Author: Peter Kraft

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Preprints

Genome-wide association study identifies 48 common genetic variants associated with handedness

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  • Site-wide: 4,949
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  • Site-wide: 17,373
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  • Site-wide: 18,077

Improving reporting standards for polygenic scores in risk prediction studies

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  • Site-wide: 8,398
  • In genetic and genomic medicine: 24
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  • Site-wide: 3,515
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  • Site-wide: 4,408

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

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  • Site-wide: 8,899
  • In genetics: 440
• Year to date:
  • Site-wide: 57,604
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  • Site-wide: 55,079

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

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  • Site-wide: 9,281
  • In genetics: 457
• Year to date:
  • Site-wide: 45,984
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  • Site-wide: 56,628

Transcriptome-wide association studies accounting for colocalization using Egger regression

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  • Site-wide: 12,110
  • In epidemiology: 825
• Year to date:
  • Site-wide: 80,181
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  • Site-wide: 80,118

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

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  • Site-wide: 14,271
  • In genomics: 1,515
• Year to date:
  • Site-wide: 57,338
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  • Site-wide: 46,533

Improved methods for multi-trait fine mapping of pleiotropic risk loci

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  • Site-wide: 15,295
  • In genetics: 786
• Year to date:
  • Site-wide: 100,569
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  • Site-wide: 98,614

Large-Scale Genome-Wide Meta Analysis of Polycystic Ovary Syndrome Suggests Shared Genetic Architecture for Different Diagnosis Criteria.

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  • Site-wide: 18,217
  • In genetics: 914
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  • Site-wide: 70,039
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  • Site-wide: 39,337

Selection on the FADS region in Europeans

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  • Site-wide: 21,115
  • In genetics: 1,044
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  • Site-wide: 94,225
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  • Site-wide: 87,624

Assessment of Polygenic Architecture and Risk Prediction based on Common Variants Across Fourteen Cancers

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  • Site-wide: 24,011
  • In genetics: 1,193
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  • Site-wide: 29,689

Playing Musical Chairs in Big Data to Reveal Variables Associations

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  • Site-wide: 25,577
  • In genetics: 1,266
• Year to date:
  • Site-wide: 117,346
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  • Site-wide: 100,652

Multitrait genetic-phenotype associations to connect disease variants and biological mechanisms

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  • Site-wide: 25,985
  • In genetics: 1,290
• Year to date:
  • Site-wide: 24,463
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  • Site-wide: 49,537

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

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  • Site-wide: 26,036
  • In genetics: 1,292
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  • Site-wide: 41,538
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  • Site-wide: 46,444

Powerful gene set analysis in GWAS with the Generalized Berk-Jones statistic

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  • Site-wide: 26,760
  • In genetics: 1,336
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Estimating the effective sample size in association studies of quantitative traits

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  • Site-wide: 26,806
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  • Site-wide: 10,885
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  • Site-wide: 10,636

A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma and includes a genetic link with Alzheimer's disease

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  • Site-wide: 27,160
  • In genetics: 1,351
• Year to date:
  • Site-wide: 28,014
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  • Site-wide: None

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

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  • Site-wide: 28,373
  • In genetics: 1,413
• Year to date:
  • Site-wide: 49,154
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  • Site-wide: 53,774

Combining genome-wide studies of breast, prostate, ovarian and endometrial cancers maps cross-cancer susceptibility loci and identifies new genetic associations

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  • Site-wide: 39,802
  • In genetics: 1,928
• Year to date:
  • Site-wide: 22,397
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  • Site-wide: 25,434

Prospective Evaluation of a Breast Cancer Risk Model Integrating Classical Risk Factors and Polygenic Risk in 15 Cohorts from Six Countries

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  • Site-wide: 41,588
  • In epidemiology: 1,944
• Year to date:
  • Site-wide: 64,014
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  • Site-wide: 61,588

Explicit modeling of ancestry improves polygenic risk scores and BLUP prediction

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  • Site-wide: 43,915
  • In genetics: 2,119
• Year to date:
  • Site-wide: 100,293
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  • Site-wide: 98,429

Somatic mutational profiles and germline polygenic risk scores in human cancer

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  • Site-wide: 46,515
  • In genomics: 3,758
• Year to date:
  • Site-wide: 1,191
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  • Site-wide: 487

Shared heritability and functional enrichment across six solid cancers

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  • Site-wide: 46,977
  • In genomics: 3,791
• Year to date:
  • Site-wide: 104,126
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  • Site-wide: 71,315

Genome-wide association study of anti-Mullerian hormone levels in pre-menopausal women of late reproductive age and relationship with genetic determinants of reproductive lifespan

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  • Site-wide: 51,055
  • In genomics: 4,009
• Year to date:
  • Site-wide: 82,890
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  • Site-wide: 68,671

Common breast cancer risk loci predispose to distinct tumor subtypes

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  • Site-wide: 52,070
  • In genetics: 2,483
• Year to date:
  • Site-wide: 13,074
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  • Site-wide: 5,499

A comprehensive survey of genetic variation in 20,691 subjects from four large cohorts

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  • Site-wide: 52,110
  • In epidemiology: 2,269
• Year to date:
  • Site-wide: 104,144
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  • Site-wide: None

A prospective analysis of circulating plasma metabolomics and ovarian cancer risk

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  • Site-wide: 52,995
  • In epidemiology: 2,300
• Year to date:
  • Site-wide: 53,571
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  • Site-wide: 45,514

Genetic insights into the biological mechanisms governing human ovarian ageing

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  • Site-wide: 53,406
  • In sexual and reproductive health: 20
• Year to date:
  • Site-wide: 1,414
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  • Site-wide: 1,646

Association between CCR5-Δ32 homozygosity and mortality in 37,650 participants from three U.S.-based cohorts

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  • Site-wide: 54,030
  • In epidemiology: 2,329
• Year to date:
  • Site-wide: 121,726
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  • Site-wide: 89,828

Mixed-model admixture mapping identifies smoking-dependent loci of lung function in African Americans

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  • Site-wide: 74,547
  • In genetics: 3,465
• Year to date:
  • Site-wide: 70,866
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  • Site-wide: 39,794

Genome-wide association study meta-analysis identifies three novel loci for circulating anti-Müllerian hormone levels in women

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  • Site-wide: 81,981
  • In genetic and genomic medicine: 268
• Year to date:
  • Site-wide: 16,518
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  • Site-wide: 16,309

Cross-cancer genome-wide association study of endometrial cancer and epithelial ovarian cancer identifies genetic risk regions associated with risk of both cancers

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  • Site-wide: 84,258
  • In oncology: 129
• Year to date:
  • Site-wide: 58,363
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  • Site-wide: 91,326

Leveraging expression from multiple tissues using sparse canonical correlation analysis (sCCA) and aggregate tests improves the power of transcriptome-wide association studies (TWAS)

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  • Site-wide: 84,377
  • In genetics: 3,879
• Year to date:
  • Site-wide: 23,675
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  • Site-wide: 16,574

Circulating Lysophosphatidylcholines, Phosphatidylcholines, Ceramides, and Sphingomyelins and Ovarian Cancer Risk: a 23-year Prospective Study

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  • Site-wide: 97,493
  • In epidemiology: 3,969
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  • Site-wide: 121,004
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  • Site-wide: 105,580