Author: Harold Snieder

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Preprints

Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus.

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Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

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Genomic analysis of diet composition finds novel loci and associations with health and lifestyle

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Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

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Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

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Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

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Mega-analysis of 31,396 individuals from 6 countries uncovers strong gene-environment interaction for human fertility

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The genetic architecture of sporadic and recurrent miscarriage

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Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: Findings from the Pregnancy and Childhood Epigenetics (PACE) consortium.

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Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

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Trans-ethnic genome-wide association study provides insight into effector genes and molecular mechanisms for kidney function and highlights a causal effect on kidney-specific disease aetiologies

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Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo image- and CRISPR/Cas9/based approach

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Genetic Association Study of Childhood Aggression across raters, instruments and age

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Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

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Discovering patterns of pleiotropy in genome-wide association studies

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Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

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Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

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Identification of 370 loci for age at onset of sexual and reproductive behaviour, highlighting common aetiology with reproductive biology, externalizing behaviour and longevity

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Maternal alcohol consumption during pregnancy and offspring epigenome-wide DNA methylation: findings from six general population-based birth cohorts

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Kidney Function and Blood Pressure: A Bi-directional Mendelian Randomisation Study

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KCND3 is a novel susceptibility locus for early repolarization

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