Author: Hae Kyung Im

Downloads per author, site-wide

Preprints

Polygenic transcriptome risk scores improve portability of polygenic risk scores across ancestries

No download data for this paper yet.

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics

• Downloaded 10,856 times
• Download rankings, all-time:
  • Site-wide: 563 out of 118,102
  • In bioinformatics: 26 out of 9,568
• Year to date:
  • Site-wide: 6,122 out of 118,102
• Since beginning of last month:
  • Site-wide: 8,264 out of 118,102

LeafCutter: Annotation-free quantification of RNA splicing

• Downloaded 8,099 times
• Download rankings, all-time:
  • Site-wide: 844 out of 118,102
  • In genomics: 80 out of 6,432
• Year to date:
  • Site-wide: 7,448 out of 118,102
• Since beginning of last month:
  • Site-wide: 13,851 out of 118,102

The GTEx Consortium atlas of genetic regulatory effects across human tissues

• Downloaded 7,681 times
• Download rankings, all-time:
  • Site-wide: 898 out of 118,102
  • In genetics: 30 out of 5,131
• Year to date:
  • Site-wide: 1,291 out of 118,102
• Since beginning of last month:
  • Site-wide: 2,664 out of 118,102

PrediXcan: Trait Mapping Using Human Transcriptome Regulation

• Downloaded 3,814 times
• Download rankings, all-time:
  • Site-wide: 2,345 out of 118,102
  • In genomics: 297 out of 6,432
• Year to date:
  • Site-wide: 26,950 out of 118,102
• Since beginning of last month:
  • Site-wide: 22,597 out of 118,102

Exploiting the GTEx resources to decipher the mechanisms at GWAS loci

• Downloaded 2,943 times
• Download rankings, all-time:
  • Site-wide: 3,423 out of 118,102
  • In genetics: 168 out of 5,131
• Year to date:
  • Site-wide: 2,739 out of 118,102
• Since beginning of last month:
  • Site-wide: 2,579 out of 118,102

Diverse transcriptomic signatures across human tissues identify functional rare genetic variation

• Downloaded 1,790 times
• Download rankings, all-time:
  • Site-wide: 7,102 out of 118,102
  • In genomics: 831 out of 6,432
• Year to date:
  • Site-wide: 7,111 out of 118,102
• Since beginning of last month:
  • Site-wide: 29,632 out of 118,102

Survey of the Heritability and Sparsity of Gene Expression Traits Across Human Tissues

• Downloaded 1,640 times
• Download rankings, all-time:
  • Site-wide: 8,106 out of 118,102
  • In genomics: 964 out of 6,432
• Year to date:
  • Site-wide: 72,646 out of 118,102
• Since beginning of last month:
  • Site-wide: 63,341 out of 118,102

PhenomeXcan: Mapping the genome to the phenome through the transcriptome

• Downloaded 1,533 times
• Download rankings, all-time:
  • Site-wide: 8,987 out of 118,102
  • In genetics: 476 out of 5,131
• Year to date:
  • Site-wide: 6,818 out of 118,102
• Since beginning of last month:
  • Site-wide: 22,832 out of 118,102

Integrative cross tissue analysis of gene expression identifies novel type 2 diabetes genes

• Downloaded 1,362 times
• Download rankings, all-time:
  • Site-wide: 10,749 out of 118,102
  • In genetics: 564 out of 5,131
• Year to date:
  • Site-wide: 50,853 out of 118,102
• Since beginning of last month:
  • Site-wide: 44,252 out of 118,102

Mechanisms of tissue-specific genetic regulation revealed by latent factors across eQTLs

• Downloaded 1,312 times
• Download rankings, all-time:
  • Site-wide: 11,346 out of 118,102
  • In genomics: 1,304 out of 6,432
• Year to date:
  • Site-wide: 9,768 out of 118,102
• Since beginning of last month:
  • Site-wide: 46,399 out of 118,102

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

• Downloaded 1,207 times
• Download rankings, all-time:
  • Site-wide: 12,857 out of 118,102
  • In genomics: 1,445 out of 6,432
• Year to date:
  • Site-wide: 86,893 out of 118,102
• Since beginning of last month:
  • Site-wide: 63,371 out of 118,102

Genetic architecture of gene expression traits across diverse populations

• Downloaded 1,176 times
• Download rankings, all-time:
  • Site-wide: 13,368 out of 118,102
  • In genomics: 1,487 out of 6,432
• Year to date:
  • Site-wide: 59,323 out of 118,102
• Since beginning of last month:
  • Site-wide: 63,354 out of 118,102

Gene expression imputation across multiple brain regions reveals schizophrenia risk throughout development.

