Author: Tonu Esko

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Preprints

A catalogue of omics biological ageing clocks reveals substantial commonality and associations with disease risk

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Genomewide association study identifies 30 loci associated with bipolar disorder

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Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

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Exome sequencing identifies rare coding variants in 10 genes which confer substantial risk for schizophrenia

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Genome-wide association study identifies 48 common genetic variants associated with handedness

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Human loss-of-function variants suggest that partial LRRK2 inhibition is a safe therapeutic strategy for Parkinson’s disease

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The Polygenic and Monogenic Basis of Blood Traits and Diseases

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Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

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Educational attainment and personality are genetically intertwined

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Genome-wide association study of over 40,000 bipolar disorder cases provides novel biological insights

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Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci

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Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

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Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

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Advantages of genotype imputation with ethnically matched reference panel for rare variant association analyses

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Genome-wide study identifies association between HLA-B*55:01 and penicillin allergy

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Analytical strategies to include the X-chromosome in variance heterogeneity analyses: evidence for trait-specific polygenic variance structure

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Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

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Integrating untargeted metabolomics, genetically informed causal inference, and pathway enrichment to define the obesity metabolome

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Genome-wide analysis of 944,133 individuals provides insights into the etiology of hemorrhoidal disease

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Mendelian randomization identifies the potential causal impact of dietary patterns on circulating blood metabolites

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Genome-wide Screen of Otosclerosis in Population Biobanks: 18 Loci and Shared Heritability with Skeletal Structure

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Mendelian randomization study of spermine oxidase and cancer risk

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