Author: Archie Campbell

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Preprints

Genetic insights into the biological mechanisms governing human ovarian ageing

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The genetic structure of the world's first farmers

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  • Site-wide: 1,687

Clinical classifiers of COVID-19 infection from novel ultra-high-throughput proteomics

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  • Site-wide: 1,532
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A time-resolved proteomic and diagnostic map characterizes COVID-19 disease progression and predicts outcome

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  • Site-wide: 1,540
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Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

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  • Site-wide: 3,581
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Mental health during the COVID-19 pandemic in two longitudinal UK population cohorts

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  • Site-wide: 5,853
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Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112,117).

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Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

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Genetic stratification of depression in UK Biobank suggests a subgroup linked to age of natural menopause

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Epigenetic prediction of complex traits and death

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  • Site-wide: 55,783
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  • Site-wide: 120,298

Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibility

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  • Site-wide: 19,543
  • In genetic and genomic medicine: 54
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  • Site-wide: 11,057
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  • Site-wide: 8,125

Genome-wide Meta-analysis of 158,000 Individuals of European Ancestry Identifies Three Loci Associated with Chronic Back Pain

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  • Site-wide: 91,839
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Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

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  • Site-wide: 26,090
  • In genetics: 1,319
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Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

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Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

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Quantifying the extent to which index event biases influence large genetic association studies

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The Trans-Ancestral Genomic Architecture of Glycaemic Traits

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Epigenetic clocks predict prevalence and incidence of leading causes of death and disease burden

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  • In genomics: 2,962
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Electronic Health Record and Genome-wide Genetic Data in Generation Scotland Participants

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  • Site-wide: 42,615
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  • Site-wide: 54,846

A meta-analysis of genome-wide association studies of epigenetic age acceleration

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  • Site-wide: 40,927
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  • Site-wide: 101,936
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  • Site-wide: 108,290

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

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  • Site-wide: 41,335
  • In genetics: 2,023
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  • Site-wide: 79,588

DNA methylation age acceleration and risk factors for Alzheimer's disease

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  • In genomics: 3,465
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  • Site-wide: 114,068
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  • Site-wide: 92,196

VEP-G2P: A Tool for Efficient, Flexible and Scalable Diagnostic Filtering of Genomic Variants

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Insight into the genetic aetiology of retinal detachment by combining small clinical and large population-based datasets

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An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort 1936.

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  • Site-wide: 49,249
  • In epidemiology: 2,131
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  • Site-wide: 85,774
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  • Site-wide: 90,221

Meta-analysis of exome array data identifies six novel genetic loci for lung function

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  • Site-wide: 51,158
  • In genetics: 2,468
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  • Site-wide: 68,286
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  • Site-wide: 112,979

Birth weight associations with psychiatric and physical health, cognitive function, and DNA methylation differences in an adult population

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  • Site-wide: 57,661
  • In genomics: 4,336
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  • Site-wide: 79,494

Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism

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  • Site-wide: 59,020
  • In genetics: 2,834
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  • Site-wide: 99,775

Characterisation of an inflammation-related epigenetic score and its association with cognitive ability

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  • Site-wide: 62,367
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  • Site-wide: 73,231

Face covering adherence is positively associated with better mental health and wellbeing: a longitudinal analysis of the CovidLife surveys

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  • Site-wide: 64,423
  • In psychiatry and clinical psychology: 188
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  • Site-wide: 1,470

Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

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  • In genetics: 3,301
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  • Site-wide: 87,490
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  • Site-wide: 111,237

Epigenome-wide analyses identify DNA methylation signatures of dementia risk

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  • Site-wide: 72,037
  • In genetic and genomic medicine: 206
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  • Site-wide: 30,978

Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2

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An epigenome-wide association study of sex-specific chronological ageing

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  • In genomics: 5,014
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  • Site-wide: 109,661

Epigenetic signatures of starting and stopping smoking

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  • Site-wide: 81,124
  • In genomics: 5,295
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  • Site-wide: 111,206
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  • Site-wide: 94,136

Shared genetics and couple-associated environment are major contributors to the risk of both clinical and self-declared depression

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Assessment of Dried Blood Spots for DNA Methylation Profiling

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  • Site-wide: 120,303

Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD

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  • Site-wide: 108,093

DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

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Creating and validating a DNA methylation-based proxy for Interleukin-6

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DNA methylation in the APOE gene: its link with Alzheimer's and cardiovascular health

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  • Site-wide: 96,862
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  • Site-wide: 77,131

Using human genetics to understand the causes and consequences of circulating cardiac troponin I in the general population

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Subthreshold psychosis symptoms associated with molecular genetic risk in a population-based cohort: Findings from Generation Scotland

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DNA methylation signatures of C-reactive protein associations with structural neuroimaging measures and major depressive disorder

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DNA methylation proxies for 16 plasma proteins predict the incidence of 7 leading causes of morbidity

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Omics versus Questionnaires: Using methylation data to assess the environmental impact of smoking on obesity-related traits

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