• Downloaded 1,090 times
• Download rankings, all-time:
  • Site-wide: 14,956 out of 118,102
  • In genetics: 795 out of 5,131
• Year to date:
  • Site-wide: 62,001 out of 118,102
• Since beginning of last month:
  • Site-wide: 86,072 out of 118,102

Shared and Distinct Genetic Risk Factors for Childhood Onset and Adult Onset Asthma: Genome- and Transcriptome-wide Studies

• Downloaded 1,001 times
• Download rankings, all-time:
  • Site-wide: 16,989 out of 118,102
  • In genetics: 892 out of 5,131
• Year to date:
  • Site-wide: 40,088 out of 118,102
• Since beginning of last month:
  • Site-wide: 44,601 out of 118,102

Integrating Predicted Transcriptome From Multiple Tissues Improves Association Detection

• Downloaded 952 times
• Download rankings, all-time:
  • Site-wide: 18,329 out of 118,102
  • In genomics: 1,944 out of 6,432
• Year to date:
  • Site-wide: None out of 118,102
• Since beginning of last month:
  • Site-wide: None out of 118,102

Transcriptomic Imputation of Bipolar Disorder and Bipolar subtypes reveals 29 novel associated genes

• Downloaded 885 times
• Download rankings, all-time:
  • Site-wide: 20,319 out of 118,102
  • In genetics: 1,048 out of 5,131
• Year to date:
  • Site-wide: 51,980 out of 118,102
• Since beginning of last month:
  • Site-wide: 42,492 out of 118,102

Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx

• Downloaded 805 times
• Download rankings, all-time:
  • Site-wide: 23,334 out of 118,102
  • In genetics: 1,210 out of 5,131
• Year to date:
  • Site-wide: 12,368 out of 118,102
• Since beginning of last month:
  • Site-wide: 73,699 out of 118,102

Identifying tissues implicated in Anorexia Nervosa using Transcriptomic Imputation

• Downloaded 781 times
• Download rankings, all-time:
  • Site-wide: 24,299 out of 118,102
  • In genetics: 1,264 out of 5,131
• Year to date:
  • Site-wide: 54,316 out of 118,102
• Since beginning of last month:
  • Site-wide: 31,523 out of 118,102

Imputed gene associations identify replicable trans-acting genes enriched in transcription pathways and complex traits

• Downloaded 700 times
• Download rankings, all-time:
  • Site-wide: 28,316 out of 118,102
  • In genetics: 1,469 out of 5,131
• Year to date:
  • Site-wide: 80,444 out of 118,102
• Since beginning of last month:
  • Site-wide: 63,210 out of 118,102

Analysis of Genetically Regulated Gene Expression identifies a trauma type specific PTSD gene, SNRNP35

• Downloaded 591 times
• Download rankings, all-time:
  • Site-wide: 35,318 out of 118,102
  • In genetics: 1,796 out of 5,131
• Year to date:
  • Site-wide: 73,075 out of 118,102
• Since beginning of last month:
  • Site-wide: 71,288 out of 118,102

Multiethnic Meta-analysis Identifies New Loci for Pulmonary Function

• Downloaded 585 times
• Download rankings, all-time:
  • Site-wide: 35,751 out of 118,102
  • In genetics: 1,814 out of 5,131
• Year to date:
  • Site-wide: 98,870 out of 118,102
• Since beginning of last month:
  • Site-wide: 95,167 out of 118,102

Fine-mapping and QTL tissue-sharing information improve causal gene identification and transcriptome prediction performance

• Downloaded 554 times
• Download rankings, all-time:
  • Site-wide: 38,267 out of 118,102
  • In genomics: 3,262 out of 6,432
• Year to date:
  • Site-wide: 12,199 out of 118,102
• Since beginning of last month:
  • Site-wide: 13,869 out of 118,102

Scalable unified framework of total and allele-specific counts for cis-QTL, fine-mapping, and prediction

• Downloaded 480 times
• Download rankings, all-time:
  • Site-wide: 45,406 out of 118,102
  • In genomics: 3,719 out of 6,432
• Year to date:
  • Site-wide: 14,697 out of 118,102
• Since beginning of last month:
  • Site-wide: 30,565 out of 118,102

CORE GREML: Estimating covariance between random effects in linear mixed models for genomic analyses of complex traits

• Downloaded 372 times
• Download rankings, all-time:
  • Site-wide: 59,179 out of 118,102
  • In genetics: 2,896 out of 5,131
• Year to date:
  • Site-wide: 47,139 out of 118,102
• Since beginning of last month:
  • Site-wide: 81,963 out of 118,102

Probabilistic Colocalization of Genetic Variants from Complex and Molecular Traits: Promise and Limitations

• Downloaded 294 times
• Download rankings, all-time:
  • Site-wide: 72,101 out of 118,102
  • In genetics: 3,467 out of 5,131
• Year to date:
  • Site-wide: 26,849 out of 118,102
• Since beginning of last month:
  • Site-wide: 35,633 out of 118,102