,316

Estimating stem cell fractions in hierarchically organized tumors

cancer biology more details view paper
  • Downloaded 684 times
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    • Site-wide: 21,361 out of 92,316
    • In cancer biology: 658 out of 3,262
  • Year to date:
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    • Site-wide: 59,331 out of 92,316

Collateral sensitivity networks reveal evolutionary instability and novel treatment strategies in ALK mutated non-small cell lung cancer.

cancer biology more details view paper
  • Downloaded 684 times
  • Download rankings, all-time:
    • Site-wide: 21,360 out of 92,316
    • In cancer biology: 655 out of 3,262
  • Year to date:
    • Site-wide: 72,059 out of 92,316
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    • Site-wide: 59,284 out of 92,316

Inferring Tumour Proliferative Organisation from Phylogenetic Tree Measures in a Computational Model

cancer biology more details view paper
  • Downloaded 672 times
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    • Site-wide: 21,903 out of 92,316
    • In cancer biology: 671 out of 3,262
  • Year to date:
    • Site-wide: 52,177 out of 92,316
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    • Site-wide: 52,611 out of 92,316

MultiCellDS: a standard and a community for sharing multicellular data

systems biology more details view paper
  • Downloaded 662 times
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    • Site-wide: 22,438 out of 92,316
    • In systems biology: 634 out of 2,365
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    • Site-wide: 76,961 out of 92,316

Optimizing adaptive cancer therapy: dynamic programming and evolutionary game theory

cancer biology more details view paper
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    • In cancer biology: 690 out of 3,262
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Microenvironmental variables must influence intrinsic phenotypic parameters of cancer stem cells to affect tumourigenicity

cancer biology more details view paper
  • Downloaded 598 times
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    • Site-wide: 25,867 out of 92,316
    • In cancer biology: 820 out of 3,262
  • Year to date:
    • Site-wide: 80,943 out of 92,316
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    • Site-wide: 66,392 out of 92,316

Cancer treatment scheduling and dynamic heterogeneity in social dilemmas of tumour acidity and vasculature

cancer biology more details view paper
  • Downloaded 593 times
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    • Site-wide: 26,153 out of 92,316
    • In cancer biology: 828 out of 3,262
  • Year to date:
    • Site-wide: 78,261 out of 92,316
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    • Site-wide: 59,286 out of 92,316

Takeover times for a simple model of network infection

evolutionary biology more details view paper
  • Downloaded 545 times
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    • Site-wide: 29,101 out of 92,316
    • In evolutionary biology: 1,927 out of 5,599
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    • Site-wide: 76,044 out of 92,316

Hypoxia increases the tempo of evolution in glioblastoma

cancer biology more details view paper
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    • In cancer biology: 980 out of 3,262
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    • Site-wide: 47,331 out of 92,316

Harnessing the lymphocyte meta-phenotype to optimize adoptive cell therapy

cancer biology more details view paper
  • Downloaded 419 times
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    • In cancer biology: 1,278 out of 3,262
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    • Site-wide: 59,274 out of 92,316

Edge effects in game theoretic dynamics of spatially structured tumours

cancer biology more details view paper
  • Downloaded 411 times
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    • Site-wide: 40,762 out of 92,316
    • In cancer biology: 1,303 out of 3,262
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    • Site-wide: 66,378 out of 92,316

Range expansion shifts clonal interference patterns in evolving populations

evolutionary biology more details view paper
  • Downloaded 378 times
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    • In evolutionary biology: 3,039 out of 5,599
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    • Site-wide: 24,784 out of 92,316

Identifying states of collateral sensitivity during the evolution of therapeutic resistance in Ewing’s sarcoma

evolutionary biology more details view paper
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    • Site-wide: 51,193 out of 92,316
    • In evolutionary biology: 3,480 out of 5,599
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    • Site-wide: 19,097 out of 92,316

Network potential identifies therapeutic miRNA cocktails in Ewing sarcoma

systems biology more details view paper
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    • In systems biology: 1,697 out of 2,365
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    • Site-wide: 55,684 out of 92,316

Modeling collaterally sensitive drug cycles: shaping heterogeneity to allow adaptive therapy

cancer biology more details view paper
  • Downloaded 140 times
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    • Site-wide: 80,967 out of 92,316
    • In cancer biology: 2,775 out of 3,262
  • Year to date:
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  • Since beginning of last month:
    • Site-wide: 1,716 out of 92,316

Impact of immediate cryopreservation on the establishment of patient derived xenografts from head and neck cancer patients.

cancer biology more details view paper
  • Downloaded 99 times
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    • Site-wide: 85,632 out of 92,316
    • In cancer biology: 2,982 out of 3,262
  • Year to date:
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  • Since beginning of last month:
    • Site-wide: 49,857 out of 92,316

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